Soluble Vascular Cell Adhesion Molecule-1 (VCAM-1) as Potential Marker of Atherosclerosis

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

1991 • 1,703 citations

Selectins and their ligands: current concepts and controversies

1996 • 1,446 citations

Circulating adhesion molecules in disease

1993 • 1,425 citations

Circulating Adhesion Molecules VCAM-1, ICAM-1, and E-selectin in Carotid Atherosclerosis and Incident Coronary Heart Disease Cases

1997 • 1,334 citations

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.

1993 • 1,079 citations

α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1995 • 1,018 citations

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

1998 • 917 citations

Upregulation of VCAM-1 and ICAM-1 at Atherosclerosis-Prone Sites on the Endothelium in the ApoE-Deficient Mouse

1998 • 890 citations

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

1992 • 828 citations

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation

1991 • 796 citations

The expression of the adhesion molecules ICAM‐1, VCAM‐1, PECAM, and E‐selectin in human atherosclerosis

1993 • 772 citations

High-Density Lipoproteins Inhibit Cytokine-Induced Expression of Endothelial Cell Adhesion Molecules

1995 • 759 citations

Expression cloning of a functional glycoprotein ligand for P-selectin

1993 • 734 citations

The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

1995 • 716 citations

Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis.

1993 • 709 citations

A form of circulating ICAM-1 in human serum.

1991 • 700 citations

An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium.

1993 • 680 citations

Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions.

1991 • 669 citations

Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells

1992 • 653 citations

Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1

1995 • 599 citations

Neovascular Expression of E-Selectin, Intercellular Adhesion Molecule-1, and Vascular Cell Adhesion Molecule-1 in Human Atherosclerosis and Their Relation to Intimal Leukocyte Content

1996 • 573 citations

L-selectin-mediated lymphocyte rolling on MAdCAM-1

1993 • 540 citations

E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro.

1992 • 519 citations

The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells.

1994 • 467 citations

Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells.

1995 • 461 citations

Soluble L-selectin is present in human plasma at high levels and retains functional activity.

1992 • 422 citations

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

1995 • 358 citations

Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock.

1993 • 349 citations

Circulating Vascular Cell Adhesion Molecule-1 Correlates With the Extent of Human Atherosclerosis in Contrast to Circulating Intercellular Adhesion Molecule-1, E-Selectin, P-Selectin, and Thrombomodulin

1997 • 311 citations

Circulating intercellular adhesion molecule-1 (ICAM-1), E-selectin and vascular cell adhesion molecule-1 (VCAM-1) in human malignancies

1993 • 296 citations

Thrombomodulin is present in human plasma and urine.

1985 • 295 citations

Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1.

1994 • 282 citations

Soluble Vascular Cell Adhesion Molecule-1 as a Biohumoral Correlate of Atherosclerosis

1997 • 272 citations

Aspirin Inhibits Nuclear Factor–κB Mobilization and Monocyte Adhesion in Stimulated Human Endothelial Cells

1995 • 260 citations

Soluble Cell Adhesion Molecules in Hypertriglyceridemia and Potential Significance on Monocyte Adhesion

1998 • 222 citations

Soluble thrombomodulin as a predictor of incident coronary heart disease and symptomless carotid artery atheroscierosis in the Atherosclerosis Risk in Communities (ARIC) Study: a case-cohort study

1999 • 221 citations

Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4.

1994 • 165 citations

Thrombomodulin structure and function.

1997 • 158 citations

von Willebrand Factor, Soluble P-Selectin, Tissue Plasminogen Activator and Plasminogen Activator Inhibitor in Atherosclerosis

1995 • 145 citations

Detection of a circulating form of vascular cell adhesion molecule-1: raised levels in rheumatoid arthritis and systemic lupus erythematosus

1993 • 139 citations

Detection of increased levels of circulating intercellular adhesion molecule 1 in some patients with rheumatoid arthritis but not in patients with systemic lupus erythematosus. lack of correlation with levels of circulating vascular cell adhesion molecule 1

1993 • 139 citations

Polyclonal origin of T lymphocytes in human atherosclerotic plaques.

1991 • 133 citations

Tissue Inhibitor of Metalloproteinases-3 Inhibits Shedding of L-selectin from Leukocytes

1999 • 126 citations

P-Selectin and Vascular Cell Adhesion Molecule-1 Are Focally Expressed in Aortas of Hypercholesterolemic Rabbits Before Intimal Accumulation of Macrophages and T Lymphocytes

1997 • 119 citations

Expression of a disintegrin‐like protein in cultured human vascular cells and in vivo

1997 • 115 citations

Native low density lipoprotein-induced calcium transients trigger VCAM-1 and E-selectin expression in cultured human vascular endothelial cells.

1998 • 112 citations

Expression of adhesion molecules by Lp(a): a potential novel mechanism for its atherogenicity

1998 • 112 citations

Elevated Levels of Circulating Soluble Adhesion Molecules in Peripheral Blood of Patients With Unstable Angina

1997 • 107 citations

Soluble intercellular adhesion molecule 1 is released by human melanoma cells and is associated with tumor growth in nude mice.

1992 • 102 citations

CORRELATION OF BLOOD LEVELS OF SOLUBLE VASCULAR CELL ADHESION MOLECULE-1 WITH DISEASE ACTIVITY IN SYSTEMIC LUPUS ERYTHEMATOSUS AND VASCULITIS

1994 • 102 citations

Circulating Vascular Cell Adhesion Molecule-1 (VCAM-1) in Atherosclerotic NIDDM Patients

1997 • 100 citations

Adhesion Molecule P-Selectin and Vascular Cell Adhesion Molecule–1 in Enhanced Heart Allograft Arteriosclerosis in the Rat

1997 • 69 citations

Detection of an L-selectin ligand on a hematopoietic progenitor cell line

1994 • 61 citations

Cell Adhesion Molecules: An Overview

1998 • 54 citations

von Willebrand factor and soluble E-selectin in the prediction of cardiovascular disease progression in hyperlipidaemia

1997 • 51 citations

Early temporal expression of soluble cellular adhesion molecules in patients with unstable angina and subendocardial myocardial infarction11This research was aided by a grant from The Royal City of Dublin Hospital (RCDH) Board.

1999 • 46 citations

Increased interleukin-1α and interleukin-1β production by macrophages of low-density lipoprotein receptor knock-out mice stimulated with lipopolysaccharide is CD11c/CD18-receptor mediated

1998 • 18 citations

Increased plasma GlyCAM-1, a mouse L-selectin ligand, in response to an inflammatory stimulus

1996 • 13 citations