Infiltration of forkhead box P3-expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 • 7,470 citations

An essential role for Scurfin in CD4+CD25+ T regulatory cells

2003 • 2,825 citations

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2005 • 2,667 citations

Revised criteria for diagnosis of coeliac disease. Report of Working Group of European Society of Paediatric Gastroenterology and Nutrition.

1990 • 1,291 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

Transient expression of FOXP3 in human activated nonregulatory CD4⁺ T cells

2006 • 973 citations

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3

2005 • 957 citations

Coordinated Induction by IL15 of a TCR-Independent NKG2D Signaling Pathway Converts CTL into Lymphokine-Activated Killer Cells in Celiac Disease

2004 • 809 citations

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

2006 • 773 citations

A Direct Role for NKG2D/MICA Interaction in Villous Atrophy during Celiac Disease

2004 • 724 citations

Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease

2003 • 605 citations

Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease

1998 • 460 citations

Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease

2003 • 449 citations

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

2004 • 415 citations

Induction of T helper type 1–like regulatory cells that express Foxp3 and protect against airway hyper-reactivity

2004 • 313 citations

Interleukin 15 mediates epithelial changes in celiac disease

2000 • 260 citations

Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease

2002 • 179 citations

Immunologic Activity in the Small Intestinal Mucosa of Pediatric Patients With Type 1 Diabetes

2003 • 168 citations

Screening for coeliac disease in type 1 diabetes

2002 • 165 citations

Diagnosis of coeliac disease

2005 • 158 citations

Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease

2002 • 153 citations

Pathomechanisms in celiac disease

2005 • 152 citations

Activated T lymphocytes in the celiac lesion: Non‐proliferative activation (CD25) of CD4⁺ α/β cells in the lamina propria but proliferation (Ki‐67) of α/β and γ/δ cells in the epithelium

1993 • 141 citations

Interleukin-18 Promoter Polymorphisms in Type 1 Diabetes

2002 • 137 citations

Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa

2004 • 136 citations

Gliadin-Specific Type 1 Regulatory T Cells from the Intestinal Mucosa of Treated Celiac Patients Inhibit Pathogenic T Cells

2006 • 135 citations

Intestinal γ/δ Receptor-Bearing T Lymphocytes in Celiac Disease and Inflammatory Bowel Diseases in Children. Constant Increase in Celiac Disease

1990 • 130 citations

Intraepithelial γδ T-cell-receptor lymphocytes and genetic susceptibility to coeliac disease

1992 • 127 citations

A Sudden Decline in Active Membrane-Bound TGF-β Impairs Both T Regulatory Cell Function and Protection against Autoimmune Diabetes

2004 • 104 citations

Raised pro-inflammatory cytokines interleukin 6 and tumour necrosis factor alpha in coeliac disease mucosa detected by immunohistochemistry.

1994 • 99 citations

Gluten Stimulation of Coeliac Mucosa In Vitro Induces Activation (CD25) of Lamina Propria CD4^H T cells and Macrophages but no Crypt‐Cell Hyperplasia

1993 • 90 citations

Serum levels of the interferon-γ-inducing cytokine interleukin-18 are increased in individuals at high risk of developing Type I diabetes

2001 • 90 citations

In Vitro–Deranged Intestinal Immune Response to Gliadin in Type 1 Diabetes

2004 • 90 citations

A Type 1 Diabetes-related Protein from Wheat (Triticum aestivum)

2002 • 88 citations

Virus infection induces proteolytic processing of IL-18 in human macrophages via caspase-1 and caspase-3 activation

2001 • 83 citations

FoxP3+CD4+CD25+ T cells with regulatory properties can be cultured from colonic mucosa of patients with Crohn's disease

2005 • 83 citations

Detection of interferon gamma mRNA in the mucosa of patients with coeliac disease by in situ hybridisation.

1994 • 71 citations

Inflammatory cytokines in small intestinal mucosa of patients with potential coeliac disease

2002 • 66 citations

T‐Cell Reactivity to Wheat Gluten in Patients with Insulin‐Dependent Diabetes Mellitus

1998 • 58 citations

Interleukin 18 maintains a long-standing inflammation in coeliac disease patients

2006 • 52 citations

Immunohistochemical changes in the jejunum in first degree relatives of patients with coeliac disease and the coeliac disease marker DQ genes. HLA class II antigen expression, interleukin-2 receptor positive cells and dividing crypt cells.

1994 • 40 citations

Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.

2000 • 36 citations