Activation of the human T-cell leukemia virus type I long terminal repeat by 12-O-tetradecanoylphorbol-13-acetate and by tax (p40x) occurs through similar but functionally distinct target sequences

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA.

1983 • 1,555 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor

1988 • 607 citations

The tat Gene of Human T-Lymphotropic Virus Type 1 Induces Mesenchymal Tumors in Transgenic Mice

1987 • 522 citations

Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.

1986 • 519 citations

fos-associated cellular p39 is related to nuclear transcription factor AP-1

1988 • 508 citations

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex

1988 • 488 citations

HTLV-I Tax Induces Cellular Proteins that Activate the κB Element in the IL-2 Receptor α Gene

1988 • 480 citations

Activation of the HIV-1 LTR by T Cell Mitogens and the Trans-Activator Protein of HTLV-I

1987 • 460 citations

Regulation of the human interleukin-2 receptor α chain promoter: Activation of a nonfunctional promoter by the transactivator gene of HTLV-I

1987 • 423 citations

Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

1987 • 379 citations

Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus

1984 • 341 citations

Cellular Transcription Factors and Regulation of IL-2 Receptor Gene Expression by HTLV-I tax Gene Product

1988 • 327 citations

Human immunodeficiency virus long terminal repeat responds to T-cell activation signals.

1987 • 292 citations

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

1988 • 259 citations

Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat

1987 • 251 citations

Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

1987 • 236 citations

Involvement of common and cell type-specific pathways in c-fos gene control: Stable induction by cAMP in macrophages

1987 • 223 citations

Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence

1988 • 218 citations

Requirement of multiple copies of a 21-nucleotide sequence in the U3 regions of human T-cell leukemia virus type I and type II long terminal repeats for trans-acting activation of transcription.

1986 • 212 citations

Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins.

1988 • 198 citations

Antigens Encoded by the 3′-Terminal Region of Human T-Cell Leukemia Virus: Evidence for a Functional Gene

1984 • 191 citations

Human adult T-cell leukemia virus: molecular cloning of the provirus DNA and the unique terminal structure.

1982 • 188 citations

Transcription Control by Oncogenes

1985 • 176 citations

Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer.

1986 • 175 citations

HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene

1988 • 171 citations

Phorbol ester enhances human immunodeficiency virus-promoted gene expression and acts on a repeated 10-base-pair functional enhancer element.

1987 • 164 citations

Phorbol ester induces the transcriptional stimulatory activity of the SV40 enhancer

1986 • 146 citations

Tumor promoter, TPA, enhances replication of HTLV-III/LAV

1986 • 133 citations

Regulation of HIV and HTLV gene expression.

1988 • 128 citations

Binding of host-cell factors to DNA sequences in the long terminal repeat of human T-cell leukemia virus type I: implications for viral gene expression.

1988 • 107 citations

Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript

1983 • 104 citations

Molecular mechanisms of phorbol ester, thyrotropin-releasing hormone, and growth factor stimulation of prolactin gene transcription.

1985 • 98 citations

Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type 1 or the human T-cell leukemia virus type I tat proteins occurs in the absence of de novo protein synthesis.

1988 • 77 citations

Repetitive structure in the long-terminal-repeat element of a type II human T-cell leukemia virus.

1984 • 71 citations

Abundant synthesis of functional human T-cell leukemia virus type I p40x protein in eucaryotic cells by using a baculovirus expression vector

1987 • 66 citations

Long terminal repeat structure of an american isolate of type I human T-cell leukemia virus

1984 • 63 citations

Human T-cell leukemia virus types I and II exhibit different DNase I protection patterns

1988 • 57 citations

Expression of the complete human T-cell leukemia virus type I pX coding sequence as a functional protein in Escherichia coli.

1986 • 39 citations

Phorbol ester and Epstein—Barr virus dependent transformation of normal primary human skin epithelial cells

1987 • 37 citations

Transient expression of foreign genes in lymphoid cells is enhanced by phorbol ester.

1987 • 15 citations

Transient Expression of Foreign Genes in Lymphoid Cells is Enhanced by Phorbol Ester

1987 • 9 citations