In VivoExpression and Regulation of Elk-1, a Target of the Extracellular-Regulated Kinase Signaling Pathway, in the Adult Rat Brain

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

AChE-stained horizontal sections of the rat brain in stereotaxic coordinates

1980 • 4,422 citations

The MAPK signaling cascade

1995 • 3,300 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

Calcium Signaling in Neurons: Molecular Mechanisms and Cellular Consequences

1995 • 1,421 citations

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

1995 • 1,367 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1993 • 1,313 citations

MKK3- and MKK6-Regulated Gene Expression Is Mediated by the p38 Mitogen-Activated Protein Kinase Signal Transduction Pathway

1996 • 1,286 citations

Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

1996 • 1,253 citations

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways

1993 • 1,165 citations

Nuclear localization and regulation of erk- and rsk-encoded protein kinases.

1992 • 1,107 citations

The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones

1990 • 1,021 citations

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

1988 • 983 citations

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

1992 • 980 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

The Ets family of transcription factors

1993 • 848 citations

Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism

1996 • 781 citations

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

1997 • 724 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.

1995 • 667 citations

Activation of p42 Mitogen-activated Protein Kinase in Hippocampal Long Term Potentiation

1996 • 575 citations

MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia

1997 • 548 citations

Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

1995 • 535 citations

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

1989 • 495 citations

Stimulation of Protein Tyrosine Phosphorylation by NMDA Receptor Activation

1991 • 464 citations

The serum response element

1992 • 458 citations

Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF

1991 • 447 citations

Functional analysis of a growth factor-responsive transcription factor complex

1993 • 386 citations

Journey to the surface of the cell: Fos regulation and the SRE.

1995 • 376 citations

Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements

1995 • 300 citations

Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun.

1994 • 296 citations

The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion

1994 • 266 citations

elk , Tissue-Specific ets -Related Genes on Chromosomes X and 14 Near Translocation Breakpoints

1989 • 261 citations

Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET).

1995 • 255 citations

Nuclear Localization and Regulation of erk-and rsk-Encoded Protein Kinases

1992 • 246 citations

Protein Synthesis Inhibitors Reveal Differential Regulation of Mitogen-Activated Protein Kinase and Stress-Activated Protein Kinase Pathways That Converge on Elk-1

1995 • 243 citations

Postsynaptic NMDA receptor-mediated calcium accumulation in hippocampal CAl pyramidal cell dendrites

1990 • 234 citations

Net, a new ets transcription factor that is activated by Ras.

1994 • 216 citations

Calcium Activates Serum Response Factor-Dependent Transcription By A Ras- and Elk-1-Independent Mechanism That Involves a Ca²⁺/Calmodulin-Dependent Kinase

1995 • 215 citations

Extracellular signal-regulated protein kinases (ERKs) and ERK kinase (MEK) in brain: regional distribution and regulation by chronic morphine

1995 • 212 citations

Calcium Regulation of Gene Expression: Isn't That Spatial?

1997 • 206 citations

JUN, FOS, KROX, and CREB transcription factor proteins in the rat cortex: Basal expression and induction by spreading depression and epileptic seizures

1993 • 174 citations

p42 mitogen-activated protein kinase in brain: Prominent localization in neuronal cell bodies and dendrites

1993 • 158 citations

Synergism in ternary complex formation between the dimeric glycoprotein p67SRF, polypeptide p62TCF and the c-fos serum response element.

1990 • 157 citations

Activation of Mitogen‐Activated Protein Kinase in Cultured Rat Hippocampal Neurons by Stimulation of Glutamate Receptors

1995 • 155 citations

c-fos transcriptional activation and repression correlate temporally with the phosphorylation status of TCF.

1993 • 153 citations

Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo.

1994 • 144 citations

Activation of p42 Mitogen‐Activated Protein Kinase by Glutamate Receptor Stimulation in Rat Primary Cortical Cultures

1993 • 141 citations

Differential Regulation of Proline-rich Tyrosine Kinase 2/Cell Adhesion Kinase β (PYK2/CAKβ) and pp125FAK by Glutamate and Depolarization in Rat Hippocampus

1996 • 135 citations

ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development.

1994 • 121 citations

Ras/MAP kinase-dependent and -independent signaling pathways target distinct ternary complex factors.

1994 • 113 citations

Effect of electrical stimulation of the cerebral cortex on the expression of the fos protein in the basal ganglia

1997 • 112 citations

Trans-synaptic regulation of gene expression

1992 • 104 citations

Functional dissection of the transcription factor Elk-1.

1994 • 90 citations

Retrograde axonal transport of signal transduction proteins in rat sciatic nerve

1995 • 88 citations

Anisomycin-Activated Protein Kinases p45 and p55 but Not Mitogen-Activated Protein Kinases ERK-1 and -2 Are Implicated in the Induction of c-fos and c-jun

1994 • 60 citations

The regional distribution of extracellularly regulated kinase-1 and -2 messenger RNA in the adult rat central nervous system

1993 • 54 citations

Stress activated protein kinases, a novel family of mitogen-activated protein kinases, are heterogeneously expressed in the adult rat brain and differentially distributed from extracellular-signal-regulated protein kinases

1995 • 47 citations

Transient Activation of RAF-1, MEK, and ERK2 Coincides Kinetically with Ternary Complex Factor Phosphorylation and Immediate-Early Gene Promoter Activity In Vivo

1994 • 41 citations

ERP, a New Member of the ets Transcription Factor/Oncoprotein Family: Cloning, Characterization, and Differential Expression during B-Lymphocyte Development

1994 • 37 citations

Presence of a Cyclic AMP Response Element‐Binding Protein in Oligodendrocytes

1993 • 27 citations

Heterogeneity of ternary complex factors in HeLa cell nuclear extracts.

1994 • 17 citations