Saturable pharmacokinetics and paclitaxel pharmacodynamics in children with solid tumors.

Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations

1978 • 2,054 citations

Some suggestions for measuring predictive performance

1981 • 1,576 citations

Taxol: A Unique Antineoplastic Agent with Significant Activity in Advanced Ovarian Epithelial Neoplasms

1989 • 1,111 citations

THE IMPACT OF NATIONAL CANCER ACT

1991 • 809 citations

Clinical toxicities encountered with paclitaxel (Taxol).

1993 • 682 citations

Phase I clinical and pharmacokinetic study of taxol.

1987 • 449 citations

Sequences of taxol and cisplatin: a phase I and pharmacologic study.

1991 • 438 citations

Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.

1987 • 286 citations

Phase II study and long-term follow-up of patients treated with taxol for advanced ovarian adenocarcinoma.

1992 • 264 citations

Phase I and pharmacodynamic study of taxol in refractory acute leukemias.

1989 • 196 citations

A phase I trial of taxol given by a 6-hour intravenous infusion.

1991 • 185 citations

A phase II study of taxol in patients with malignant melanoma

1991 • 179 citations

A phase II trial of taxol in metastatic melanoma

1990 • 175 citations

High-performance liquid chromatographic assay for taxol in human plasma and urine and pharmacokinetics in a phase I trial.

1987 • 112 citations

Phase I trial of paclitaxel in children with refractory solid tumors: a Pediatric Oncology Group Study.

1993 • 85 citations

Analysis of anticancer drugs in biological fluids: determination of taxol with application to clinical pharmacokinetics

1990 • 64 citations

Tolerance to antineoplastic agents in children and adults.

1985 • 63 citations

Effect of plasma protein and tissue binding on the time course of drug concentration in plasma

1979 • 63 citations

Clinical pharmacokinetics and pharmacodynamics of anticancer drugs in children.

1993 • 42 citations

Concept of maximum tolerated systemic exposure and its application to phase I‐II studies of anticancer drugs

1991 • 33 citations

Evaluation of toxicity: clinical issues.

1980 • 22 citations

Accumulation kinetics of drugs with nonlinear plasma protein and tissue binding characteristics

1979 • 17 citations

Pharmacokinetics of Capacity-Limited Tissue Distribution of Methicillin in Rabbits

1984 • 14 citations