Site-Specific Recognition of a 70-Base-Pair Element Containing d(GA)_n Repeats Mediatesbithoraxoid Polycomb Group Response Element-Dependent Silencing

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

Stabilization of Chromatin Structure by PRC1, a Polycomb Complex

1999 • 794 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

Molecular Genetics of the Bithorax Complex in Drosophila melanogaster

1983 • 616 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts

1988 • 454 citations

The Trithorax-like gene encodes the Drosophila GAGA factor

1994 • 409 citations

The Drosophila Polycomb Group Gene pleiohomeotic Encodes a DNA Binding Protein with Homology to the Transcription Factor YY1

1998 • 400 citations

Vectors for P-Mediated Transformation in Drosophila

1988 • 399 citations

Modularity in promoters and enhancers

1989 • 366 citations

A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.

1994 • 346 citations

Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster.

1992 • 335 citations

THE BITHORAX COMPLEX

1987 • 326 citations

Elements of the Drosophila Bithorax Complex That Mediate Repression by Polycomb Group Products

1993 • 317 citations

Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products

1992 • 292 citations

Locking in stable states of gene expression: transcriptional control during Drosophila development

1995 • 283 citations

Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila.

1985 • 278 citations

The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3

2001 • 269 citations

A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton

1996 • 256 citations

Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression

1997 • 235 citations

Characterization of drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene

1985 • 229 citations

Structure of a Polycomb Response Element and In Vitro Binding of Polycomb Group Complexes Containing GAGA Factor

2000 • 213 citations

Chromatin Insulator Elements Block the Silencing of a Target Gene by the Drosophila Polycomb Response Element (PRE) but Allow trans Interactions Between PREs on Different Chromosomes

1997 • 205 citations

A Polycomb and GAGA Dependent Silencer Adjoins the Fab-7 Boundary in the Drosophila Bithorax Complex

1997 • 202 citations

polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertions in Drosophila.

1993 • 200 citations

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb.

1992 • 193 citations

The DNA-binding polycomb group protein pleiohomeotic mediates silencing of a Drosophila homeotic gene

1999 • 181 citations

Binding of Trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis

1998 • 179 citations

Vectors: a survey of molecular cloning vectors and their uses.

1988 • 173 citations

Co-operative DNA binding by GAGA transcription factor requires the conserved BTB/POZ domain and reorganizes promoter topology

1999 • 173 citations

Unusual properties of regulatory DNA from the Drosophila engrailed gene: three "pairing-sensitive" sites within a 1.6-kb region.

1994 • 170 citations

Long range repression conferring boundaries of Ultrabithorax expression in the Drosophila embryo.

1991 • 162 citations

The GAGA factor is required in the early Drosophila embryo not only for transcriptional regulation but also for nuclear division

1996 • 160 citations

The Polycomb Group Protein Complex of Drosophila melanogaster Has Different Compositions at Different Target Genes

1997 • 147 citations

Transcriptional activation of Drosphila homeotic genes form distant regulatory elements

1993 • 147 citations

Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced.

1995 • 144 citations

Direct interaction of the Polycomb protein with Antennapedia regulatory sequences in polytene chromosomes of Drosophila melanogaster.

1991 • 142 citations

A Domain Shared by the Polycomb Group Proteins Scm and ph Mediates Heterotypic and Homotypic Interactions

1997 • 139 citations

A-tract bending: insights into experimental structures by computational models 1 1Edited by Dr I. Tinoco

2000 • 133 citations

Silencers in abdominal-B, a homeotic Drosophila gene.

1993 • 130 citations

White gene expression, repressive chromatin domains and homeotic gene regulation in Drosophila

1994 • 126 citations

A complex genetic locus, polyhomeotic, is required for segmental specification and epidermal development in D. melanogaster

1987 • 123 citations

Discrete Polycomb-binding sites in each parasegmental domain of the bithorax complex

1995 • 119 citations

A fragment of engrailed regulatory DNA can mediate transvection of the white gene in Drosophila.

1991 • 114 citations

Comparison of germline mosaics of genes in the Polycomb group of Drosophila melanogaster.

1995 • 112 citations

The N-terminal POZ Domain of GAGA Mediates the Formation of Oligomers That Bind DNA with High Affinity and Specificity

1999 • 108 citations

Sequence-specific transcriptional antirepression of the Drosophila Krüppel gene by the GAGA factor.

1991 • 107 citations

Trithorax- and Polycomb-Group Response Elements within an Ultrabithorax Transcription Maintenance Unit Consist of Closely Situated but Separable Sequences

1999 • 106 citations

Interactions of thePolycomb group of genes with homeotic loci ofDrosophila

1991 • 101 citations

Recruitment of components of Polycomb Group chromatin complexes in Drosophila

2001 • 101 citations

Multiple isoforms of GAGA factor, a critical component of chromatin structure

1997 • 91 citations

Functional Analysis of Repressor Binding Sites in the iab-2 Regulatory Region of the abdominal-A Homeotic Gene

2000 • 91 citations

The Pipsqueak Protein of Drosophila melanogasterBinds to GAGA Sequences through a Novel DNA-binding Domain

1998 • 89 citations

The Drosophila Polycomb Group Protein Psc Contacts ph and Pc through Specific Conserved Domains

1998 • 86 citations

Hunchback-independent silencing of late Ubx enhancers by a Polycomb Group Response Element.

1996 • 80 citations

GAGA factor binding to DNA via a single trinucleotide sequence element

1998 • 78 citations

Chromatin Remodeling Mediated by Drosophila GAGA Factor and ISWI Activates fushi tarazu Gene Transcription In Vitro

1998 • 77 citations

Distinct parasegmental and imaginal enhancers and the establishment of the expression pattern of the Ubx gene.

1995 • 64 citations

DNA distortion and multimerization: novel functions of the glutamine-rich domain of GAGA factor

1999 • 63 citations

The GAGA factor of Drosophila interacts with SAP18, a Sin3‐associated polypeptide

2000 • 60 citations

The Drosophila pipsqueak gene encodes a nuclear BTB-domain-containing protein required early in oogenesis

1996 • 52 citations

Imaginal disc silencers from Ultrabithorax: evidence for Polycomb response elements

1994 • 46 citations

The GAGA Factor of Drosophila Binds Triple-stranded DNA

1998 • 46 citations

pipsqueak encodes a novel nuclear protein required downstream of seven-up for the development of photoreceptors R3 and R4.

1995 • 36 citations

pipsqueak, an early acting member of the posterior group of genes, affects vasa level and germ cell-somatic cell interaction in the developing egg chamber

1993 • 35 citations

The polyhomeotic locus of Drosophila melanogaster is transcriptionally and post-transcriptionally regulated during embryogenesis

1997 • 34 citations

Transposon-induced rearrangements in the duplicated locus ph of Drosophila melanogaster can create new chimeric genes functionally identical to the wild type

1994 • 6 citations