Structure of two sulphated oligosaccharides from respiratory mucins of a patient suffering from cystic fibrosis. A fast-atom-bombardment m.s. and 1H-n.m.r. spectroscopic study

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

2013 • 2,504 citations

The Immotile-Cilia Syndrome

1977 • 635 citations

P‐glycoprotein: multidrug‐resistance and a superfamily of membrane‐associated transport proteins

1989 • 512 citations

Increased sulfation of glycoconjugates by cultured nasal epithelial cells from patients with cystic fibrosis.

1989 • 216 citations

Isolation and structural characterization of low‐molecular‐mass monosialyl oligosaccharides derived from respiratory‐mucus glycoproteins of a patient suffering from bronchiectasis

1988 • 121 citations

Primary structure determination of five sialylated oligosaccharides derived from bronchial mucus glycoproteins of patients suffering from cystic fibrosis. The occurrence of the NeuAc alpha(2----3)Gal beta(1----4)[Fuc alpha(1----3)] GlcNAc beta(1----.) structural element revealed by 500-MHz 1H NMR spectroscopy.

1984 • 106 citations

Complex structure of human bronchial mucus glycoprotein

1984 • 90 citations

Primary structure of neutral oligosaccharides derived from respiratory‐mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500‐MHz ¹H‐NMR spectroscopy and quantitative sugar analysis

1988 • 88 citations

Structures of O‐glycosidically linked oligosaccharides isolated from human meconium glycoproteins

1989 • 83 citations

Occurrence of sulfate in the asparagine-linked complex carbohydrate units of thyroglobulin. Identification and localization of galactose 3-sulfate and N-acetylglucosamine 6-sulfate residues in the human and calf proteins.

1988 • 80 citations

Structure of sialyl-oligosaccharides isolated from bronchial mucus glycoproteins of patients (blood group O) suffering from cystic fibrosis

1987 • 77 citations

Structure determination of five sulfated oligosaccharides derived from tracheobronchial mucus glycoproteins.

1987 • 72 citations

Further characterization, by a combined high-performance liquid chromatography/1H-NMR approach, of the heterogeneity displayed by the neutral carbohydrate chains of human bronchial mucins

1984 • 68 citations

Abnormal Respiratory Epithelial Ion Transport in Cystic Fibrosis

1986 • 67 citations

Isolation and Characterization of Oligosaccharides from Canine Submaxillary Mucin

1974 • 62 citations

Enzymatic sulfation of mucus glycoprotein in gastric mucosa. Effect of ethanol.

1988 • 61 citations

Chemical and physical properties of human bronchial mucus glycoproteins

1979 • 53 citations

Characterization of a Thyroid Sulfotransferase Responsible for the 3-O-Sulfation of Terminal β-D-Galactosyl Residues in N-Linked Carbohydrate Units

1989 • 39 citations

Defective epithelial ion transport in cystic fibrosis.

1989 • 37 citations

Complete 1H- and 13C-n.m.r. assignments for two sulphated oligosaccharide alditols of hen ovomucin

1989 • 34 citations

Incorporation in vitro of [3H]glucosamine or [3H]glucose and [35S]SO42- into rat gastric mucosa. Presence of N-acetylhexosamine mono- and disulfates and galactose monosulfate in glycoprotein.

1982 • 33 citations

Mucins from cystic fibrosis sputum.

1976 • 32 citations

Tracheobronchial mucus secretion in vivo and in vitro by epithelial tissues from cystic fibrosis and control subjects.

1976 • 30 citations

Heterogeneite des chaines glycanniques des mucines bronchiques acides isolees a partir de l'expectoration de deux sujets atteints de bronchite chronique

1977 • 23 citations

Increased sulfate uptake in skin fibroblasts isolated from cystic fibrosis patients

1988 • 21 citations

Characterization of sulphated monosaccharides from stumptail monkey (Macaca arctoides) salivary mucin

1981 • 14 citations

Isolation, chemical and biological characterization of sulphated glycoproteins synthesized by rat buccal and palatal minor salivary glands in vivo and in vitro

1987 • 14 citations

[Isolation, physico-chemical properties and composition of pig alpha 2-macroglobulin].

1965 • 7 citations