Vaccination with Phosphoglycan-Deficient Leishmania major Protects Highly Susceptible Mice from Virulent Challenge without Inducing a Strong Th1 Response

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

2002 • 1,733 citations

The immunology of susceptibility and resistance to Leishmania major in mice

2002 • 1,173 citations

Similarities and differences in CD4+ and CD8+ effector and memory T cell generation

2003 • 865 citations

T Cell Memory

2002 • 529 citations

A limiting dilution assay for quantifying Leishmania major in tissues of infected mice

1985 • 508 citations

Establishment of Stable, Cell-Mediated Immunity that Makes "Susceptible" Mice Resistant to Leishmania major

1992 • 503 citations

Double targeted gene replacement for creating null mutants.

1991 • 323 citations

Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasiteLeishmania major

2000 • 298 citations

Gene replacement in parasitic protozoa

1990 • 238 citations

Leishmania mexicanaCysteine Proteinase-Deficient Mutants Have Attenuated Virulence for Mice and Potentiate a Th1 Response

1998 • 235 citations

Development of a safe live Leishmania vaccine line by gene replacement.

1995 • 224 citations

IL-12 Is Required to Maintain a Th1 Response DuringLeishmania majorInfection

2000 • 207 citations

Human leishmaniases: epidemiology and public health aspects.

1992 • 198 citations

Immune Elimination ofLeishmania majorin Mice: Implications for Immune Memory, Vaccination, and Reactivation Disease

2001 • 176 citations

Persistence Without Pathology in Phosphoglycan-Deficient Leishmania major

2003 • 170 citations

A Specialized Pathway Affecting Virulence Glycoconjugates of Leishmania

1995 • 156 citations

Golgi GDP-mannose Uptake Requires Leishmania LPG2

1997 • 149 citations

Vaccines against leishmaniasis

1995 • 147 citations

Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania.

1993 • 125 citations

Regulation of macrophage IL-12 synthesis byLeishmania phosphoglycans

1999 • 92 citations

Phosphoglycan Repeat-deficient Leishmania mexicana Parasites Remain Infectious to Macrophages and Mice

2001 • 86 citations

Vervet Monkeys Vaccinated with KilledLeishmania majorParasites and Interleukin-12 Develop a Type 1 Immune Response but Are Not Protected against Challenge Infection

2001 • 79 citations

VACCINATION AGAINST CUTANEOUS LEISHMANIASIS IN MICE USING NONPATHOGENIC CLONED PROMASTIGOTES OF LEISHMANIA MAJOR AND IMPORTANCE OF ROUTE OF INJECTION

1984 • 70 citations

Study of the safety, immunogenicity and efficacy of attenuated and killed Leishmania (Leishmania) major vaccines in a rhesus monkey (Macaca mulatta) model of the human disease

2002 • 66 citations

Characterization of the immunological memory state generated in mice susceptible to Leishmania major following exposure to low doses of L. major and resulting in resistance to a normally pathogenic challenge

1996 • 65 citations

Defective galactofuranose addition in lipophosphoglycan biosynthesis in a mutant of Leishmania donovani.

1993 • 57 citations

A dhfr-ts- Leishmania major Knockout Mutant Cross-protects against Leishmania amazonensis

1999 • 55 citations

Immunogenicity and safety of autoclaved Leishmania major plus BCG vaccine in healthy Sudanese volunteers

2001 • 50 citations

LEISHMANIA TROPICA MAJOR IN MICE: VACCINATION AGAINST CUTANEOUS LEISHMANIASIS IN MICE OF HIGH GENETIC SUSCEPTIBILITY

1983 • 46 citations

Development of vaccines against leishmaniasis.

1990 • 45 citations