Expressed var Genes Are Found in Plasmodium falciparum Subtelomeric Regions

Human Malaria Parasites in Continuous Culture

1976 • 7,687 citations

Cloning of Large Segments of Exogenous DNA into Yeast by Means of Artificial Chromosome Vectors

1987 • 1,517 citations

The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes

1995 • 1,223 citations

Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes

1995 • 1,035 citations

Switches in expression of plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes

1995 • 1,003 citations

Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration.

1985 • 839 citations

Genetic Analysis of the Human Malaria Parasite Plasmodium falciparum

1987 • 719 citations

Rapid switching to multiple antigenic and adhesive phenotypes in malaria

1992 • 636 citations

Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

1990 • 541 citations

Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes.

1984 • 451 citations

Programmed Gene Rearrangements Altering Gene Expression

1987 • 312 citations

Control of gene expression in trypanosomes

1995 • 291 citations

Surface alterations of erythrocytes in Plasmodium falciparum malaria. Antigenic variation, antigenic diversity, and the role of the spleen.

1983 • 231 citations

Homologous recombination within subtelomeric repeat sequences generates chromosome size polymorphisms in P. falciparum

1988 • 230 citations

A histidine-rich protein gene marks a linkage group favored strongly in a genetic cross of Plasmodium falciparum

1987 • 211 citations

Size variation in chromosomes from independent cultured isolates of Plasmodium falciparum

1985 • 201 citations

Chromosome size polymorphisms in plasmodium falciparum can involve deletions and are frequent in natural parasite populations

1986 • 178 citations

Cytoadherence by Plasmodium falciparum-infected erythrocytes is correlated with the expression of a family of variable proteins on infected erythrocytes.

1988 • 171 citations

A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei

1995 • 145 citations

A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei

1995 • 139 citations

Adherence of infected erythrocytes to venular endothelium selects for antigenic variants of Plasmodium falciparum.

1992 • 133 citations

Reduced extension temperatures required for PCR amplification of extremely A+T-rich DNA

1996 • 126 citations

AntigenicVariation in African Trypanosomes

1994 • 124 citations

Isolation of multiple sequences from the Plasmodium falciparum genome that encode conserved domains homologous to those in erythrocyte-binding proteins.

1995 • 121 citations

The Pf332 gene of Plasmodium falciparum codes for a giant protein that is translocated from the parasite to the membrane of infected erythrocytes

1992 • 106 citations

Gene inactivation of Pf11-1 of Plasmodium falciparum by chromosome breakage and healing: identification of a gametocyte-specific protein with a potential role in gametogenesis.

1992 • 100 citations

Mechanisms of Antigenic Variation in Borrelia hermsii and African Trypanosomes

1995 • 94 citations

Parasitism and chromosome dynamics in protozoan parasites: is there a connection?

1995 • 77 citations

The polymorphic subtelomeric regions of Plasmodium falciparum chromosomes contain arrays of repetitive sequence elements.

1994 • 73 citations

Long-range restriction maps of Plasmodium falciparum chromosomes: Crossingover and size variation among geographically distant isolates

1988 • 72 citations

Highly reiterated non-coding sequence in the genome of Plasmodium falciparum is composed of 21 base-pair tandem repeats

1985 • 67 citations

Protective antibodies against erythrocytic stages of Plasmodium falciparum in experimental infection of the squirrel monkey, Saimiri sciureus

1982 • 63 citations

Transcriptional differences in polymorphic and conserved domains of a complete cloned P. falciparum chromosome

1993 • 61 citations

Interchromosomal exchange of a large subtelomeric segment in a Plasmodium falciparum cross.

1994 • 59 citations

Towards a high-resolution map of the Plasmodium falciparum genome

1992 • 58 citations

Chromosome 9 from independent clones and isolates of Plasmodium falciparum undergoes subtelomeric deletions with similar breakpoints in vitro

1990 • 54 citations

Characterization of yeast artificial chromosomes from Plasmodium falciparum: Construction of a stable, representative library and cloning of telomeric DNA fragments

1992 • 43 citations

Compartmentalization of genes coding for immunodominant antigens to fragile chromosome ends leads to dispersed subtelomeric gene families and rapid gene evolution in Plasmodium falciparum

1996 • 41 citations

Restriction polymorphisms and fingerprint patterns from an interspersed repetitive element of Plasmodium falciparum DNA

1993 • 34 citations

Use of vectorette and subvectorette PCR to isolate transgene flanking DNA.

1994 • 25 citations

A YAC contig map of Plasmodium falciparum chromosome 4: characterization of a DNA amplification between two recently separated isolates

1995 • 23 citations

Chromosome Mapping Methods for Parasitic Protozoa

2003 • 17 citations

Plasmodium telomeres and telomere proximal gene expression

1996 • 16 citations

The Squirrel Monkey as an Experimental Model for Plasmodium falciparum Erythrocyte Rosette Formation

1992 • 14 citations

A 40-kilobase subtelomeric region is common to most Plasmodium falciparum 3D7 chromosomes

1993 • 12 citations

Karyotype analysis of virulent Plasmodium falciparum strains propagated in Saimiri sciureus: strain adaptation leads to deletion of the RESA gene

1995 • 6 citations