Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

1992 • 2,096 citations

Telomere reduction in human colorectal carcinoma and with ageing

1990 • 1,672 citations

Telomerase activity in human germline and embryonic tissues and cells

1996 • 1,345 citations

Telomere elongation in immortal human cells without detectable telomerase activity.

1995 • 1,249 citations

Structure and variability of human chromosome ends.

1990 • 833 citations

Telomerase activity in normal and malignant hematopoietic cells.

1995 • 748 citations

TLC1 : Template RNA Component of Saccharomyces cerevisiae Telomerase

1994 • 727 citations

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1990 • 632 citations

Telomerase activity in normal leukocytes and in hematologic malignancies

1995 • 619 citations

Telomere Shortening Is Associated with Cell Division in Vitro and in Vivo

1995 • 528 citations

Telomerase, Cell Immortality, and Cancer

1994 • 405 citations

Telomerase activity in human cancer

1996 • 399 citations

Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes

1994 • 360 citations

Runaway telomere elongation caused by telomerase RNA gene mutations

1995 • 338 citations

Telomeres and telomerase in aging and cancer

1995 • 328 citations

Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis

1996 • 291 citations

Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids.

1996 • 156 citations

Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?

1995 • 121 citations

Aging and cancer: are telomeres and telomerase the connection?

1995 • 109 citations

TELOMERES AND TELOMERASE IN HUMAN CANCER (REVIEW)

1995 • 106 citations

9 Telomeres and Aging

1995 • 72 citations