Adenosine stimulates DNA fragmentation in human thymocytes by Ca2+-mediated mechanisms

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

1981 • 1,655 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS

1979 • 1,370 citations

Subclasses of external adenosine receptors.

1980 • 1,087 citations

The role of adenosine in the regulation of coronary blood flow.

1980 • 877 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1977 • 726 citations

Two distinct adenosine-sensitive sites on adenylate cyclase.

1977 • 574 citations

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

1993 • 554 citations

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.

1989 • 537 citations

2,3,7,8-Tetrachlorodibenzo- p -Dioxin Kills Immature Thymocytes by Ca ²⁺ -Mediated Endonuclease Activation

1988 • 460 citations

Apoptosis: molecular mechanisms in programmed cell death.

1991 • 425 citations

The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

1992 • 387 citations

Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complex.

1989 • 315 citations

Adenosine receptors and calcium: Basis for proposing a third (A3) adenosine receptor

1986 • 284 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Effect of Forskolin on Voltage-Gated K ⁺ Channels Is Independent of Adenylate Cyclase Activation

1988 • 269 citations

2,5-Di-(tert-butyl)-1,4-benzohydroquinone rapidly elevates cytosolic Ca2+ concentration by mobilizing the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool

1989 • 261 citations

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

1991 • 249 citations

Regulation of adenylate cyclase by adenosine

1979 • 218 citations

Lymphocyte Hormone Receptors

1987 • 216 citations

Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.

1986 • 198 citations

Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen-stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor.

1990 • 190 citations

Tributyltin stimulates apoptosis in rat thymocytes

1990 • 187 citations

Hormone secretagogues increase cytosolic calcium by increasing cAMP in corticotropin-secreting cells.

1985 • 169 citations

Modulation of Acetylcholine Receptor Desensitization by Forskolin Is Independent of cAMP

1988 • 154 citations

Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage.

1990 • 137 citations

P1- and P2-purinoceptor subtypes--an update.

1990 • 126 citations

A role for a pre-T-cell receptor in T-cell development

1993 • 114 citations

Ca²⁺ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca²⁺ stores. A study with the Ca²⁺ endoplasmic reticulum‐ATPase inhibitor thapsigargin

1990 • 106 citations

Biochemical events in naturally occurring forms of cell death

1993 • 104 citations

Adenosine Receptors

1990 • 104 citations

Cardiac effects of adenosine and adenosine analogs in guinea-pig atrial and ventricular preparations: evidence against a role of cyclic AMP and cyclic GMP.

1985 • 101 citations

Extracellular ATP causes lysis of mouse thymocytes and activates a plasma membrane ion channel

1991 • 100 citations

Regulation of GH3-cell function via adenosine A1 receptors. Inhibition of prolactin release, cyclic AMP production and inositol phosphate generation

1988 • 87 citations

CD4⁺CD8⁺ thymocytes are susceptible to DNA fragmentation induced by phorbol ester, calcium ionophore and anti‐CD3 antibody

1990 • 78 citations

Beta-adrenergic receptor stimulation induces inositol trisphosphate production and Ca2+ mobilization in rat parotid acinar cells.

1988 • 76 citations

Cyclic AMP potentiates glucocorticoid‐induced endogenous endonuclease activation in thymocytes ¹

1993 • 59 citations

Further Studies on the Role of Calcium in Glucocorticoid-Induced Lymphocytolysis*

1978 • 57 citations

Ca-antagonistic effects of adenosine in guinea pig atrial cells

1988 • 56 citations

Adenosine receptor-mediated calcium mobilization in cortical collecting tubule cells

1988 • 52 citations

Evidence for cAMP-dependent Protein Kinase in Mediating the Parathyroid Hormone-stimulated Rise in Cytosolic Free Calcium in Rabbit Connecting Tubules

1989 • 43 citations

Inhibition of radioligand binding to A1 adenosine receptors by bay k8644 and nifedipine

1987 • 33 citations

The effect of various concentrations of nucleobases, nucleosides or glutamine on the incorporation of [3H]thymidine into DNA in rat mesenteric-lymph-node lymphocytes stimulated by phytohaemagglutinin

1990 • 30 citations

The effect of time of addition of glutamine or nucleosides on proliferation of rat cervical lymph-node T-lymphocytes after stimulation by concanavalin A

1991 • 20 citations

Alteration of mast cell responsiveness to adenosine by pertussis toxin

1988 • 15 citations

Cobalt ion enhancement of 2-chloro[3H]adenosine binding to a novel class of adenosine receptors in brain: antagonism by calcium

1985 • 8 citations

The rate of the AMP/adenosine substrate cycle in concanavalin-A-stimulated rat lymphocytes

1989 • 5 citations