The Androgen Receptor: An Overview

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

1987 • 1,920 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

1991 • 1,501 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

1984 • 1,416 citations

Sequence and Expression of Human Estrogen Receptor Complementary DNA

1986 • 1,321 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism

1974 • 1,241 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Cloning of Human Androgen Receptor Complementary DNA and Localization to the X Chromosome

1988 • 1,007 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

A mutation in the ligand binding domain of the androgen receptor of human INCaP cells affects steroid binding characteristics and response to anti-androgens

1990 • 948 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

1988 • 908 citations

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

1988 • 705 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

Familial Incomplete Male Pseudohermaphroditism, Type 2

1974 • 617 citations

Transcriptional activation and nuclear targeting signals of the human androgen receptor.

1991 • 611 citations

Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

1988 • 600 citations

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.

1987 • 597 citations

The syndrome of testicular feminization in male pseudohermaphrodites

1953 • 596 citations

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1988 • 588 citations

Activators and targets

1990 • 582 citations

The Human Androgen Receptor: Complementary Deoxyribonucleic Acid Cloning, Sequence Analysis and Gene Expression in Prostate

1988 • 575 citations

X-linked Gene for Testicular Feminization in the Mouse

1970 • 551 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

Many Transcription Factors Interact Synergistically with Steroid Receptors

1988 • 517 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

Immunohistochemical Localization of the Androgen Receptor in Rat and Human Tissues*

1990 • 492 citations

Characterization and expression of a cDNA encoding the human androgen receptor.

1989 • 483 citations

Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones.

1992 • 430 citations

Testosterone at High Concentrations Interacts with the Human Androgen Receptor Similarly to Dihydrotestosterone*

1990 • 428 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor

1988 • 427 citations

Androgen receptor gene mutations in human prostate cancer.

1992 • 421 citations

Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA

1987 • 419 citations

Synergistic action of the glucocorticoid receptor with transcription factors.

1988 • 407 citations

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

1992 • 381 citations

Regulation of Progesterone Receptor-Mediated Transcription by Phosphorylation

1990 • 365 citations

Transcriptional regulation by dimerization: Two sides to an incestuous relationship

1990 • 343 citations

Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.

1990 • 333 citations

Mechanisms of nuclear localization of the progesterone receptor: Evidence for interaction between monomers

1989 • 329 citations

Binding properties of androgen receptors. Evidence for identical receptors in rat testis, epididymis, and prostate.

1976 • 310 citations

Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism.

1989 • 301 citations

Anatomy of the Steroid Receptor Zinc Finger Region

1992 • 299 citations

The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific

1989 • 299 citations

Nucleocytoplasmic shuttling of the progesterone receptor.

1991 • 296 citations

A Domain Containing Leucine-Zipper-Like Motifs Mediate Novelin VivoInteractions between the Thyroid Hormone and Retinoic Acid Receptors

1989 • 293 citations

Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation

1992 • 284 citations

The Rat Androgen Receptor: Primary Structure, Autoregulation of its Messenger Ribonucleic Acid, and Immunocytochemical Localization of the Receptor Protein

1988 • 277 citations

Autologous Down-Regulation of Androgen Receptor Messenger Ribonucleic Acid

1990 • 272 citations

Aspects of Androgen-Dependent Events as Studied by Antiandrogens

1970 • 270 citations

Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors.

1990 • 257 citations

The chicken progesterone receptor: sequence, expression and functional analysis.

1987 • 236 citations

Negative controls of cell proliferation: human prostate cancer cells and androgens.

1989 • 233 citations

Steroid requirement for androgen receptor dimerization and DNA binding. Modulation by intramolecular interactions between the NH2-terminal and steroid-binding domains.

1993 • 215 citations

Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor

1990 • 211 citations

Identification of phosphorylated sites in the mouse glucocorticoid receptor.

1991 • 208 citations

Aberrant response in vitro of hormone‐responsive prostate cancer cells to antiandrogens

1989 • 208 citations

Intracellular Localization of the Glucocorticoid Receptor: Evidence for Cytoplasmic and Nuclear Localization*

1987 • 197 citations

Locus on human X chromosome for dihydrotestosterone receptor and androgen insensitivity.

1975 • 182 citations

Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: High affinity for progestagenic and estrogenic steroids

1990 • 165 citations

Vitamin D receptor interaction with specific DNA. Association as a 1,25-dihydroxyvitamin D3-modulated heterodimer.

1991 • 156 citations

Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization

1972 • 156 citations

The Purified Activated Glucocorticoid Receptor is a Homodimer

1989 • 156 citations

Protein Phosphatase Types 1 and/or 2A Regulate Nucleocytoplasmic Shuttling of Glucocorticoid Receptors

1991 • 153 citations

Functional Domains of the Human Vitamin D₃Receptor Regulate Osteocalcin Gene Expression

1989 • 139 citations

Hormonal regulation and identification of chicken progesterone receptor phosphorylation sites.

1990 • 131 citations

Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein

1988 • 129 citations

Agonist-dependent phosphorylation and nuclear dephosphorylation of glucocorticoid receptors in intact cells

1989 • 126 citations

Effects of proteases and protease inhibitors on the 4.5 S and 8 S androgen receptor.

1979 • 125 citations

Phosphorylation on Tyrosine ofin VitroSynthesized Human Estrogen Receptor Activates Its Hormone Binding

1989 • 122 citations

Response elements of the androgen-regulated C3 gene.

1992 • 119 citations

Hormone-dependent phosphorylation of the glucocorticoid receptor occurs mainly in the amino-terminal transactivation domain.

1990 • 112 citations

A 55-Kilodalton Accessory Factor Facilitates Vitamin D Receptor DNA Binding

1991 • 109 citations

In Vitro Transcription Enhancement by Purified Derivatives of the Glucocorticoid Receptor

1989 • 107 citations

Characterization and Functional Properties of the A and B Forms of Human Progesterone Receptors Synthesized in a Baculovirus System

1991 • 105 citations

Phosphotryptic Peptide Analysis of Human Progesterone Receptors

1989 • 95 citations

Overexpression and characterization of the human mineralocorticoid receptor.

1991 • 95 citations

Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro.

1990 • 78 citations

Efficient, low-cost protein factories: expression of human adenosine deaminase in baculovirus-infected insect larvae.

1990 • 73 citations

Expression of Recombinant Androgen Receptor in Cultured Mammalian Cells

1990 • 72 citations

Zinc potentiation of androgen receptor binding to nuclei in vitro

1984 • 61 citations

Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system

1991 • 58 citations

Overexpression of Full-Length Human Glucocorticoid Receptor inSpodoptera frugiperdaCells Using the Baculovirus Expression Vector System

1990 • 58 citations

Identification of an 8S Androgen Receptor-Promoting Factor that Converts the 4.5S Form of the Androgen Receptor to 8S*

1981 • 52 citations

Structure and function of the androgen receptor

1989 • 49 citations

Progestins can mimic, inhibit and potentiate the actions of androgens

1983 • 47 citations

Expression of androgen receptor in insect cells. Purification of the receptor and renaturation of its steroid- and DNA-binding functions.

1992 • 46 citations

Immunocytochemical localization of progesterone receptors in breast cancer with anti-human receptor monoclonal antibodies.

1988 • 45 citations

Dimerization of the Chicken Progesterone Receptorin VitroCan Occur in the Absence of Hormone and DNA

1990 • 44 citations

Characterization of human androgen receptor overexpressed in the baculovirus system.

1992 • 39 citations

The possible role of disulfide bond reduction in transformation of the 10 S androgen receptor.

1986 • 36 citations

Interconversion of androgen receptor forms by divalent cations and 8 S androgen receptor-promoting factor. Effects of Zn2+, Cd2+, Ca2+, and Mg2+.

1985 • 36 citations

Intracellular Localization and Translocation of 1.ALPHA.,25-Dihydroxyvitamin D3 Receptor in Osteoblasts.

1992 • 35 citations

Phosphorylation of transfected wild type and mutated progesterone receptors.

1991 • 32 citations

Overexpression of a Partial Human Androgen Receptor inE. coli: Characterization of Steroid Binding, DNA Binding, and Immunological Properties

1990 • 29 citations

Androgen receptor binding to nuclear matrix in vitro and its inhibition by 8S androgen receptor promoting factor

1984 • 22 citations