Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1982 • 1,385 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all

1990 • 726 citations

Exon definition may facilitate splice site selection in RNAs with multiple exons.

1990 • 726 citations

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1990 • 692 citations

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1985 • 686 citations

A physical map of the DNA regions flanking the rabbit β-globin gene

1977 • 654 citations

A survey on intron and exon lengths

1988 • 569 citations

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

1987 • 405 citations

Nucleolin, the major nucleolar protein of growing eukaryotic cells: an unusual protein structure revealed by the nucleotide sequence.

1987 • 393 citations

The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.

1992 • 377 citations

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

1991 • 375 citations

Exon Definition May Facilitate Splice Site Selection in RNAs with Multiple Exons

1990 • 269 citations

The Chronic Myelocytic Cell Line K562 Contains a Breakpoint in bcr and Produces a Chimeric bcr/c-abl Transcript

1986 • 192 citations

Detection of the Philadelphia chromosome in interphase nuclei

1990 • 185 citations

Identification and molecular cloning of yeast homolog of nucleosome assembly protein I which facilitates nucleosome assembly in vitro.

1991 • 180 citations

Anionic regions in nuclear proteins.

1987 • 167 citations

A nonsense mutation causing decreased levels of insulin receptor mRNA: detection by a simplified technique for direct sequencing of genomic DNA amplified by the polymerase chain reaction.

1990 • 155 citations

A major soluble acidic protein located in nuclei of diverse vertebrate species

1980 • 131 citations

The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript.

1986 • 128 citations

The translocation (6;9) (p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features

1992 • 109 citations

The (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34.

1990 • 107 citations

Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia

1987 • 102 citations

Expression of human myeloid-associated surface antigens in human-mouse myeloid cell hybrids.

1983 • 67 citations

Immunoglobulin and T-cell receptor gene rearrangements in acute non-lymphocytic leukemias. Analysis of 54 cases and a review of the literature.

1991 • 45 citations

Acute myeloblastic leukemia (AML) with t(6;9) (p23;q34): A specific subgroup of AML?

1983 • 44 citations

Dek-can rearrangement in translocation (6;9)(p23;q34).

1992 • 37 citations

Duplication of thebcrand gamma-glutamyl transpeptidase genes

1988 • 33 citations

Translocation (6;9) may be associated with a specific TdT-positive immunological phenotype in ANLL.

1988 • 27 citations

The human pim-1 gene is not directly activated by the translocation (6;9) in acute nonlymphocytic leukemia.

1989 • 25 citations

Cloning and sequencing of Plasmodiumfalciparum DNA fragments containing repetitive regions potentially coding for histidine-rich proteins: identification of two overlapping reading frames

1987 • 22 citations

The translocation (6;9) (p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features

1992 • 5 citations