Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Applied Regression Analysis and Other Multivariable Methods

1989 • 8,685 citations

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

1984 • 1,477 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

1985 • 927 citations

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells.

1986 • 688 citations

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1986 • 680 citations

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

A rapid method for the isolation of L-cell surface membranes using an aqueous two-phase polymer system

1971 • 448 citations

Genetic and biochemical characterization of multidrug resistance

1985 • 405 citations

Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers.

1983 • 384 citations

Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability.

1979 • 368 citations

Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin.

1987 • 343 citations

Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen.

1981 • 275 citations

Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells.

1986 • 255 citations

Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.

1987 • 180 citations

Drug resistance in cancer.

1984 • 175 citations

Detection and mapping of homologous, repeated and amplified DNA sequences by DNA renaturation in agarose gets

1983 • 135 citations

Comparison of Antineoplastic Activity of Aminoethylaminoanthraquinones and Anthracycline Antibiotics

1979 • 101 citations

Comparative molecular pharmacology in leukemic L1210 cells of the anthracene anticancer drugs mitoxantrone and bisantrene.

1985 • 73 citations

Evidence for the metabolism of mitozantrone by microsomal glutathione transferases and 3-methylcholanthrene-inducible glucuronosyl transferases

1986 • 70 citations

Mitoxantrone: A phase II study in the treatment of patients with advanced breast carcinoma and other solid tumours

1982 • 56 citations

[20] Methods for chromosome banding of human and experimental tumors in Vitro

1987 • 55 citations

Membrane Mutants of Mammalian Cells in Culture

1978 • 42 citations

A method for the simultaneous measurement of the new anthracycline derivative 4′ -deoxydoxorubicin and its metabolites by reversed phase liquid chromatography

1984 • 13 citations