Association between immune recognition of the malaria vaccine candidate antigen Pf155/RESA and resistance to clinical disease: a prospective study in a malaria-endemic region of West Africa

Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa

1987 • 636 citations

Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection

1989 • 451 citations

Antibodies in malarial sera to parasite antigens in the membrane of erythrocytes infected with early asexual stages of Plasmodium falciparum.

1984 • 264 citations

Multiple cross‐reactivities amongst antigens of Plasmodium falciparum impair the development of protective immunity against malaria

1986 • 235 citations

Immune sera recognize on erythrocytes a Plasmodium falciparum antigen composed of repeated amino acid sequences

1984 • 226 citations

Structure of the RESA gene ofPiasmodium falciparum

1986 • 185 citations

Human antibodies to a Mr 155,000 Plasmodium falciparum antigen efficiently inhibit merozoite invasion.

1984 • 157 citations

Rabbit and human antibodies to a repeated amino acid sequence of a Plasmodium falciparum antigen, Pf 155, react with the native protein and inhibit merozoite invasion.

1986 • 111 citations

Pf155/RESA antigen is localized in dense granules of Plasmodium falciparum merozoites

1990 • 105 citations

Dissection of the human antibody response to the malaria antigen Pf155/RESA into epitope specific components

1989 • 101 citations

The ring-infected erythrocyte surface antigen (RESA) polypeptide of Plasmodium falciparum contains two separate blocks of tandem repeats encoding antigenic epitopes that are naturally immunogenic in man.

1984 • 86 citations

Cross–reactive antigenic determinants present on different Plasmodium falciparum blood–stage antigens

1989 • 84 citations

Monoclonal antibody two-site ELISA for human IFN-γ

1989 • 79 citations

Anti-Plasmodium falciparum Antibodies Acquired by Residents in a Holoendemic Area of Liberia During Development of Clinical Immunity

1986 • 75 citations

Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children

1990 • 75 citations

T and B cell responses of Plasmodium falciparum malaria-immune individuals to synthetic peptides corresponding to sequences in different regions of the P. falciparum antigen Pf155/RESA.

1989 • 69 citations

T-cell epitopes in Pf155/RESA, a major candidate for a Plasmodium falciparum malaria vaccine.

1988 • 51 citations

Natural Antibodies against Three Distinct and Defined Antigens of Plasmodium falciparum in Residents of a Mesoendemic Area in Gabon

1988 • 45 citations

Absence of antigenic diversity in Pf155, a major parasite antigen in membranes of erythrocytes infected with Plasmodium falciparum

1987 • 45 citations

A longitudinal study of antibodies to the Plasmodium falciparum antigen Pf155/RESA and immunity to malaria infection in adult Liberians

1990 • 44 citations

ChemInform Abstract: Simultaneous Multiple Peptide Synthesis: The Rapid Preparation of Large Numbers of Discrete Peptides for Biological, Immunological, and Methodological Studies

1987 • 44 citations

Identification of T epitopes within a potential Plasmodium falciparum vaccine antigen. A study of human lymphocyte responses to repeat and nonrepeat regions of Pf155/RESA.

1988 • 42 citations

Class II restriction in mice to the malaria candidate vaccine ring infected erythrocyte surface antigen (RESA) as synthetic peptides or as expressed in recombinant vaccinia.

1989 • 37 citations

Regulation of the immune response in Plasmodium falciparum malaria: IV. T cell dependent production of immunoglobulin and anti-P. falciparum antibodies in vitro.

1987 • 33 citations

Consecutive determinations of seroreactivities to Pf 155/RESA antigen and to its different repetitive sequences in adult men from a holoendemic area of Liberia

1990 • 26 citations

Simultaneous multiple peptide synthesis: The rapid preparation of large numbers of discrete peptides for biological, immunological, and methodological studies

1988 • 25 citations

Age-related prevalence of antibody response against three different, defined Plasmodium falciparum antigens in children from the Haut-Ogooué province in Gabon

1989 • 22 citations

Antibodies to the PF155 Antigen of Plasmodium falciparum: Measurement by Cell-ELISA and Correlation with Expected Immune Protection

1987 • 20 citations