A human parvovirus, adeno-associated virus, as a eucaryotic vector: transient expression and encapsidation of the procaryotic gene for chloramphenicol acetyltransferase.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Enhancement of the Infectivity of Simian Virus 40 Deoxyribonucleic Acid With Diethylaminoethyl-Dextran<xref ref-type="fn" rid="FN2">2</xref>

1968 • 781 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Nucleotide sequence and organization of the adeno-associated virus 2 genome

1983 • 716 citations

Vaccinia virus: a selectable eukaryotic cloning and expression vector.

1982 • 663 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

A simple method for the preparation of large quantities of pure plasmid DNA

1975 • 586 citations

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

1984 • 520 citations

Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.

1982 • 506 citations

Nucleotide sequence analysis of the chloramphenicol resistance transposon Tn9

1979 • 494 citations

A simple method to recover intact high molecular weight RNA and DNA after electrophoretic separation in low gelling temperature agarose gels

1979 • 460 citations

Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells.

1982 • 456 citations

Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product

1982 • 454 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Extraction of nucleic acids from agarose gels

1980 • 346 citations

Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection.

1983 • 295 citations

Integration of the adeno-associated virus genome into cellular DNA in latently infected human Detroit 6 cells

1980 • 293 citations

Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function

1984 • 279 citations

Cloning of infectious adeno-associated virus genomes in bacterial plasmids

1983 • 276 citations

cis and trans activation of globin gene transcription in transient assays.

1983 • 257 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

1981 • 237 citations

Initiation of translation at internal AUG codons in mammalian cells

1984 • 231 citations

Concatemers of alternating plus and minus strands are intermediates in adenovirus-associated virus DNA synthesis.

1976 • 204 citations

Definition of a novel promoter for the major adenovirus-associated virus mRNA

1980 • 187 citations

Cis-acting induction of adenovirus transcription

1983 • 180 citations

Eukaryotic viral vectors

1982 • 177 citations

E1A Control of Gene Expression Is Mediated by Sequences 5′ to the Transcriptional Starts of the Early Viral Genes

1983 • 169 citations

Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.

1984 • 167 citations

Functional Analysis of Adenovirus-5 Host-range Deletion Mutants Defective for Transformation of Rat Embryo Cells

1980 • 162 citations

Transcriptional Activation and Subsequent Control of the Human Heat Shock Gene During Adenovirus Infection

1983 • 131 citations

Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species

1981 • 123 citations

A cascade of adenovirus early functions is required for expression of adeno-associated virus

1981 • 122 citations

Adeno-associated virus autointerference

1979 • 116 citations

Spliced adenovirus-associated virus RNA.

1979 • 115 citations

Eukaryotic viral vectors

1987 • 96 citations

Locations of adenovirus genes required for the replication of adenovirus-associated virus.

1981 • 91 citations

Mapping of the 5' termini of two adeno-associated virus 2 RNAs in the left half of the genome

1982 • 89 citations

Establishment and characterization of KB cell lines latently infected with adeno-associated virus type 1

1977 • 88 citations

Eukaryotic translational control: adeno-associated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein.

1981 • 82 citations

Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus

1982 • 80 citations

Lethal action of bacteriophage lambda S gene

1982 • 78 citations

Molecular cloning of adeno-associated virus variant genomes and generation of infectious virus by recombination in mammalian cells.

1984 • 64 citations

Properties of an adenovirus type 2 mutant, Ad2d/807, having a deletion near the right-hand genome terminus: Failure to help AAV replication

1983 • 56 citations

Cloning Vectors Derived from Animal Viruses

1983 • 54 citations

Regulation of adenovirus transcription by an E1a gene in microinjected Xenopus laevis oocytes.

1983 • 52 citations

Adeno‐Associated Virus RNA Transcription in vivo

1981 • 51 citations

Adeno-associated virus replication. The effect of L-canavanine or a helper virus mutation on accumulation of viral capsids and progeny single-stranded DNA.

1981 • 38 citations

Construction of Chimeric Phages and Plasmids Containing the Origin of Replication of Bacteriophage Lambda

1977 • 37 citations

Chromatin-like structure of adeno-associated virus DNA in infected cells

1983 • 35 citations

Adeno-Associated Virus Defectiveness and the Nature of the Adenovirus Helper Function

1984 • 28 citations

Construction of an SV40-derived cloning vector

1980 • 24 citations

NUCLEOTIDE SEQUENCE ANALYSIS OF THE CHLORAMPHENICOL RESISTANCE TRANSPOSON Tn9

1980 • 18 citations

Vectors for introducing genes into cells of higher eukaryotes

1983 • 18 citations

Parvovirus Transcription

1984 • 6 citations