Adeno-Associated Virus Defectiveness and the Nature of the Adenovirus Helper Function

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Are snRNPs involved in splicing?

1980 • 1,206 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

Adenovirus-Associated Defective Virus Particles

1965 • 920 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

DNA Tumor Viruses

1982 • 550 citations

Studies of small DNA viruses found in various adenovirus preparations: physical, biological, and immunological characteristics.

1966 • 516 citations

Identification of a protein linked to the ends of adenovirus DNA

1977 • 502 citations

New views of the biochemistry of eucaryotic DNA replication revealed by aphidicolin, an unusual inhibitor of DNA polymerase α

1981 • 389 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Herpes Simplex Virus Types 1 and 2 Completely Help Adenovirus-Associated Virus Replication

1981 • 338 citations

Studies on In Vitro Transformation by DNA and DNA Fragments of Human Adenoviruses and Simian Virus 40

1974 • 334 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

Integration of the adeno-associated virus genome into cellular DNA in latently infected human Detroit 6 cells

1980 • 293 citations

The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets

1981 • 290 citations

Comprehensive Virology

1976 • 288 citations

Palindromic base sequences and replication of eukaryote chromosome ends

1974 • 280 citations

Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing

1981 • 261 citations

DNA replication and the early to late transition in adenovirus infection

1980 • 248 citations

Rolling hairpin model for replication of parvovirus and linear chromosomal DNA

1976 • 240 citations

DNA polymerase of mitochondria is a gamma-polymerase.

1977 • 238 citations

Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

1981 • 237 citations

Transcripts from the adenovirus-2 major late promoter yield a single early family of 3′ coterminal mRNAs and five late families

1980 • 235 citations

Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovrius defective in viral DNA synthesis

1975 • 231 citations

Identification of the gene and mRNA for the adenovirus terminal protein precursor

1981 • 227 citations

A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2

1976 • 216 citations

Involvement of DNA polymerase alpha in simian virus 40 DNA replication.

1978 • 214 citations

The structure of replicating adenovirus 2 DNA molecules

1977 • 210 citations

The initiation sites for RNA transcription in Ad2 DNA

1977 • 208 citations

Replication of Mitochondrial DNA. Circular Replicative Intermediates in Mouse L Cells

1972 • 205 citations

Concatemers of alternating plus and minus strands are intermediates in adenovirus-associated virus DNA synthesis.

1976 • 204 citations

Replication of Mammalian Parvoviruses

1978 • 198 citations

Structural proteins of adenoviruses

1967 • 192 citations

Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands.

1980 • 190 citations

Enhancement of Adenovirus Growth in African Green Monkey Kidney Cell Cultures by SV40

1964 • 190 citations

Definition of a novel promoter for the major adenovirus-associated virus mRNA

1980 • 187 citations

Role of DNA-Dependent RNA Polymerases II and III in Transcription of the Adenovirus Genome Late in Productive Infection

1974 • 186 citations

Regulation of the Primary Expression of the Early Adenovirus Transcription Units

1979 • 184 citations

Control of adenovirus early gene expression: A class of immediate early products

1980 • 182 citations

Adenovirus 5 DNA sequences present and RNA sequences transcribed in transformed human embryo kidney cells (HEK-Ad-5 or 293)

1979 • 176 citations

[74] Microinjection of early SV40 DNA fragments and T antigen

1980 • 176 citations

Involvement of eucaryotic deoxyribonucleic acid polymerases .alpha. and .gamma. in the replication of cellular and viral deoxyribonucleic acid

1979 • 171 citations

Mutations that allow human Ad2 and Ad5 to express late genes in monkey cells map in the viral gene encoding the 72K DNA binding protein

1979 • 170 citations

Nomenclature of Eukaryotic DNA Polymerases

1975 • 168 citations

Replication of the Parvovirus MVM I. Dependence of Virus Multiplication and Plaque Formation on Cell Growth

1972 • 167 citations

Functional Analysis of Adenovirus-5 Host-range Deletion Mutants Defective for Transformation of Rat Embryo Cells

1980 • 162 citations

Structural proteins of adenoviruses

1973 • 161 citations

Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2.

1980 • 157 citations

Detection of adeno-associated virus (AAV)-specific nucleotide sequences in DNA isolated from latently infected Detroit 6 cells

1975 • 152 citations

Effect of 2′, 3′-dideoxythymidine-5′-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase α is the only polymerase required for cellular DNA replication

1978 • 145 citations

The mechanism of interference between an avion leukosis virus and rous sarcoma virus

1966 • 144 citations

Regulation of early adenovirus transcription: A protein product of early region 2 specifically represses region 4 transcription

1980 • 141 citations

A SEROEPIDEMIOLOGIC STUDY OF ADENOVIRUS-ASSOCIATED VIRUS INFECTION IN INFANTS AND CHILDREN

1971 • 130 citations

Loop structures in hybrids of early RNA and the separated strands of adenovirus DNA.

1977 • 126 citations

Chick-Embryo DNA Polymerase gamma. Identity of gamma-Polymerases Purified from Nuclei and Mitochondria

1977 • 125 citations

Physical Assay and Growth Cycle Studies of a Defective Adeno-Satellite Virus

1967 • 124 citations

Possible role of the 72,000 dalton DNA-binding protein in regulation of adenovirus type 5 early gene expression

1978 • 124 citations

An altered subunit configuration associated with the actively transcribed DNA of integrated adenovirus genes

1977 • 124 citations

Comprehensive virology

1975 • 123 citations

Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species

1981 • 123 citations

A cascade of adenovirus early functions is required for expression of adeno-associated virus

1981 • 122 citations

Structure of the linkage between adenovirus DNA and the 55,000 molecular weight terminal protein

1981 • 118 citations

Isolation of adenovirus-associated viruses from man.

1967 • 116 citations

Adeno-associated virus autointerference

1979 • 116 citations

Location of additional early gene sequences in the adenoviral chromosome

1979 • 115 citations

Spliced adenovirus-associated virus RNA.

1979 • 115 citations

Mechanism for RNA splicing of gene transcripts

1979 • 114 citations

Characterization of adenovirus-associated virus-induced polypeptides in KB cells

1978 • 113 citations

Viral nucleic acid sequences in transformed cells

1976 • 112 citations

Block to multiplication of adenovirus serotype 2 in monkey cells

1975 • 111 citations

The functional roles of mammalian DNA polymerase

1979 • 106 citations

Assembly of adeno-associated virus

1980 • 101 citations

Ultraviolet mapping of the adenovirus 2 early promoters

1977 • 100 citations

Association of 20-Millimicron Particles with Adenoviruses

1965 • 100 citations

Replication Process of the Parvovirus H-1 I. Kinetics in a Parasynchronous Cell System

1973 • 98 citations

Multiple mRNA species for the precursor to an adenovirus-encoded glycoprotein: identification and structure of the signal sequence.

1980 • 98 citations

A short description of the adenovirus group

1963 • 98 citations

Studies on the relationship between adeno-associated virus type I (AAV-1) and adenoviruses

1967 • 97 citations

Effect of Cell Physiological State on Infection by Rat Virus

1969 • 97 citations

A Circular DNA-Protein Complex from Adenoviruses and Its Possible Role in DNA Replication

1974 • 96 citations

Incomplete splicing and deficient accumulation of the fiber messenger RNA in monkey cells infected by human adenovirus type 2

1980 • 95 citations

Effect of Cycloheximide on RNA Metabolism Early in Productive Infection with Adenovirus 2

1974 • 94 citations

Identity of DNA Polymerase γ from Synaptosomal Mitochondria and Rat‐Brain Nuclei

1977 • 94 citations

Inhibition of adenovirus-transformed cell oncogenicity by adeno-associated virus

1981 • 91 citations

Locations of adenovirus genes required for the replication of adenovirus-associated virus.

1981 • 91 citations

Mapping of the 5' termini of two adeno-associated virus 2 RNAs in the left half of the genome

1982 • 89 citations

Establishment and characterization of KB cell lines latently infected with adeno-associated virus type 1

1977 • 88 citations

The effect of aphidicolin on adenovirus DNA synthesis

1979 • 84 citations

Oncogenicity of the Simian Adenoviruses

1965 • 84 citations

Deletion mutants of adenovirus 2: Isolation and initial characterization of virus carrying mutations near the right end of the viral genome

1981 • 83 citations

Identification of the adenovirus early proteins and their genomic map positions

1980 • 83 citations

Eukaryotic translational control: adeno-associated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein.

1981 • 82 citations

Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus

1982 • 80 citations

Oncogenic Transformation of Hamster Embryo Cells in vitro by Adenovirus Type 5

1973 • 78 citations

Adenovirus helper function for growth of adeno-associated virus: effect of temperature-sensitive mutations in adenovirus early gene region 2

1980 • 78 citations

Adenovirus-Associated Virus Multiplication VII. Helper Requirement for Viral Deoxyribonucleic Acid and Ribonucleic Acid Synthesis

1972 • 78 citations

An adenovirus mutant defective in splicing RNA from early region 1A

1981 • 78 citations

Arrangement of messenger RNAs and protein coding sequences in the major late transcription unit of adenovirus 2

1980 • 76 citations

Binding of adenovirus VA RNA to mRNA: a possible role in splicing?

1980 • 76 citations

Early Ad-2 transcription units: Only promoter-proximal RNA continues to be made in the presence of DRB

1979 • 75 citations

Influence of Adeno-associated Satellite Virus on Adenovirus-induced Tumours in Hamsters

1973 • 75 citations

Detection of adenovirus type 2-induced early polypeptides using cycloheximide pretreatment to enhance viral protein synthesis

1976 • 75 citations

Defective-interfering particles of the human parvovirus adeno-associated virus

1979 • 75 citations

Replication of adenovirus DNA-protein complex with purified proteins.

1981 • 75 citations

The role of herpesviruses in adenovirus-associated virus replication in vitro

1970 • 73 citations

Inhibition of Adenovirus Oncogenicity in Hamsters by Adeno-Associated Virus DNA<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1981 • 73 citations

Early viral proteins in HeLa cells infected with adenovirus type 5 host range mutants

1980 • 72 citations

Viral transcription in KB cells infected by temperature-sensitive "early" mutants of adenovirus type 5

1976 • 70 citations

Inhibition of Adenovirus 12 Oncogenicity by Adeno-Associated Virus

1968 • 69 citations

Transcripts of the adeno-associated virus genome: mapping of the major RNAs

1980 • 69 citations

Transcription of tRNA genes in vivo: single-stranded compared to double-stranded templates.

1980 • 68 citations

Studies on the relationship between adeno-associated virus type 1 (AAV-1) and adenoviruses

1967 • 67 citations

Covalent association of protein with replicative form DNA of parvovirus H-1.

1979 • 66 citations

Role of DNA polymerase γ in adenovirus DNA replication

1978 • 66 citations

Post-transcriptional restriction of human adenovirus expression in monkey cells

1975 • 61 citations

DNA-Minus Temperature-Sensitive Mutants of Adenovirus Type 5 Help Adenovirus-Associated Virus Replication

1976 • 60 citations

Degradation of intracellular DNA in KB cells infected with cyt mutants of human adenovirus type 12

1981 • 60 citations

Molecular structure of adeno-associated virus variant DNA.

1980 • 60 citations

Adenovirus early gene products may control viral mRNA accumulation and translation in vivo

1981 • 58 citations

Properties of an adenovirus type 2 mutant, Ad2d/807, having a deletion near the right-hand genome terminus: Failure to help AAV replication

1983 • 56 citations

Cell cycle-dependent replication of the DNA of minute virus of mice, a parvovirus

1980 • 56 citations

Isolation of a variant of human adenovirus serotype 2 that multiplies efficiently on monkey cells

1977 • 55 citations

Adenovirus-Associated Virus Multiplication IX. Extent of Transcription of the Viral Genome In Vivo

1972 • 53 citations

Isolation and characterization of adenovirus type 12 DNA binding proteins

1975 • 52 citations

The multiplication of parvovirus Lu III in a synchronized culture system

1973 • 52 citations

Adeno‐Associated Virus RNA Transcription in vivo

1981 • 51 citations

Enzymatic properties of viral replication complexes isolated from adenovirus type 2-infected HeLa cell nuclei

1977 • 50 citations

Replication process of the parvovirus H-1 V. Isolation and characterization of temperature-sensitive H-1 mutants

1976 • 50 citations

Adeno-associated virus DNA replication complexes in herpes simplex virus or adenovirus-infected cells.

1979 • 50 citations

Adenovirus DNA replication in vitro: a protein linked to the 5' end of nascent DNA strands

1981 • 49 citations

Adenovirus deoxyribonucleic acid replication. Characterization of the enzyme activities of a soluble replication system.

1977 • 49 citations

Organization and Expression of the Left Third of the Genome of Adenovirus

1980 • 49 citations

Effect of protein synthesis inhibitors on viral mRNA's synthesized early in adenovirus type 2 infection

1978 • 49 citations

Purification and characterization of an early protein (E14K) from adenovirus type 2-infected cells

1978 • 47 citations

Metabolism of mRNA from the Transforming Region of Adenovirus 2

1980 • 46 citations

Separate Helper Functions provided by Adenovirus for Adenovirus-associated Virus Multiplication

1973 • 46 citations

IMMUNOFLUORESCENT STUDIES OF THE POTENTIATION OF AN ADENOVIRUS-ASSOCIATED VIRUS BY ADENOVIRUS 7

1967 • 46 citations

Autoregulation of Adenovirus Type 5 Early Gene Expression III. Transcription Studies in Isolated Nuclei

1979 • 45 citations

Adeno-associated Virus DNA Replication

1979 • 42 citations

Adenovirus-Associated Viruses: Enhancement by Human Herpesviruses

1970 • 42 citations

Adenovirus Proteins and Their Messenger RNAs

1979 • 40 citations

Isolation of DNA polymerase gamma from an adenovirus 2 DNA replication complex

1975 • 40 citations

Replication of mitochondrial DNA

1975 • 40 citations

Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping

1980 • 39 citations

Physical map and strand polarity of specific fragments of adenovirus-associated virus DNA produced by endonuclease R-EcoRI

1975 • 39 citations

Adenovirus early region 1b gene function required for rescue of latent adeno-associated virus

1980 • 38 citations

Adeno-associated virus replication. The effect of L-canavanine or a helper virus mutation on accumulation of viral capsids and progeny single-stranded DNA.

1981 • 38 citations

Nonencapsidated Infectious DNA of Adeno-Satellite Virus in Cells Coinfected with Herpesvirus

1971 • 37 citations

Transcription of adenovirus RNA in permissive and nonpermissive infections

1978 • 36 citations

The DNA polymerases associated with the adenovirus type 2 replication complex: effect of 2′-3′-dideoxythymidine-5′-triphosphate on viral DNA synthesis

1979 • 36 citations

Analysis of adenovirus 12 temperature-sensitive mutants defective in viral DNA replication

1974 • 35 citations

Adenovirus early function required for protection of viral and cellular DNA

1979 • 35 citations

Synthesis of DNA, late polypeptides, and infectious virus by host-range mutants of adenovirus 5 in nonpermissive cells

1978 • 34 citations

Vero cells injected with adenovirus type 2 mRNA produce authentic viral polypeptide patterns: early mRNA promotes growth of adenovirus-associated virus.

1980 • 34 citations

9 Lytic Infection by Adenoviruses

1980 • 33 citations

Regulation of integrated adenovirus sequences during adenovirus infection of transformed cells

1980 • 33 citations

Inhibition of Adenovirus Transformation in Vitro by AAV-1

1972 • 33 citations

The genomic map position of the adenovirus type 2 glycoprotein

1979 • 32 citations

Heavy and Light Particles of Adeno-Associated Virus

1980 • 30 citations

Adenovirus-Associated Virus Multiplication VIII. Analysis of In Vivo Transcription Induced by Complete or Partial Helper Viruses

1972 • 28 citations

The effects of arginine starvation on macromolecular synthesis in infection with type 2 adenovirus

1972 • 27 citations

The multiplication of parvovirus Lu III in a synchronized culture system

1973 • 27 citations

Isolation of an adeno associated virus from sheep

1979 • 27 citations

Replication Process of the Parvovirus H-1 III. Factors Affecting H-1 RF DNA Synthesis

1974 • 26 citations

Studies of the Enhancement of an Adenovirus-associated Virus by Herpes Simplex Virus

1971 • 26 citations

Adeno-associated Satellite Virus Growth Supported by a Temperature-sensitive Mutant of Human Adenovirus

1970 • 25 citations

Replication process of the parvovirus H-1. X. Isolation of a mutant defective in replicative-form DNA replication

1978 • 23 citations

Physical mapping of adenovirus type 2 temperature-sensitive mutations by restriction endonuclease analysis of interserotypic recombinants

1982 • 22 citations

Complementation of Adeno-Associated Virus Growth with Temperature-Sensitive Mutants of Human Adenovirus Types 12 and 5

1975 • 21 citations

Genome localization of adeno-associated virus RNA

1976 • 21 citations

Comparison of the Passive Haemagglutination and Bentonite Flocculation Tests for Serological Work With Plant Viruses

1968 • 20 citations

Replication of parvoviral DNA. I. Characterization of a nuclear lysate system

1981 • 20 citations

Synthesis of parvovirus H-1 replicative form from viral DNA by DNA polymerase gamma.

1981 • 19 citations

Electron microscope study on the replication of AAV-1 in herpes-infected cells

1972 • 19 citations

Herpesvirus saimiri: Enhancement of Adenovirus-Associated Virus

1973 • 18 citations

Biosynthesis, Immunological Specificity, and Intracellular Distribution of the Simian Virus 40-Specific Protein Induced by the Nondefective Hybrid Ad2 ⁺ ND ₁

1978 • 18 citations

Multiplication of adeno-associated virus type 1 in cells coinfected with A temperature-sensitive mutant of human adenovirus type 31

1976 • 17 citations

Interaction in replication between the goose parvovirus strain B and duck plague herpesvirus

1979 • 16 citations

Adenovirus-associated virus polypeptides synthesized in cells coinfected with either adenovirus or herpesvirus

1979 • 16 citations

Mechanism of Host Restriction of Adenovirus-associated Virus Replication in African Green Monkey Kidney Cells

1979 • 16 citations

Levels of cellular DNA polymerases in synchronized bovine paravovirus-infected cells

1978 • 14 citations

A small virus associated with the simian adenovirus SV11

1966 • 14 citations

Complementation of adeno-associated satellite viral antigens and infectious DNA by temperature-sensitive mutants of herpes simplex virus

1974 • 14 citations

Adenovirus-induced inhibition of cellular DNase

1978 • 14 citations

Replication of an adeno-associated virus in canine and human cells with infectious canine hepatitis virus as a "helper"

1967 • 12 citations

Conditionally Defective Helper Adenoviruses and Satellite Virus Replication

1972 • 12 citations

Human adenovirus type 12 as a "helper" for growth of H-1 virus

1968 • 12 citations

The potentiation of type 1 adeno-associated virus by temperature-sensitive conditional-lethal mutants of CELO virus at the restrictive temperature

1971 • 12 citations

[Structure and biological characteristics of a small, still unclassified virus].

1965 • 12 citations

Phenotypes of Adenovirus-5 Host-range Mutants for Early-mRNA Synthesis

1980 • 10 citations

Helper factor(s) for growth of adeno-associated virus in cells transformed by adenovirus 12.

1977 • 10 citations

Temperature-Sensitive Formation of the DNA Replication Complex in Adenovirus 31-Infected Cells

1974 • 10 citations

Adeno-associated virus--an extreme state of viral defectiveness.

1979 • 9 citations

Properties of Adeno-associated Virus (Type 1) Replicated in Rodent Cells by Murine Adenovirus

1980 • 9 citations

Complementation of Adeno-Associated Satellite Virus (AAV) by Temperature-Sensitive Mutants of Adenovirus Type 31

1977 • 9 citations

Studies on the defectiveness of adeno-associated virus (AAV) I. Effects of phosphonoacetic acid and 2-deoxy-d-glucose on the replication of AAV

1979 • 7 citations

Patterns and consequences of adenoviral RNA splicing Ex pluribus unum - Ex uno plura

1980 • 7 citations

Isolation of the viral DNA replication complex from adeno-associated virus type 1-infected cells

1977 • 7 citations

アデノウイルス2型のmRNAを注入されたVero細胞は,本物のウイルスポリペプチドパターンを生ずる 初期mRNAは,アデノウイルス・アソシエーテッドウイルスの成長を促進する

1980 • 7 citations

Adenovirus-Associated (Satellite) Viruses

2015 • 6 citations

Analysis of Cloned mRNA Sequences from the Transforming Region of Adenovirus 2

1980 • 5 citations

Viral DNA synthesis in vitro with nuclei isolated from adeno-associated virus type 1-infected cells

1977 • 5 citations

Growth of adeno-associated satellite virus under conditions of arginine deprivation

1975 • 4 citations

[Helper viruses of adeno-associated virus type 4 replication].

1979 • 1 citations

WORKSHOP #3 SUMMARY: ADENOVIRUSES/SV40/POLYOMA II

1980 • 1 citations

Deleted Work

1955 • 0 citations