Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4.

Adhesion receptors of the immune system

1990 • 6,585 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

1991 • 1,703 citations

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

1988 • 967 citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin.

1989 • 807 citations

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation

1991 • 796 citations

The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus

1990 • 709 citations

Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules.

1991 • 675 citations

An Inducible Endothelial Cell Surface Glycoprotein Mediates Melanoma Adhesion

1989 • 659 citations

Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor α4β1

1990 • 616 citations

Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells [published erratum appears in Blood 1990 Dec 1;76(11):2420]

1990 • 540 citations

Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1.

1991 • 510 citations

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes.

1992 • 437 citations

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

1992 • 417 citations

Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes. A CD11/CD18-independent adhesion mechanism.

1990 • 408 citations

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

1991 • 406 citations

Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis

1992 • 404 citations

A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture.

1991 • 399 citations

The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine

1991 • 362 citations

Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes

1992 • 350 citations

A monoclonal antibody that detects a novel antigen on endothelial cells that is induced by tumor necrosis factor, IL-1, or lipopolysaccharide.

1990 • 339 citations

Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1

1991 • 318 citations

Vascular and nonvascular expression of INCAM-110. A target for mononuclear leukocyte adhesion in normal and inflamed human tissues.

1991 • 306 citations

Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells.

1992 • 303 citations

Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues.

1991 • 295 citations

Adhesion of Human B Cells to Germinal Centers in Vitro Involves VLA-4 and INCAM-110

1990 • 295 citations

Adhesion of human B cells to follicular dendritic cells involves both the lymphocyte function-associated antigen 1/intercellular adhesion molecule 1 and very late antigen 4/vascular cell adhesion molecule 1 pathways.

1991 • 291 citations

Mechanisms of eosinophil adherence to cultured vascular endothelial cells. Eosinophils bind to the cytokine-induced ligand vascular cell adhesion molecule-1 via the very late activation antigen-4 integrin receptor.

1991 • 268 citations

The Expression of Endothelial Leukocyte Adhesion Molecule-1 (ELAM-1), Intercellular Adhesion Molecule-1 (ICAM-1), and Vascular Cell Adhesion Molecule-1 (VCAM-1) in Experimental Cutaneous Inflammation: A Comparison of Ultraviolet B erythema and Delayed Hypersensitivity

1991 • 247 citations

Affinity chromatographic isolation of the melanoma adhesion receptor for the IIICS region of fibronectin and its identification as the integrin alpha 4 beta 1.

1990 • 244 citations

Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells.

1991 • 234 citations

Human eosinophil adherence to vascular endothelium mediated by binding to vascular cell adhesion molecule 1 and endothelial leukocyte adhesion molecule 1.

1991 • 233 citations

VLA‐3: A novel polypeptide association within the VLA molecular complex: cell distribution and biochemical characterization

1986 • 214 citations

Cloning and characterization of a new intercellular adhesion molecule ICAM-R

1992 • 210 citations

Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes.

1992 • 202 citations

Molecules and structures involved in the adhesion of natural killer cells to vascular endothelium.

1991 • 163 citations

Activated endothelium binds lymphocytes through a novel binding site in the alternately spliced domain of vascular cell adhesion molecule-1.

1992 • 163 citations

Identification of surface proteins mediating adherence of CD11/CD18-deficient lymphoblastoid cells to cultured human endothelium.

1990 • 154 citations

Lymphocyte adhesion through very late antigen 4: evidence for a novel binding site in the alternatively spliced domain of vascular cell adhesion molecule 1 and an additional alpha 4 integrin counter-receptor on stimulated endothelium.

1992 • 150 citations

The VLA-4/VCAM-1 pathway is involved in lymphocyte adhesion to endothelium in rheumatoid synovium.

1991 • 147 citations

Activation-dependent recognition by hematopoietic cells of the LDV sequence in the V region of fibronectin.

1992 • 140 citations

Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1.

1991 • 134 citations

Cell adhesion receptor expression during melanoma progression and metastasis

1991 • 125 citations

Cloning of an alternate form of vascular cell adhesion molecule-1 (VCAM1).

1991 • 124 citations

Induced expression of endothelial-leukocyte adhesion molecules in human cardiac allografts.

1991 • 124 citations

Alternative splicing of human VCAM-1 in activated vascular endothelium.

1991 • 123 citations

Isolation of the murine intercellular adhesion molecule 1 (ICAM-1) gene. ICAM-1 enhances antigen-specific T cell activation.

1989 • 118 citations

Cloning and expression of intercellular adhesion molecule 3 reveals strong homology to other immunoglobulin family counter-receptors for lymphocyte function-associated antigen 1.

1993 • 115 citations

Tumor necrosis factor alpha induces adhesion molecule expression on human fetal astrocytes.

1992 • 98 citations

Cloning of murine and rat vascular cell adhesion molecule-1

1992 • 93 citations

Increased binding of synovial T lymphocytes from rheumatoid arthritis to endothelial-leukocyte adhesion molecule-1 (ELAM-1) and vascular cell adhesion molecule-1 (VCAM-1).

1992 • 90 citations

Importance of endothelial VCAM-1 for inflammatory leukocytic infiltration in vivo.

1992 • 86 citations

Expression of vascular cell adhesion molecule-1 in fibroblastlike synoviocytes after stimulation with tumor necrosis factor.

1992 • 85 citations

Induction of VCAM-1 and ICAM-1 on human neural cells and mechanisms of mononuclear leukocyte adherence.

1992 • 76 citations

Full length vascular cell adhesion molecule 1 (VCAM-1)

1990 • 73 citations

Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA.

1992 • 59 citations

Expression of adhesion molecules in human intestinal graft- versus- host disease

1992 • 50 citations

Cloning of an inflammation-specific phosphatidyl inositol-linked form of murine vascular cell adhesion molecule-1.

1993 • 42 citations

Vessel associated adhesion molecules in normal skin and acute graft-versus-host disease.

1991 • 41 citations

Role of beta 1 integrins in tumor cell adhesion to cultured human endothelial cells.

1991 • 33 citations

Soluble intercellular adhesion molecule 1-immunoglobulin G1 immunoadhesin mediates phagocytosis of malaria-infected erythrocytes.

1992 • 26 citations

Adhesion molecule expression in human hepatic graft-versus-host disease.

1992 • 22 citations