Quantification of the relative contribution of major histocompatibility complex (MHC) and non-MHC genes to human immune responses to foreign antigens

Human Genetics. Problems and Approaches.

1980 • 1,010 citations

Characterization of a panel of highly variable minisatellites cloned from human DNA

1987 • 534 citations

A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

1988 • 384 citations

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

1987 • 367 citations

Mannose binding protein gene mutations associated with unusual and severe infections in adults

1995 • 357 citations

Helicobacter pylori Infection: Genetic and Environmental Influences: A Study of Twins

1994 • 283 citations

Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.

1988 • 264 citations

Analysis of family resemblance. II. A linear model for familial correlation.

1974 • 229 citations

Fca Receptor Iia (Cd32) Polymorphism In Fulminant Meningococcal Septic

1994 • 200 citations

Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum

1988 • 180 citations

Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparum.

1991 • 152 citations

Genetic control of host resistance to infection

1994 • 133 citations

Processing of the precursor to the major merozoite surface antigens ofPlasmodium falciparum

1987 • 130 citations

Recombination rates across the HLA complex: use of microsatellites as a rapid screen for recombinant chromosomes

1995 • 113 citations

HLA Disease Associations: Models for the Study of Complex Human Genetic Disorders

1995 • 86 citations

Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children

1990 • 75 citations

TWINAN90: A FORTRAN program for conducting ANOVA-based and likelihood-based analyses of twin data

1992 • 74 citations

T and B cell responses of Plasmodium falciparum malaria-immune individuals to synthetic peptides corresponding to sequences in different regions of the P. falciparum antigen Pf155/RESA.

1989 • 69 citations

Association between immune recognition of the malaria vaccine candidate antigen Pf155/RESA and resistance to clinical disease: a prospective study in a malaria-endemic region of West Africa

1991 • 68 citations

Genetic regulation of human anti-malarial antibodies in twins.

1992 • 68 citations

Structural requirements for the interaction between peptide antigens and I-Ed molecules.

1989 • 65 citations

Identical peptides recognized by MHC class I- and II-restricted T cells.

1989 • 63 citations

Immune response to soluble exoantigens of Plasmodium falciparum may contribute to both pathogenesis and protection in clinical malaria: evidence from a longitudinal, prospective study of semi‐immune African children

1991 • 62 citations

The statistical analysis of data from immunoepidemiological studies

1992 • 57 citations

Mapping of genes controlling quantitative antibody production in Biozzi mice.

1995 • 53 citations

MHC and malaria: the relationship between HLA class II alleles and immune responses to Plasmodium falciprum

1992 • 50 citations

Cellular and humoral immune responses to Plasmodium falciparum gametocyte antigens in malaria-immune individuals. Limited response to the 48/45-kilodalton surface antigen does not appear to be due to MHC restriction.

1990 • 49 citations

GENETIC FACTORS CONTROLLING ANTI-SHEEP ERYTHROCYTE ANTIBODY RESPONSE AND IMMUNOGLOBULIN SYNTHESIS IN BACKCROSS AND F2 PROGENY OF MICE GENETICALLY SELECTED FOR "HIGH" OR "LOW" ANTIBODY SYNTHESIS

1972 • 45 citations

The influence of genetic factors on the immune response as judged by pneumococcal vaccination of mono- and dizygotic Caucasian twins

1993 • 42 citations

Structural and Antigenic Polymorphism of the 35- to 48-Kilodalton Merozoite Surface Antigen (MSA-2) of the Malaria Parasite Plasmodium falciparum

1991 • 41 citations

T cell receptor V beta gene expression in monozygotic twins. Discordance in CD8 subset and in disease states.

1994 • 41 citations

Failure to detect MHC class II associations of the human immune response induced by repeated malaria infections to the Plasmodium falciparum antigen Pf155/RESA

1991 • 37 citations

Morphology and movement of corneal surface cells in humans

1992 • 33 citations

HL‐A Linked Genetic Control of Immune Response in Man

1975 • 31 citations

Secretor status and heterosexual transmission of HIV.

1991 • 30 citations

Segregation analysis indicates a major gene in the control of interleukine-5 production in humans infected with Schistosoma mansoni.

1996 • 28 citations

Recombinant Plasmodium Falciparum Glutamate Rich Protein; Purification and use in Enzyme-Linked Immunosorbent Assay

1991 • 28 citations

HLA polymorphism and T cell recognition of a conserved region of p190, a malaria vaccine candidate

1991 • 27 citations

Measuring cellular immune responses to malaria antigens in endemic populations: Epidemiological, parasitological and physiological factors which influence in vitro assays

1990 • 22 citations

Comparative study of the T cell response to two allelic forms of a malarial vaccine candidate protein.

1992 • 18 citations

Amino acid sequences recognized by T cells: studies on a merozoite surface antigen from the FCQ-27/PNG isolate of Plasmodium falciparum

1990 • 15 citations

Characterization of Naturally Acquired Antibodies to the non-Repetitive Flanking Regions of the Circumsporozoite Protein of Plasmodium Falciparum

1992 • 11 citations

Presentation of the Plasmodium falciparum antigen Pf155/RESA to human T cells. Variations in responsiveness induced by antigen presenting cells from different but MHC class II identical donors

1994 • 5 citations

Infection … by the new genetics

1996 • 4 citations

Molecular aspects of autoimmunity: a review

1992 • 2 citations