Contrasts in codon usage of latent versus productive genes of Epstein-Barr virus: data and hypotheses

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

DNA sequence and expression of the B95-8 Epstein—Barr virus genome

1984 • 2,039 citations

Codon usage and tRNA content in unicellular and multicellular organisms.

1985 • 1,724 citations

The Complete DNA Sequence of the Long Unique Region in the Genome of Herpes Simplex Virus Type 1

1988 • 1,618 citations

Codon selection in yeast.

1982 • 1,580 citations

The Complete DNA Sequence of Varicella-Zoster Virus

1986 • 1,425 citations

Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: A proposal for a synonymous codon choice that is optimal for the E. coli translational system

1981 • 1,405 citations

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.

1987 • 1,087 citations

Codon catalog usage is a genome strategy modulated for gene expressivity

1981 • 951 citations

The Mosaic Genome of Warm-Blooded Vertebrates

1985 • 887 citations

An evolutionary perspective on synonymous codon usage in unicellular organisms

1986 • 874 citations

Directional mutation pressure and neutral molecular evolution.

1988 • 872 citations

Preferential codon usage in prokaryotic genes: the optimal codon-anticodon interaction energy and the selective codon usage in efficiently expressed genes

1982 • 850 citations

Codon catalog usage and the genome hypothesis

1980 • 772 citations

Codon usage tabulated from the GenBank Genetic Sequence Data

1988 • 608 citations

Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1

1985 • 523 citations

Analysis of Mutation in Human Cells by Using an Epstein-Barr Virus Shuttle System

1987 • 513 citations

Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

1985 • 502 citations

Compositional constraints and genome evolution

1986 • 451 citations

A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting components.

1985 • 442 citations

Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.

1987 • 397 citations

Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus

1988 • 386 citations

Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoter.

1986 • 359 citations

Helix-random coil transitions in DNA homopolymer pairs

1964 • 289 citations

Synonymous codon usage inBacillus subtilisreflects both translational selection and mutational biases

1987 • 281 citations

Nonrandom utilization of codon pairs in Escherichia coli.

1989 • 264 citations

A promoter of Epstein-Barr virus that can function during latent infection can be transactivated by EBNA-1, a viral protein required for viral DNA replication during latent infection

1989 • 254 citations

Viral latency and transformation: The strategy of Epstein-Barr virus

1989 • 241 citations

Nucleotide sequences of mRNAs encoding Epstein-Barr virus nuclear proteins: a probable transcriptional initiation site.

1986 • 230 citations

Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4

1988 • 225 citations

One of two Epstein-Barr virus nuclear antigens contains a glycine-alanine copolymer domain.

1983 • 212 citations

A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome.

1988 • 199 citations

A Putative Origin of Replication of Plasmids Derived from Epstein-Barr Virus Is Composed of Two cis-Acting Components

1985 • 182 citations

Evolution of chromosome bands: Molecular ecology of noncoding DNA

1989 • 178 citations

Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouse.

1989 • 167 citations

Two related Epstein-Barr virus membrane proteins are encoded by separate genes

1989 • 161 citations

Compositional patterns in vertebrate genomes: Conservation and change in evolution

1988 • 142 citations

Local stability of DNA and RNA secondary structure and its relation to biological functions

1986 • 141 citations

Silent nucleotide substitutions and G+C content of some mitochondrial and bacterial genes

1986 • 131 citations

A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus

1987 • 122 citations

Genetic Relations between Varicella-Zoster Virus and Epstein-Barr Virus

1987 • 113 citations

Sense codons are found in specific contexts

1985 • 111 citations

An Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA5) partly encoded by the transformation-associated Bam WYH region of EBV DNA: preferential expression in lymphoblastoid cell lines.

1986 • 110 citations

Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: a potentially polycistronic message generated by long-range splicing of several exons.

1985 • 104 citations

Correlation between molecular clock ticking, codon usage, fidelity of DNA repair, chromosome banding and chromatin compactness in germline cells

1987 • 102 citations

Epstein-Barr virus mRNAs produced by alternative splicing

1986 • 100 citations

Constraints on codon context in Escherichia coli genes their possible role in modulating the efficiency of translation

1986 • 98 citations

A fifth Epstein-Barr virus nuclear protein (EBNA3C) is expressed in latently infected growth-transformed lymphocytes

1988 • 87 citations

An Epstein-Barr virus transcription unit is at least 84 kilobases long

1986 • 84 citations

Spliced RNA from the IR1-U2 region of Epstein-Barr virus: presence of an open reading frame for a repetitive polypeptide.

1984 • 82 citations

An intricate route to immortality

1989 • 70 citations

Purification of the Epstein-Barr virus-determined nuclear antigen from Epstein-Barr virus-transformed human lymphoid cell lines

1978 • 65 citations

Contextual constraints on synonymous codon choice

1983 • 65 citations

BamHI E region of the Epstein-Barr virus genome encodes three transformation-associated nuclear proteins.

1988 • 62 citations

Preferential codon usage in genes

1981 • 62 citations

Identification and characterization of a cellular protein that cross-reacts with the Epstein-Barr virus nuclear antigen

1984 • 51 citations

Repeat arrays in cellular DNA related to the Epstein-Barr virus IR3 repeat.

1985 • 45 citations

A method to identify distinctive charge configurations in protein sequences, with application to human herpesvirus polypeptides

1989 • 43 citations

Comparative statistics for DNA and protein sequences: multiple sequence analysis.

1985 • 40 citations

Approaches to Physical Mapping of the Human Genome

1986 • 31 citations

Choice of base at silent codon site 3 is not selectively neutral in eucaryotic structural genes: It maintains excess short runs of weak and strong hydrogen bonding bases

1983 • 26 citations

Two Distinct Compositional Classes of Vertebrate Gene-Bearing DNA Stretches, Their Structures and Possible Evolutionary Origin

1987 • 23 citations

Nucleotide sequence of a plasmid born streptothricin-acetyl-transferase gene (sat-1)

1989 • 22 citations

Analysis of the Codon Bias inE. coliSequences

1984 • 20 citations

Codon usage in the vertebrate hemoglobins and its implications.

1985 • 18 citations

Repeat Arrays in Cellular DNA Related to the Epstein-Barr Virus IR3 Repeat

1985 • 16 citations

Distinctive charge configurations in proteins of the Epstein-Barr virus and possible functions.

1988 • 11 citations

A fused chimeric protein made in human cells

1989 • 10 citations

Trans-Splicing of RNA

1989 • 10 citations

A model for the development of the tandem repeat units in the EBV ori-P region and a discussion of their possible function

1987 • 9 citations

Similarities between the DNA molecules of bacteriophages 424, λ, and 21, determined by denaturation and electron microscopy

1975 • 6 citations