NPK1, a tobacco gene that encodes a protein with a domain homologous to yeast BCK1, STE11, and Byr2 protein kinases.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

Raf-1 activates MAP kinase-kinase

1992 • 1,308 citations

[2] Protein kinase catalytic domain sequence database: Identification of conserved features of primary structure and classification of family members

1991 • 1,225 citations

The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product

1992 • 931 citations

Activation of the MAP kinase pathway by the protein kinase raf

1992 • 816 citations

Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase

1987 • 703 citations

Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro

1992 • 691 citations

Guide to Yeast Genetics and Molecular Biology

1991 • 607 citations

Overproduction of protein kinase C causesdisordered growth control in rat fibroblasts

1988 • 492 citations

A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle

1990 • 422 citations

A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C.

1993 • 373 citations

Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect.

1992 • 371 citations

Dominant Mutations in a Gene Encoding a Putative Protein Kinase (BCKT) Bypass the Requirement for a Saccharomyces cerevisiae Protein Kinase C Homolog

1992 • 322 citations

MKK1 and MKK2, Which Encode Saccharomyces cerevisiae Mitogen-Activated Protein Kinase-Kinase Homologs, Function in the Pathway Mediated by Protein Kinase C

1993 • 306 citations

Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.

1992 • 292 citations

Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein.

1992 • 292 citations

Microtubule-mediated control of microfibril deposition : a re-examination of the hypothesis

1991 • 263 citations

The Arabidopsis functional homolog of the p34cdc2 protein kinase.

1991 • 239 citations

Signal Transduction During Pheromone Response in Yeast

1991 • 225 citations

A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila

1993 • 217 citations

byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype.

1991 • 208 citations

Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells

1994 • 205 citations

Isolation and characterization of cDNA clones encoding a functional p34cdc2 homologue from Zea mays.

1991 • 201 citations

A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants

1991 • 197 citations

MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro

1993 • 190 citations

Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase.

1992 • 188 citations

Complementation of a yeast cell cycle mutant by an alfalfa cDNA encoding a protein kinase homologous to p34cdc2.

1991 • 187 citations

MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C.

1993 • 187 citations

cDNA cloning of MAP kinase kinase reveals kinase cascade pathways in yeasts to vertebrates.

1993 • 179 citations

STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast.

1990 • 178 citations

Orientation of Cortical Microtubules in Interphase Plant Cells

1991 • 178 citations

Genes regulating the plant cell cycle: isolation of a mitotic-like cyclin from Arabidopsis thaliana.

1992 • 171 citations

Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase.

1993 • 171 citations

Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms.

1993 • 166 citations

Isolation and characterization of cDNA clones for plant cyclins.

1991 • 159 citations

Ustilago maydis, the delightful blight

1992 • 155 citations

Cell division in higher plants: a cdc2 gene, its 34-kDa product, and histone H1 kinase activity in pea.

1990 • 152 citations

Identification of two cell-cycle-controlling cdc2 gene homologs in Arabidopsis thaliana

1991 • 150 citations

Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases.

1993 • 146 citations

Isolation of an auxin-regulated gene cDNA expressed during the transition from G0 to S phase in tobacco mesophyll protoplasts.

1989 • 139 citations

Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control.

1993 • 139 citations

MsERK1: a mitogen-activated protein kinase from a flowering plant.

1993 • 132 citations

Operation of an efficient site-specific recombination system ofZygosaccharomyces rouxiiin tobacco cells

1991 • 129 citations

Breakdown of Phosphatidylinositol during the Elicitation of Phytoalexin Production in Cultured Carrot Cells

1987 • 109 citations

A protein kinase C cDNA without the regulatory domain is active after transfection in vivo in the absence of phorbol ester.

1989 • 102 citations

Characterization of a staurosporine- and temperature-sensitive mutant, stt1, of Saccharomyces cerevisiae: STT1 is allelic to PKC1

1992 • 84 citations

Isolation and characterization of cDNA clones encodingcdc2 homologues fromOryza sativa: a functional homologue and cognate variants

1992 • 76 citations

Molecular cloning and characterization of the STE7 and STE11 genes of Saccharomyces cerevisiae.

1985 • 65 citations

Complementation of the cs dis2-11 cell cycle mutant of Schizosaccharomyces pombe by a protein phosphatase from Arabidopsis thaliana.

1992 • 53 citations

Ustilago maydis, the delightful blight

1992 • 42 citations

The Arabidopsis Functional Homolog of the p34 cdc2 Protein Kinase

1991 • 34 citations

Direct evidence that the kinase activity of protein kinase C is involved in transcriptional activation through a TPA‐responsive element

1989 • 30 citations

Phosphatidylserine activation of plant protein kinase C

1988 • 26 citations

Signal Transduction During Pheromone Response In Yeast

1991 • 21 citations

Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases.

1993 • 11 citations

A Protein Kinase C cDNA without the Regulatory Domain Is Active after Transfection In Vivo in the Absence of Phorbol Ester

1989 • 8 citations

MsERK1: A Mitogen-Activated Protein Kinase from a Flowering Plant

1993 • 6 citations