The Trithorax-mimic Allele of Enhancer of zeste Renders Active Domains of Target Genes Accessible to Polycomb-Group-Dependent Silencing in Drosophila melanogaster

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

Drosophila — A Practical Approach

1987 • 1,888 citations

Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes

2000 • 847 citations

Stabilization of Chromatin Structure by PRC1, a Polycomb Complex

1999 • 794 citations

The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes.

1994 • 560 citations

Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors

1991 • 468 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

A group of genes controlling the spatial expression of the bithorax complex in Drosophila

1985 • 413 citations

The Trithorax-like gene encodes the Drosophila GAGA factor

1994 • 409 citations

Imprinting a determined state into the chromatin of Drosophila

1990 • 391 citations

A gene product required for correct initiation of segmental determination in Drosophila

1981 • 361 citations

Molecular and Genetic Organization of The Antennapedia Gene Complex of Drosophila melanogaster

1990 • 360 citations

Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster.

1992 • 335 citations

THE BITHORAX COMPLEX

1987 • 326 citations

Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function.

1993 • 319 citations

Elements of the Drosophila Bithorax Complex That Mediate Repression by Polycomb Group Products

1993 • 317 citations

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis

1990 • 291 citations

The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes

1998 • 287 citations

The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3

2001 • 269 citations

POLYCOMBLIKE: A GENE THAT APPEARS TO BE REQUIRED FOR THE NORMAL EXPRESSION OF THE BITHORAX AND ANTENNAPEDIA GENE COMPLEXES OF DROSOPHILA MELANOGASTER

1982 • 258 citations

Chromatin-associated Protein Phosphatase 1 Regulates Aurora-B and Histone H3 Phosphorylation

2001 • 246 citations

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

1998 • 245 citations

Epigenetic Inheritance of Active Chromatin After Removal of the Main Transactivator

1999 • 239 citations

Mammalian Trithorax and Polycomb -group homologues are antagonistic regulators of homeotic development

1999 • 235 citations

The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax.

1993 • 235 citations

A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.

1990 • 225 citations

The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex.

1995 • 225 citations

Differences in the Interaction of Heparin with Arginine and Lysine and the Importance of these Basic Amino Acids in the Binding of Heparin to Acidic Fibroblast Growth Factor

1995 • 219 citations

DEVELOPMENTAL ANALYSIS OF THE WING DISC IN THE MUTANT ENGRAILED OF DROSOPHILA MELANOGASTER

1972 • 212 citations

Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster.

1990 • 209 citations

A Polycomb and GAGA Dependent Silencer Adjoins the Fab-7 Boundary in the Drosophila Bithorax Complex

1997 • 202 citations

In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element

1990 • 202 citations

The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo

1998 • 198 citations

The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains.

1990 • 196 citations

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb.

1992 • 193 citations

A Screen for New Trithorax Group Genes Identified little imaginal discs, the Drosophila melanogaster Homologue of Human Retinoblastoma Binding Protein 2

2000 • 192 citations

Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression

2001 • 183 citations

Binding of Trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis

1998 • 179 citations

The iab-7 Polycomb Response Element Maps to a Nucleosome-Free Region of Chromatin and Requires Both GAGA and Pleiohomeotic for Silencing Activity

2001 • 178 citations

The MCP silencer of theDrosophila Abd-Bgene requires both Pleiohomeotic and GAGA factor for the maintenance of repression

2001 • 152 citations

The Polycomb group — no longer an exclusive club?

2001 • 150 citations

A Drosophila ESC-E(Z) Protein Complex Is Distinct from Other Polycomb Group Complexes and Contains Covalently Modified ESC

2000 • 150 citations

The Polycomb Group Protein Complex of Drosophila melanogaster Has Different Compositions at Different Target Genes

1997 • 147 citations

The function of engrailed and the specification of Drosophila wing pattern

1995 • 146 citations

Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced.

1995 • 144 citations

A Domain Shared by the Polycomb Group Proteins Scm and ph Mediates Heterotypic and Homotypic Interactions

1997 • 139 citations

Chromatin-silencing mechanisms in Drosophila maintain patterns of gene expression

1997 • 137 citations

The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related.

1989 • 130 citations

The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution

1996 • 129 citations

The trithorax Group Gene moira Encodes a Brahma-Associated Putative Chromatin-Remodeling Factor in Drosophila melanogaster

1999 • 121 citations

Mechanisms of heritable gene repression during development of Drosophila

1993 • 113 citations

Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes.

1990 • 110 citations

The Drosophila esc and E(z) Proteins Are Direct Partners in Polycomb Group-Mediated Repression

1998 • 110 citations

A role of polycomb group genes in the regulation of gap gene expression in Drosophila.

1994 • 108 citations

Trithorax- and Polycomb-Group Response Elements within an Ultrabithorax Transcription Maintenance Unit Consist of Closely Situated but Separable Sequences

1999 • 106 citations

Recruitment of components of Polycomb Group chromatin complexes in Drosophila

2001 • 101 citations

Function of the Polycomb protein is conserved in mice and flies

1995 • 100 citations

E(z): a polycomb group gene or a trithorax group gene?

1996 • 100 citations

Site-Specific Recognition of a 70-Base-Pair Element Containing d(GA)_n Repeats Mediatesbithoraxoid Polycomb Group Response Element-Dependent Silencing

2001 • 96 citations

The Drosophila Polycomb Group proteins ESC and E(Z) bind directly to each other and co-localize at multiple chromosomal sites

1998 • 95 citations

Enhancer Point Mutation Results in a Homeotic Transformation in Drosophila

1994 • 92 citations

Transvection in the Drosophila Abd-B Domain: Extensive Upstream Sequences Are Involved in Anchoring Distant cis-Regulatory Regions to the Promoter

1998 • 88 citations

The Additional sex combs gene of Drosophila is required for activation and repression of homeotic loci, and interacts specifically with Polycomb and super sex combs

1999 • 87 citations

The Drosophila Polycomb Group Protein Psc Contacts ph and Pc through Specific Conserved Domains

1998 • 86 citations

Homeosis and the interaction of zeste and white in Drosophila

1989 • 85 citations

Molecular characterization of the trithorax gene, a positive regulator of homeotic gene expression in Drosophila

1991 • 82 citations

Hunchback-independent silencing of late Ubx enhancers by a Polycomb Group Response Element.

1996 • 80 citations

Mutations in the protein phosphatase 1 gene at 87B can differentially affect suppression of position-effect variegation and mitosis in Drosophila melanogaster.

1993 • 75 citations

In Vivo Chromatin Accessibility Correlates With Gene Silencing in Drosophila

1998 • 73 citations

Genetic interactions and dosage effects of Polycomb group genes of Drosophila

1995 • 67 citations

Suppressor mutation of position-effect variegation in Drosophila melanogaster affecting chromatin properties

1986 • 62 citations

Regulation of polyhomeotic transcription may involve local changes in chromatin activity in Drosophila

1995 • 59 citations

Modifiers of position-effect variegation in the region from 86C to 88B of the Drosophila melanogaster third chromosome

1987 • 51 citations

Interactions of polyhomeotic with Polycomb group genes of Drosophila melanogaster.

1994 • 49 citations

The Genetics and Molecular Biology of zeste in Drosophila melanogaster

1991 • 42 citations

Butyrate sensitive suppressor of position-effect variegation mutations in drosophila melanogaster

1982 • 41 citations

Changes of zeste phenotype induced by autosomal mutations in Drosophila melanogaster

2009 • 40 citations

A novel member of murine Polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro

1999 • 40 citations

Young Garment Workers in Bangladesh: Raising the rights question

2001 • 32 citations

Time out: developmental regulation of heterochromatic silencing in Drosophila

1998 • 18 citations

Reduced phosphotyrosine binding by the v-Src SH2 domain is compatible with wild-type transformation.

1996 • 16 citations

Mutational Dissection of Imaginal Disc Development inDrosophila melanogaster

1977 • 14 citations