Human 17 β-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Oxidized Redox State of Glutathione in the Endoplasmic Reticulum

1992 • 1,909 citations

Intracrinology

1991 • 654 citations

Male pseudohermaphroditism caused by mutations of testicular 17β–hydroxysteroid dehydrogenase 3

1994 • 561 citations

Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity

1993 • 433 citations

Complete amino acid sequence of human placental 17β‐hydroxysteroid dehydrogenase deduced from cDNA

1988 • 298 citations

Aromatase, 17β-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women

1986 • 249 citations

Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 å resolution

1995 • 236 citations

Importance of estrogen sulfates in breast cancer

1989 • 230 citations

Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues

1992 • 228 citations

17 beta-Hydroxysteroid dehydrogenase type 2: chromosomal assignment and progestin regulation of gene expression in human endometrium.

1994 • 209 citations

The 5′ Untranslated Sequence of the c-sis/Platelet-Derived Growth Factor 2 Transcript Is a Potent Translational Inhibitor

1988 • 180 citations

Estradiol and 20α-Dihydroprogesterone Dehydrogenase Activities in Human Endometrium During the Menstrual Cycle

1974 • 177 citations

Structure of Two in Tandem Human 17β-Hydroxysteroid Dehydrogenase Genes

1990 • 176 citations

Immunological analysis of 17β‐hydroxysteroid dehydrogenase in benign and malignant human breast tissue

1992 • 116 citations

Estrone and estradiol content in human breast tumors: Relationship to estradiol receptors

1977 • 105 citations

Regulation of the Gene for Estrogenic 17-Ketosteroid Reductase Lying on Chromosome 17cen→q25

1989 • 99 citations

A comparison of thein vivo uptake and metabolism of3H-oestrone and3H-oestradiol by normal breast and breast tumour tissues in post-menopausal women

1986 • 93 citations

Compartmentalization of type 117β-hydroxysteroid oxidoreductase in the human ovary

1994 • 82 citations

Site-directed mutagenesis of the putative active site of human 17β-hydroxysteroid dehydrogenase type 1

1994 • 79 citations

17 beta-hydroxysteroid dehydrogenase gene expression in human breast cancer cells: regulation of expression by a progestin.

1992 • 77 citations

Rat 17 beta-hydroxysteroid dehydrogenase type 1: primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotropins in vivo.

1994 • 75 citations

Immunohistochemical localization of 17 beta-hydroxysteroid dehydrogenase in the human endometrium during the menstrual cycle.

1991 • 64 citations

Steroidal regulation of oestradiol-17β dehydrogenase activity of the human breast cancer cell line MCF-7

1988 • 62 citations

Changes in the in vitro metabolism of estradiol by human endometrium during the menstrual cycle

1972 • 57 citations

Novel aspects of hormone action: Intracellular ligand supply and its control by a series of tissue specific enzymes

1992 • 46 citations

Regulation of estradiol 17 beta-hydroxysteroid dehydrogenase expression and activity by retinoic acid in T47D breast cancer cells.

1994 • 42 citations

Expression of 17β-hydroxysteroid dehydrogenase in the rat ovary during follicular development and luteinization induced with pregnant mare serum gonadotrophin and human chorionic gonadotrophin

1994 • 40 citations

17β-estradiol dehydrogenase (E2DH) activity in T47D cells

1991 • 29 citations

Enzymatic regulation of estradiol-17β concentrations in human breast cancer cells

1991 • 24 citations

Human Placental 17β-Estradiol Dehydrogenase. VI. Substrate Specificity of the Diphosphopyridine Nucleotide (Triphosphopyridine Nucleotide)-Linked Enzyme1

1971 • 23 citations

Human skin androgen metabolism and preliminary evidence for its control by two forms of 17β-hydroxysteroid oxidoreductase

1982 • 22 citations

Characterization of 17β-hydroxysteroid dehydrogenase type 1 in choriocarcinoma cells: regulation by basic fibroblast growth factor

1994 • 21 citations

Oestradiol-17β hydroxysteroid dehydrogenase: its family and function

1991 • 21 citations

Time-resolved immunofluorometric assay of 17 beta-hydroxysteroid dehydrogenase in plasma

1991 • 14 citations