Functional Domains of the Human Vitamin D₃Receptor Regulate Osteocalcin Gene Expression

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.

1981 • 1,025 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

1,25-Dihydroxyvitamin D ₃ : a Novel Immunoregulatory Hormone

1984 • 536 citations

Molecular Cloning of Complementary DNA Encoding the Avian Receptor for Vitamin D

1987 • 516 citations

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

1987 • 512 citations

1 alpha,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells.

1984 • 493 citations

Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscle.

1985 • 483 citations

New procedure for DNA transfection with polycation and dimethyl sulfoxide.

1984 • 481 citations

Regulation of Terminal Differentiation of Cultured Mouse Epidermal Cells by lα,25-Dihydroxyvitamin D₃*

1983 • 468 citations

VITAMIN D: RECENT ADVANCES

1983 • 437 citations

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1987 • 428 citations

Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3.

1983 • 424 citations

Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.

1986 • 398 citations

Vitamin D Receptors: Nature and Function

1986 • 362 citations

The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator

1988 • 362 citations

Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein

1988 • 325 citations

Glucocorticoid Receptor Mutants That Define a Small Region Sufficient for Enhancer Activation

1987 • 260 citations

Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain

1988 • 238 citations

Regulation of the hydroxylation of 25-hydroxyvitamin D3 in vivo and in primary cultures of chick kidney cells.

1979 • 213 citations

A Single Domain of the Estrogen Receptor Confers Deoxyribonucleic Acid Binding and Transcriptional Activation of the Rat Prolactin Gene

1988 • 173 citations

Molecular Biology of the Vitamin D Hormone

1988 • 167 citations

1,25-Dihydroxyvitamin D₃Receptors and Hormonal Responses in Cloned Human Skeletal Muscle Cells*

1986 • 163 citations

Influence of 1,25-dihydroxyvitamin D3 on cultured osteogenic sarcoma cells: correlation with the 1,25-dihydroxyvitamin D3 receptor.

1984 • 144 citations

Hormone-dependent phosphorylation of the 1,25-dihydroxyvitamin D3 receptor in mouse fibroblasts

1985 • 142 citations

Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA.

1988 • 133 citations

Purification of chicken intestinal receptor for 1,25-dihydroxyvitamin D.

1979 • 105 citations

Intracellular Receptors Mediate the Biologic Action of 1,25-Dihydroxyvitamin D3

2009 • 68 citations

Association of 1,25-dihydroxyvitamin D3 with cultured 3T6 mouse fibroblasts. Cellular uptake and receptor-mediated migration to the nucleus.

1983 • 64 citations

Chicken intestinal receptor for 1,25-dihydroxyvitamin D3. Immunologic characterization and homogeneous isolation of a 60,000-dalton protein.

1987 • 59 citations

1,25-Dihydroxyvitamin D3 induces 25-hydroxyvitamin D3-24-hydroxylase in a cultured monkey kidney cell line (LLC-MK2) apparently deficient in the high affinity receptor for the hormone.

1984 • 57 citations

Expression of an immunoglobulin heavy chain gene transfected into lymphocytes.

1984 • 53 citations

Immunochemical detection of unique proteolytic fragments of the chick 1,25-dihydroxyvitamin D3 receptor. Distinct 20-kDa DNA-binding and 45-kDa hormone-binding species.

1987 • 48 citations

Trypsin cleavage of chick 1,25-dihydroxyvitamin D3 receptors. Generation of discrete polypeptides which retain hormone but are unreactive to DNA and monoclonal antibody.

1985 • 42 citations

Biosynthesis, purification and receptor binding properties of high specific radioactivity 1α,24(R),25-trihydroxy-[26,27-methyl-3H]-vitamin D3

1982 • 7 citations

CHARACTERIZATION OF THE CHROMOSOMAL GENE OF THE MOUSE VITAMIN D RECEPTOR

1988 • 1 citations