Expression of a type II collagen gene in the zebrafish embryonic axis

Stages of embryonic development of the zebrafish

1995 • 11,263 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

1993 • 1,086 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

[12] Unidirectional digestion with exonuclease III in DNA sequence analysis

1987 • 898 citations

Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos

1993 • 892 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

1994 • 786 citations

Cloning of the zebrafishkrox-20gene (krx-20) and its expression during hindbrain development

1993 • 708 citations

Control of cell pattern in the developing nervous system: Polarizing activity of the floor plate and notochord

1991 • 698 citations

Origin and organization of the zebrafish fate map

1990 • 692 citations

The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo

1992 • 648 citations

no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene

1994 • 628 citations

Autoproteolysis in hedgehog protein biogenesis

1994 • 541 citations

THE FAMILY OF COLLAGEN GENES

1990 • 511 citations

Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation

1993 • 502 citations

Segment and cell type lineage restrictions during pharyngeal arch development in the zebrafish embryo

1994 • 487 citations

Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate

1993 • 470 citations

Embryonic Development and Induction

1938 • 459 citations

Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish

1993 • 458 citations

Two-color whole-mount in situ hybridization to vertebrate and Drosophila embryos

1994 • 438 citations

The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system

1991 • 432 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 406 citations

A Genetic Linkage Map for the Zebrafish

1994 • 385 citations

Whole-mount in situ hybridizationon zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes

1994 • 382 citations

The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos.

1992 • 371 citations

A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest

1989 • 339 citations

Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis

1992 • 332 citations

The Biology of Osteoarthritis

1989 • 326 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 308 citations

Development of the short‐tailed mutant in the house mouse

1935 • 305 citations

Nucleotide sequences of complementary deoxyribonucleic acids for the pro.alpha.1 chain of human type I procollagen. Statistical evaluation of structures that are conserved during evolution

1983 • 304 citations

Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos

1994 • 294 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Vertebrate Embryonic Induction: Mesodermal and Neural Patterning

1994 • 286 citations

Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos.

1993 • 283 citations

Induction of floor plate differentiation by contact-dependent, homeogenetic signals

1993 • 271 citations

Expression of the mouse α1 (II) collagen gene is not restricted to cartilage during development

1991 • 264 citations

The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes

1991 • 259 citations

The winged-helix DNA-binding motif: Another helix-turn-helix takeoff

1993 • 242 citations

A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain.

1992 • 236 citations

Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene.

1993 • 234 citations

goosecoid Expression in neurectoderm and mesendoderm is disrupted in zebrafish cyclops gastrulas

1994 • 227 citations

Diversity of expression of engrailed-like antigens in zebrafish

1991 • 211 citations

Role of the floor plate in axonal patterning in the zebrafish CNS

1992 • 169 citations

Perturbation of neuronal differentiation and axon guidance in the spinal cord of mouse embryos lacking a floor plate: analysis of Danforth’s shorttail mutation

1991 • 168 citations

The expression of a zebrafish gene homologous to Drosophila snail suggests a conserved function in invertebrate and vertebrate gastrulation

1993 • 141 citations

Transient expression of collagen type II at epitheliomesenchymal interfaces during morphogenesis of the cartilaginous neurocranium

1986 • 131 citations

The transient expression of type II collagen at tissue interfaces during mammalian craniofacial development

1991 • 114 citations

Widespread distribution of type II collagen during embryonic chick development

1989 • 113 citations

Induction and axial patterning of the neural plate: Planar and vertical signals

1993 • 104 citations

Midline signaling in the primordium of the zebrafish anterior central nervous system.

1994 • 98 citations

The developmental specification of the vertebrate skull.

1988 • 97 citations

Expression of the zebrafish gene hlx-1 in the prechordal plate and during CNS development

1994 • 96 citations

An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.

1993 • 81 citations

Expression of two nonallelic type II procollagen genes during Xenopus laevis embryogenesis is characterized by stage-specific production of alternatively spliced transcripts.

1991 • 78 citations

Hedgehog, the floor plate, and the zone of polarizing activity

1994 • 71 citations

Genetic control of primary neuronal development in zebrafish

1991 • 60 citations

Midline cells and the organization of the vertebrate neuraxis

1993 • 43 citations

Alterations in gene expression during mesoderm formation and axial patterning in Brachyury (T) embryos.

1994 • 43 citations

XFKH2, a Xenopus HNF-3α Homologue, Exhibits Both Activin-Inducible and Autonomous Phases of Expression in Early Embryos

1993 • 40 citations

Nucleotide sequence of the full length cDNA encoding for human type II procollagen

1989 • 37 citations

Type II collagen distribution during cranial development in Xenopus laevis

1994 • 33 citations

Distribution of type II collagen mRNA in Xenopus embryos visualized by whole-mount in situ hybridization.

1992 • 26 citations

Temporal and spatial expression of genes for cartilage extracellular matrix proteins during avian mandibular arch development

1991 • 25 citations

Nucleotide and amino acid sequences of the entire human α1 (III) collagen

1989 • 22 citations

Midline structures and central nervous system coordinates in zebrafish.

1993 • 16 citations

Axis determination in Xenopus: Gradients and signals

1994 • 7 citations

SUSCEPTIBILITY TO RHEUMATOID ARTHRITIS IS NOT ASSOCIATED WITH A SINGLE COMMON ALLELE OF THE TYPE 2 COLLAGEN GENE (COL2A1)

1993 • 2 citations