Cell-free synthesis and assembly of prolyl 4-hydroxylase: the role of the beta-subunit (PDI) in preventing misfolding and aggregation of the alpha-subunit.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum.

1982 • 1,765 citations

The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple-helix of collagen

1973 • 563 citations

Biochemistry of collagen

1977 • 429 citations

Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene.

1987 • 420 citations

Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum.

1992 • 405 citations

Radiolabeling of proteins by reductive alkylation with [14C]formaldehyde and sodium cyanoborohydride

1978 • 317 citations

A stereochemical concept for the catalytic mechanism of prolylhydroxylase

1982 • 265 citations

A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase.

1987 • 241 citations

Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro

1988 • 219 citations

Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein

1991 • 192 citations

Interaction of BiP with newly synthesized immunoglobulin light chain molecules: cycles of sequential binding and release.

1992 • 187 citations

Preparative in vitro mRNA synthesis using SP6 and T7 RNA polymerases

1991 • 155 citations

Site-directed mutagenesis of human protein disulphide isomerase: effect on the assembly, activity and endoplasmic reticulum retention of human prolyl 4-hydroxylase in Spodoptera frugiperda insect cells.

1992 • 152 citations

Structural properties of homogeneous protein disulphide-isomerase from bovine liver purified by a rapid high-yielding procedure

1983 • 148 citations

The reactivities and ionization properties of the active-site dithiol groups of mammalian protein disulphide-isomerase

1991 • 144 citations

Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts.

1989 • 134 citations

Conformational changes associated with proteolytic processing of presecretory proteins allow glutathione-catalyzed formation of native disulfide bonds.

1982 • 125 citations

BIP associates with newly synthesized subunits of the mouse muscle nicotinic receptor.

1991 • 108 citations

Cross-linking studies of the self-association properties of apo-A-I and apo-A-II from human high density lipoprotein.

1978 • 96 citations

Disulfide bond formation during the folding of influenza virus hemagglutinin.

1992 • 79 citations

Evaluation of the fidelity of initiation of translation in reticulocyte lysates from commercial sources

1990 • 71 citations

Human Prolyl Hydroxylase. Purification, Partial Characterization and Preparation of Antiserum to the Enzyme

1975 • 71 citations

Cell-free synthesis of enzymically active tissue-type plasminogen activator. Protein folding determines the extent of N-linked glycosylation

1992 • 57 citations

Prolyl 4-hydroxylase: molecular cloning and the primary structure of the alpha subunit from chicken embryo.

1989 • 57 citations

Design and synthesis of a consensus signal sequence that inhibits protein translocation into rough microsomal vesicles

1984 • 54 citations

Radioimmunoassay for Human and Chick Prolyl Hydroxylases

1975 • 53 citations

The assembly of tetrameric prolyl hydroxylase in tendon fibroblasts from newly synthesized α-subunits and from preformed cross-reacting protein

1980 • 51 citations

Beneficial effects of inhibitors of prolyl 4-hydroxylase in CCl4-induced fibrosis of the liver in rats

1991 • 46 citations

Characterization of the oligosaccharides of prolyl hydroxylase, a microsomal glycoprotein

1985 • 35 citations

Phase separation of rat intestinal brush border membrane proteins using Triton X-114

1986 • 33 citations

Cotranslational glycosylation of proteins in systems depleted of protein disulphide isomerase.

1990 • 31 citations

Protein disulfide-isomerase retains procollagen prolyl 4-hydroxylase structure in its native conformation

1986 • 29 citations

The transcription and translation in vitro of individual cereal storage-protein genes from wheat (Triticum aestivum, cv. Chinese Spring). Evidence for translocation of the translation products and disulphide-bond formation

1988 • 28 citations

Biosynthesis of prolyl hydroxylase: evidence for two separate dolichol-mediated pathways of glycosylation

1985 • 26 citations

Early disulfide bond formation prevents heterotypic aggregation of membrane proteins in a cell-free translation system.

1992 • 24 citations

Dissociation and reassociation of prolyl 4-hydroxylase subunits after cross-linking of monomers

1981 • 19 citations

Source of heterogeneity in secreted interferon-γ. A study on products of translation in vitro

1990 • 15 citations