Effect of R-verapamil on the pharmacokinetics of paclitaxel in women with breast cancer.

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1991 • 962 citations

Multiple-Drug Resistance in Human Cancer

1987 • 703 citations

Clinical toxicities encountered with paclitaxel (Taxol).

1993 • 682 citations

Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans.

1995 • 550 citations

Phase I clinical and pharmacokinetic study of taxol.

1987 • 449 citations

Mlab — A mathematical modeling tool

1979 • 391 citations

Single cell analysis of daunomycin uptake and efflux in multidrug-resistant and -sensitive KB cells: effects of verapamil and other drugs.

1986 • 312 citations

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients.

1993 • 311 citations

Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance.

1992 • 298 citations

Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.

1987 • 286 citations

Potentiation of vincristine and Adriamycin effects in human hemopoietic tumor cell lines by calcium antagonists and calmodulin inhibitors.

1983 • 250 citations

Identification of P450 enzymes involved in metabolism of verapamil in humans

1993 • 200 citations

A phase I trial of taxol given by a 6-hour intravenous infusion.

1991 • 185 citations

The effect of verapamil on the pharmacokinetics of adriamycin

1986 • 146 citations

Saturable pharmacokinetics and paclitaxel pharmacodynamics in children with solid tumors.

1994 • 138 citations

High-performance liquid chromatographic assay for taxol in human plasma and urine and pharmacokinetics in a phase I trial.

1987 • 112 citations

Phase I study of taxol administered as a short i.v. infusion daily for 5 days.

1987 • 103 citations

The clinical pharmacology of paclitaxel (Taxol).

1993 • 93 citations

Modulation by verapamil of vincristine pharmacokinetics and toxicity in mice bearing human tumor xenografts

1989 • 78 citations

Phase I crossover study of paclitaxel with r-verapamil in patients with metastatic breast cancer.

1996 • 73 citations

Steady-state plasma concentrations and effects of taxol for a 250 mg/m2 dose in combination with granulocyte-colony stimulating factor in patients with ovarian cancer

1993 • 62 citations

Effects of verapamil on the pharmacokinetics of daunomycin in the rat

1987 • 36 citations

Increased quinidine plasma concentrations during administration of verapamil: A new quinidine-verapamil interaction

1986 • 32 citations