Relevance of nucleic acid amplification techniques for diagnosis of respiratory tract infections in the clinical laboratory

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Rapid and simple method for purification of nucleic acids

1990 • 5,273 citations

Specific Enzymatic Amplification of DNA In Vitro: The Polymerase Chain Reaction

1986 • 3,400 citations

Diagnostic molecular microbiology : principles and applications

1993 • 1,331 citations

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis

1993 • 1,307 citations

Nucleic acid sequence-based amplification

1991 • 1,287 citations

Respiratory viruses and exacerbations of asthma in adults.

1993 • 1,126 citations

Essentials of medical statistics.

1988 • 934 citations

A Ligase-Mediated Gene Detection Technique

1988 • 834 citations

Polymerase Chain Reaction Amplification of a Repetitive DNA Sequence Specific for Mycobacterium tuberculosis

1990 • 763 citations

Simple and Rapid Preparation of Samples for PCR

1989 • 596 citations

Ecological distribution of Legionella pneumophila

1981 • 560 citations

Comparison of various repetitive DNA elements as genetic markers for strain differentiation and epidemiology of Mycobacterium tuberculosis

1993 • 488 citations

Genotypic identification of mycobacteria by nucleic acid sequence determination: report of a 2-year experience in a clinical laboratory

1993 • 486 citations

Sensitivity and specificity of PCR for detection of Mycobacterium tuberculosis: a blind comparison study among seven laboratories

1994 • 436 citations

Insertion element IS986 from Mycobacterium tuberculosis: a useful tool for diagnosis and epidemiology of tuberculosis

1990 • 419 citations

Detection of a wide range of medically important fungi by the polymerase chain reaction

1994 • 406 citations

Detection ofMycobacterium tuberculosisin Sputum Samples Using a Polymerase Chain Reaction

1991 • 364 citations

Large-scale use of polymerase chain reaction for detection of Mycobacterium tuberculosis in a routine mycobacteriology laboratory

1993 • 346 citations

Quantitative competitive polymerase chain reaction for accurate quantitation of HIV DNA and RNA species.

1993 • 319 citations

Characterization by automated DNA sequencing of mutations in the gene (rpoB) encoding the RNA polymerase beta subunit in rifampin-resistant Mycobacterium tuberculosis strains from New York City and Texas

1994 • 315 citations

Diagnostic molecular microbiology.

2001 • 305 citations

Evidence that Chlamydia pneumoniae Causes Pneumonia and Bronchitis

1993 • 280 citations

Characterization of rifampin-resistance in pathogenic mycobacteria

1994 • 278 citations

Detection of Chlamydia pneumoniae by polymerase chain reaction

1992 • 262 citations

Use of polymerase chain reaction for diagnosis of picornavirus infection in subjects with and without respiratory symptoms

1993 • 261 citations

Direct, automated detection of rifampin-resistant Mycobacterium tuberculosis by polymerase chain reaction and single-strand conformation polymorphism analysis

1993 • 258 citations

The ligation amplification reaction (LAR)—Amplification of specific DNA sequences using sequential rounds of template-dependent ligation

1989 • 258 citations

Detection and identification of Mycobacterium tuberculosis directly from sputum sediments by amplification of rRNA

1993 • 258 citations

A one-step microbial DNA extraction method using “Chelex 100” suitable for gene amplification

1992 • 239 citations

Specific detection of Mycobacterium tuberculosis complex strains by polymerase chain reaction

1990 • 233 citations

MULTIPLEX PCR FOR THE DIAGNOSIS OF DUCHENNE MUSCULAR DYSTROPHY

1990 • 231 citations

Current knowledge onChlamydia pneumoniae, strain TWAR, an important cause of pneumonia and other acute respiratory diseases

1989 • 226 citations

Rapid detection of rifampicin resistance in sputum and biopsy specimens from tuberculosis patients by PCR and line probe assay

1995 • 225 citations

Detection and identification of Mycobacterium tuberculosis by DNA amplification

1990 • 216 citations

Enzymatic synthesis of deoxyribonucleic acid.

1957 • 215 citations

Hot water systems as sources of Legionella pneumophila in hospital and nonhospital plumbing fixtures

1982 • 209 citations

Detection of Chlamydia pneumoniae and Chlamydia psittaci in sputum samples by PCR.

1993 • 207 citations

Detection of Mycobacterium tuberculosis in clinical specimens by polymerase chain reaction and Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test

1993 • 204 citations

Prevalence of Asymptomatic Nasopharyngeal Carriage of Chlamydia pneumoniae in Subjectively Healthy Adults: Assessment by Polymerase Chain Reaction-Enzyme Immunoassay and Culture

1995 • 202 citations

Identification of Chlamydia pneumoniae by DNA amplification of the 16S rRNA gene

1992 • 201 citations

General primer-mediated PCR for detection of Aspergillus species

1994 • 197 citations

Detection of Aspergillus species DNA in bronchoalveolar lavage samples by competitive PCR

1995 • 197 citations

Identification of a New North American Hantavirus that Causes Acute Pulmonary Insufficiency

1995 • 187 citations

Direct detection of Mycobacterium tuberculosis in sputum by polymerase chain reaction and DNA hybridization

1993 • 183 citations

Reliability of nucleic acid amplification for detection of Mycobacterium tuberculosis: an international collaborative quality control study among 30 laboratories

1996 • 180 citations

Detection of Coxiella burnetti by DNA amplification using polymerase chain reaction

1992 • 173 citations

Characterization of Mycobacterium tuberculosis strains from Vietnamese patients by Southern blot hybridization

1993 • 168 citations

Advances in nucleic acid-based detection methods

1992 • 168 citations

Improved diagnosis of Pneumocystis carinii infection by polymerase chain reaction on induced sputum and blood

1992 • 166 citations

The Detection ofAspergillusspp. by the Polymerase Chain Reaction and Its Evaluation in Bronchoalveolar Lavage Fluid

1993 • 166 citations

Rapid diagnosis of pulmonary tuberculosis by using Roche AMPLICOR Mycobacterium tuberculosis PCR test

1995 • 164 citations

Detection of Mycoplasma pneumoniae by Two Polymerase Chain Reactions and Role of M. pneumoniae in Acute Respiratory Tract Infections in Pediatric Patients

1996 • 160 citations

Progress toward a simplified polymerase chain reaction and its application to diagnosis of tuberculosis

1993 • 157 citations

Direct detection of Mycobacterium tuberculosis in respiratory specimens in a clinical laboratory by polymerase chain reaction

1993 • 157 citations

Diagnostic utility of PCR-enzyme immunoassay, culture, and serology for detection of Chlamydia pneumoniae in symptomatic and asymptomatic patients

1994 • 154 citations

Detection and differentiation of picornaviruses in clinical samples following genomic amplification

1990 • 153 citations

Detection of Aspergillus fumigatus by polymerase chain reaction

1993 • 152 citations

Use of a reamplification protocol improves sensitivity of detection of Mycobacterium tuberculosis in clinical samples by amplification of DNA

1991 • 151 citations

Polymerase Chain Reaction for the Diagnosis of Candidemia

1993 • 148 citations

Evaluation of Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test and PCR for direct detection of Mycobacterium tuberculosis in clinical specimens

1994 • 144 citations

Isolation of 16 strains of Coxiella burnetii from patients by using a sensitive centrifugation cell culture system and establishment of the strains in HEL cells

1990 • 140 citations

Detection and differentiation of fungi in clinical specimens using polymerase chain reaction (PCR) amplification and restriction enzyme analysis

1993 • 140 citations

Nonculture methods for diagnosis of disseminated candidiasis

1993 • 137 citations

Role of Chlamydia trachomatis in Perinatal Infection

1983 • 136 citations

Direct detection of Mycobacterium tuberculosis complex in respiratory specimens by a target-amplified test system

1994 • 136 citations

Detection of Mycobacterium tuberculosis in sputum samples by polymerase chain reaction using a simplified procedure

1993 • 135 citations

Controlled Evaluation of Copper-Silver Ionization in Eradicating Legionella pneumophila from a Hospital Water Distribution System

1994 • 135 citations

Detection of enteroviruses and rhinoviruses in clinical specimens by PCR and liquid-phase hybridization

1995 • 132 citations

Detection of Legionella spp. in bronchoalveolar lavage fluids by DNA amplification

1992 • 130 citations

Clinical evaluation of a Mycobacterium tuberculosis PCR assay

1995 • 129 citations

Primers are decisive for sensitivity of PCR.

1994 • 124 citations

Detection of Mycoplasma pneumoniae and Mycoplasma genitalium in Clinical Samples by Polymerase Chain Reaction

1993 • 123 citations

Detection of Mycobacterium tuberculosis in clinical samples by two-step polymerase chain reaction and nonisotopic hybridization methods

1993 • 121 citations

Rapid detection and identification of Candida albicans and Torulopsis (Candida) glabrata in clinical specimens by species-specific nested PCR amplification of a cytochrome P-450 lanosterol-alpha-demethylase (L1A1) gene fragment

1994 • 120 citations

Amplification of rhinovirus specific nucleic acids from clinical samples using the polymerase chain reaction

1989 • 118 citations

Rapid detection of respiratory syncytial virus in nasopharyngeal aspirates by reverse transcription and polymerase chain reaction amplification

1992 • 116 citations

Direct PCR enables detection of Mycoplasma pneumoniae in patients with respiratory tract infections

1994 • 115 citations

Nested polymerase chain reaction for detection of Mycobacterium tuberculosis in clinical samples

1993 • 113 citations

Detection of Candida albicans and other yeasts in blood by PCR

1994 • 111 citations

Rapid detection and identification of pathogenic mycobacteria by combining radiometric and nucleic acid probe methods

1988 • 110 citations

Polymerase chain reaction assay for pertussis: simultaneous detection and discrimination of Bordetella pertussis and Bordetella parapertussis

1993 • 109 citations

Sequence capture-PCR improves detection of mycobacterial DNA in clinical specimens

1996 • 109 citations

Direct detection of Mycobacterium tuberculosis complex in respiratory specimens by Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test and Roche Amplicor Mycobacterium Tuberculosis Test

1995 • 108 citations

Comparison of polymerase chain reaction, culture, and western immunoblot serology for diagnosis of Bordetella pertussis infection

1993 • 106 citations

Nucleotide sequence of the P1 attachment-protein gene of Mycoplasma pneumoniae

1988 • 106 citations

Detection and identification of Mycobacterium tuberculosis directly from sputum sediments by Amplicor PCR

1995 • 105 citations

The rapid diagnosis of tuberculosis: a selective review.

1990 • 105 citations

Detection and identification of mycobacteria by amplification of a segment of the gene coding for the 32-kilodalton protein

1992 • 105 citations

Quantitation of hepatitis C virus RNA by competitive polymerase chain reaction

1992 • 104 citations

Rapid, simple method for treating clinical specimens containing Mycobacterium tuberculosis to remove DNA for polymerase chain reaction

1992 • 103 citations

Detection of Mycoplasma pneumoniae in clinical samples from pediatric patients by polymerase chain reaction

1992 • 103 citations

Detection of Pneumocystis carinii DNA in sputum and bronchoalveolar lavage samples by polymerase chain reaction

1996 • 103 citations

Application of the polymerase chain reaction to the diagnosis of candidosis by amplification of an HSP 90 gene fragment

1993 • 103 citations

Improved detection of rhinoviruses in nasal and throat swabs by seminested RT‐PCR

1993 • 100 citations

Detection of mycobacterial DNA in pleural fluid from patients with tuberculous pleurisy by means of the polymerase chain reaction: comparison of two protocols.

1992 • 100 citations

Recommendations for use of the polymerase chain reaction in the diagnosis of Bordetella pertussis infections*

1994 • 98 citations

Diagnosis of tuberculosis by Amplicor Mycobacterium tuberculosis test: a multicenter study

1995 • 98 citations

Isolation and characterization of a species-specific DNA fragment for detection of Candida albicans by polymerase chain reaction

1992 • 96 citations

Detection of Mycoplasma pneumoniae by polymerase chain reaction and nonradioactive hybridization in microtiter plates

1993 • 95 citations

Genotypic detection of Mycobacterium tuberculosis rifampin resistance: comparison of single-strand conformation polymorphism and dideoxy fingerprinting

1995 • 94 citations

Detection and Differentiation of Chlamydia trachomatis, Chlamydia psittaci, and Chlamydia pneumoniae by DNA Amplification

1990 • 93 citations

Inhibition of PCR-based assay for Bordetella pertussis by using calcium alginate fiber and aluminum shaft components of a nasopharyngeal swab

1994 • 92 citations

Clinical Utility of the Polymerase Chain Reaction in the Diagnosis of Infections due to Mycobacterium tuberculosis

1994 • 91 citations

Application of DNA fingerprinting with IS986 to sequential mycobacterial isolates obtained from pulmonary tuberculosis patients in Hong Kong before, during and after short-course chemotherapy

1993 • 91 citations

Improved detection of Candida albicans by PCR in blood of neutropenic mice with systemic candidiasis

1995 • 90 citations

Evaluation of nested polymerase chain methods for the detection of human coronaviruses 229E and OC43

1994 • 90 citations

Nucleotide Sequence Comparison of the Mycobacterial dnaJ Gene and PCR-Restriction Fragment Length Polymorphism Analysis for Identification of Mycobacterial Species

1994 • 90 citations

New method for detection of Candida albicans in human blood by polymerase chain reaction

1993 • 88 citations

Evaluation of culture, immunofluorescence, and serology for the diagnosis of pertussis

1989 • 88 citations

Evaluation of Amplicor PCR for direct detection of Mycobacterium tuberculosis from sputum specimens

1995 • 88 citations

Suppression of colds in human volunteers challenged with rhinovirus by a new synthetic drug (R61837)

1989 • 86 citations

Respiratory infection withchalmydia pneumoniae in middle-aged and older adult outpatients

1994 • 85 citations

Diagnostic value of an amplification method (Gen-Probe) compared with that of culture for diagnosis of tuberculosis

1995 • 84 citations

Comparison of polymerase chain reaction with culture and enzyme immunoassay for diagnosis of pertussis

1993 • 83 citations

Diagnosis of Primary Tuberculosis in Children by Amplification and Detection of Mycobacterial DNA

1993 • 82 citations

Q fever pneumonia in children in Japan

1996 • 81 citations

Major outbreak of pertussis in northern Alberta, Canada: analysis of discrepant direct fluorescent-antibody and culture results by using polymerase chain reaction methodology

1993 • 81 citations

Rapid detection of Legionella species in bronchoalveolar lavage fluids with the EnviroAmp Legionella PCR amplification and detection kit

1993 • 80 citations

Screening of respiratory tract specimens for the presence of Mycobacterium tuberculosis by using the Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test

1994 • 80 citations

Comparison of polymerase chain reaction amplification of two mycobacterial DNA sequences, IS6110 and the 65kDa antigen gene, in the diagnosis of tuberculosis.

1992 • 80 citations

Detection of Chlamydia pneumoniae by Polymerase Chain Reaction-Enzyme Immunoassay in an Immunocompromised Population

1993 • 78 citations

Multiplex strand displacement amplification (SDA) and detection of DNA sequences fromMycobacterium tuberculosisand other mycobacteria

1994 • 78 citations

Strand Displacement Amplification and the Polymerase Chain Reaction for Monitoring Response to Treatment in Patients with Pulmonary Tuberculosis

1996 • 78 citations

Amplification of DNA of Mycobacterium tuberculosis from peripheral blood of patients with pulmonary tuberculosis

1994 • 77 citations

Quantitative assays based on the use of replicatable hybridization probes.

1989 • 77 citations

Direct genotypic detection of Mycobacterium tuberculosis rifampin resistance in clinical specimens by using single-tube heminested PCR

1995 • 77 citations

Evaluation of Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test and Roche PCR-microwell plate hybridization method (AMPLICOR MYCOBACTERIUM) for direct detection of mycobacteria

1996 • 76 citations

Comparison of Amplicor, in-house PCR, and conventional culture for detection of Mycobacterium tuberculosis in clinical samples

1995 • 76 citations

Detection of Candida albicans DNA in Serum by Polymerase Chain Reaction

1994 • 74 citations

Evaluation of Roche Amplicor PCR assay for Mycobacterium tuberculosis

1996 • 73 citations

Diagnosis of viral respiratory tract infections in children by using a reverse transcription-PCR panel

1996 • 72 citations

Genus-specific polymerase chain reaction for the mycobacterial dnaJ gene and species-specific oligonucleotide probes

1993 • 71 citations

Use of Self-Sustained Sequence Replication Amplification Reaction to Analyze and Detect Mutations in Zidovudine-Resistant Human Immunodeficiency Virus

1991 • 70 citations

Polymerase chain reaction identification of Bordetella pertussis infections in vaccinees and family members in a pertussis vaccine efficacy trial in Germany

1995 • 70 citations

Identification of Bordetella pertussis in nasopharyngeal swabs by PCR amplification of a region of the adenylate cyclase gene

1993 • 69 citations

The bacterial DNA content of mouse organs in the Cornell model of dormant tuberculosis

1995 • 69 citations

Routine application of the polymerase chain reaction for detection of Mycobacterium tuberculosis in clinical samples.

1995 • 68 citations

Prospective application of reverse transcriptase polymerase chain reaction for diagnosing influenza infections in respiratory samples from a children's hospital

1993 • 66 citations

Specific amplification of Aspergillus fumigatus DNA by polymerase chain reaction

1993 • 66 citations

Rapid diagnosis of Mycobacterium tuberculosis bacteremia by PCR

1996 • 66 citations

Quantitation of Plasma Human Immunodeficiency Virus Type 1 RNA by Competitive Polymerase Chain Reaction

1992 • 65 citations

Use of PCR in routine diagnosis of treated and untreated pulmonary tuberculosis.

1993 • 64 citations

Comparison of nasopharyngeal aspirates and throat swab specimens in a polymerase chain reaction-based test forMycoplasma pneumoniae

1995 • 64 citations

Genetic diversity and identification of human infection by amplification of the chlamydial 60-kilodalton cysteine-rich outer membrane protein gene

1991 • 64 citations

Diagnosis of Chlamydia pneumoniae Infection in Patients with Community-Acquired Pneumonia by Polymerase Chain Reaction Enzyme Immunoassay

1994 • 63 citations

Detection of human rhinovirus RNA in nasal washings by PCR

1993 • 63 citations

Use of Polymerase Chain Reaction in an Epidemiologic Investigation of Pontiac Fever

1993 • 62 citations

Inactivation of polymerase inhibitors for Mycobacterium tuberculosis DNA amplification in sputum by using capture resin

1995 • 61 citations

16S rRNA based polymerase chain reaction compared with culture and serological methods for diagnosis ofMycoplasma pneumoniae infection

1994 • 61 citations

Sensitive and specific polymerase chain reaction assays for detection of Bordetella pertussis in nasopharyngeal specimens

1994 • 60 citations

Utility of an internal control for the polymerase chain reaction

1992 • 60 citations

Application of New Technology to the Detection, Identification, and Antimicrobial Susceptibility Testing of Mycobacteria

1994 • 59 citations

Pertussis in Missouri: Evaluation of Nasopharyngeal Culture, Direct Fluorescent Antibody Testing, and Clinical Case Definitions in the Diagnosis of Pertussis

1993 • 57 citations

Mycobacterium smegmatis strain for detection of Mycobacterium tuberculosis by PCR used as internal control for inhibition of amplification and for quantification of bacteria

1994 • 57 citations

Rapid Diagnosis of Mycoplasma pneumoniae Infection: Clinical Evaluation of a Commercial Probe Test

1990 • 56 citations

Quantitative culture of Mycobacterium tuberculosis from clinical sputum specimens and dilution endpoint of its detection by the Amplicor PCR assay

1995 • 55 citations

Rapid detection of Mycoplasma pneumoniae in clinical samples by the polymerase chain reaction

1993 • 52 citations

Development and evaluation of a rapid and simple procedure for detection of Pneumocystis carinii by PCR

1994 • 51 citations

Experience with Newer Techniques for the Laboratory Detection of Mycoplasma pneumoniae Infection: Adelaide, 1978–1992

1993 • 50 citations

Detection ofLegionella DNA in human and guinea pig urine samples by the polymerase chain reaction

1995 • 50 citations

Detection ofChlamydia pneumoniae in clinical specimens by polymerase chain reaction using nested primers

1994 • 48 citations

Diagnosis of Pneumocystis carinii pneumonia: Specificity and sensitivity of polymerase chain reaction in comparison with immunofluorescence in bronchoalveolar lavage specimens

1993 • 47 citations

Structure of two sulphated oligosaccharides from respiratory mucins of a patient suffering from cystic fibrosis. A fast-atom-bombardment m.s. and 1H-n.m.r. spectroscopic study

1991 • 47 citations

Nested PCR optimized for detection of Bordetella pertussis in clinical nasopharyngeal samples

1994 • 44 citations

Comparison of polymerase chain reaction and conventional culture for the detection of legionellas in hospital water samples

1994 • 42 citations

Comparison of sample preparation methods for detection of Chlamydia pneumoniae in bronchoalveolar lavage fluid by PCR

1994 • 42 citations

Use of the polymerase chain reaction to detectBordetella pertussis in patients with mild or atypical symptoms of infection

1993 • 41 citations

Ligation amplification and fluorescence detection of Mycobacterium tuberculosis DNA

1993 • 41 citations

Polymerase chain reaction and sequencing for typing rhinovirus RNA

1994 • 41 citations

Evaluation of mtp40 genomic fragment amplification for specific detection of Mycobacterium tuberculosis in clinical specimens

1996 • 40 citations

Detection of candidemia by polymerase chain reaction

1994 • 40 citations

Ability of PCR assay to identify Mycobacterium tuberculosis in BACTEC 12B vials

1994 • 38 citations

Polymerase chain reaction for detection ofMycobacterium tuberculosis in sputum

1993 • 37 citations

Pulmonary fungal infections in immunocompromised patients: incidence and risk factors

1994 • 36 citations

Quantitative and qualitative comparison of DNA amplification by PCR with immunofluorescence staining for diagnosis of Pneumocystis carinii pneumonia.

1993 • 35 citations

An improved method for the detection of hepatitis C virus RNA in plasma utilizing heminested primers and internal control RNA.

1993 • 34 citations

Typing of Human Rhinoviruses Based on Sequence Variations in the 5' Non-coding Region

1989 • 31 citations

Competitive polymerase chain reaction using an internal standard: Application to the quantitation of viral DNA

1992 • 30 citations

Q-beta replicase-amplified assay for detection of Mycobacterium tuberculosis directly from clinical specimens

1995 • 30 citations

PCR detection and differentiation of Chlamydia pneumoniae, Chlamydia psittaci and Chlamydia trachomatis

1992 • 30 citations

Sputum Digestion

1966 • 30 citations

Amplification of Mycobacterium tuberculosis from peripheral blood

1995 • 28 citations

Evaluation of the detection limits of PCR for identification of Mycoplasma pneumoniae in clinical samples

1994 • 28 citations

Sample preparation for Chlamydia pneumoniae PCR

1995 • 27 citations

Detection of pathogenic fungi in human blood by the polymerase chain reaction

1995 • 27 citations

Comparison of amplified Q beta replicase and PCR assays for detection of Mycobacterium tuberculosis

1995 • 26 citations

Distinguishing Chlamydia species by restriction analysis of the major outer membrane protein gene

1992 • 26 citations

Use of synthetic oligonucleotide probes to detect rhinovirus RNA

1989 • 25 citations

Influence of volume of sample processed on detection of Chlamydia trachomatis in urogenital samples by PCR

1995 • 24 citations

Simple method for production of internal control DNA for Mycobacterium tuberculosis polymerase chain reaction assays

1993 • 22 citations

Modern methods for diagnosis of Mycoplasma pneumoniae pneumonia

1993 • 21 citations

Evaluation of DNA probe test for rapid diagnosis of Mycoplasma pneumoniae infections

1990 • 21 citations

Improved performance of Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test when 500 instead of 50 microliters of decontaminated sediment is used

1996 • 18 citations

Comparison of Pneumocystis carinii detection by toluidine blue O staining, direct immunofluorescence and DNA amplification in sputum specimens from HIV positive patients

1994 • 17 citations

Laboratory diagnosis and occurrence of Pneumocystis carinii.

1994 • 16 citations

Prevalence of Chlamydia pneumoniae in acute lower respiratory infection in the pediatric population in Japan

1994 • 12 citations

Rapid speciation of the five most medically relevant candida species using PCR amplification and a microtiter plate-based detection system

1996 • 12 citations

Polymerase chain reaction amplifying DNA coding for species-specific rRNA of Mycobacterium leprae.

1992 • 12 citations

Comparison of three primer sets for the detection of Mycobacterium tuberculosis in clinical samples by polymerase chain reaction.

1993 • 10 citations

Polymerase chain reaction for detection ofChlamydia pneumoniae in gargled-water specimens of children

1995 • 10 citations

DIAGNOSTIC EFFICACY OF A MYCOPLASMA PNEUMONIAE HYBRIDIZATION TEST IN NASOPHARYNGEAL ASPIRATES OF CHILDREN

1993 • 8 citations

[Detection of Aspergillus fumigatus DNA by polymerase chain reaction in the clinical samples from individuals with pulmonary aspergillosis].

1994 • 7 citations

Evaluation Of The Gen-Probe AmplifiedMycobacterium TuberculosisDirect Test For The Routine Diagnosis Of Pulmonary Tuberculosis

1996 • 7 citations

Techniques and diagnostic applications of in vitro nucleic-acid amplification

1994 • 7 citations

FDA approves rapid test for smear-positive tuberculosis

1996 • 6 citations

Pneumocystis carinii Pneumonia Monitored by P. carinii Shedding in Sputum by the Polymerase Chain Reaction.

1993 • 6 citations

Rapid Diagnosis of Viral Respiratory Infections. Comparison Between Immunofluorescence on Clinical Samples and Immunofluorescence on Centrifuged Cell Cultures

1991 • 4 citations

Comparison of a chemiluminometric immunoassay with culture for diagnosis of chlamydial infections in infants

1992 • 4 citations

Le Programme régional de vaccination en Europe (1991-1993)

1994 • 3 citations

[The regional vaccination program in Europe (1991-1993)].

1994 • 1 citations

Deleted Work

1955 • 0 citations