Chemotaxis and Calcium Responses of Phagocytes to Formyl Peptide Receptor Ligands Is Differentially Regulated by Cyclic ADP Ribose

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

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The Molecular Biology of Leukocyte Chemoattractant Receptors

1994 • 1,224 citations

N-formylmethionyl peptides as chemoattractants for leucocytes.

1975 • 871 citations

Formation and Hydrolysis of Cyclic ADP-Ribose Catalyzed by Lymphocyte Antigen CD38

1993 • 735 citations

Formyl-peptide receptors revisited

2002 • 604 citations

Purification and identification of formyl-methionyl-leucyl-phenylalanine as the major peptide neutrophil chemotactic factor produced by Escherichia coli.

1984 • 520 citations

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

2001 • 448 citations

A Calcium-Dependent Feedback Mechanism Participates in Shaping Single NMDA Miniature EPSCs

2001 • 446 citations

Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor.

1994 • 431 citations

Physiological Functions of Cyclic ADP-Ribose and NAADP as Calcium Messengers

2001 • 426 citations

A Seven-transmembrane, G Protein–coupled Receptor, FPRL1, Mediates the Chemotactic Activity of Serum Amyloid A for Human Phagocytic Cells

1999 • 425 citations

Serum amyloid A induces IL-8 secretion through a G protein–coupled receptor, FPRL1/LXA4R

2003 • 319 citations

A Novel Ligand of the Formyl Peptide Receptor

2000 • 317 citations

Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils.

1982 • 309 citations

Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose

1999 • 308 citations

Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis

2001 • 285 citations

Amyloid β₄₂Activates a G-Protein-Coupled Chemoattractant Receptor, FPR-Like-1

2001 • 271 citations

The Isolation and Partial Characterization of Neutrophil Chemotactic Factors from Escherichia Coli

1975 • 268 citations

Impaired Antibacterial Host Defense in Mice Lacking the N-formylpeptide Receptor

1999 • 264 citations

Potentiation of calcium- and caffeine-induced calcium release by cyclic ADP-ribose.

1993 • 259 citations

Enzymatic synthesis and characterizations of cyclic GDP-ribose. A procedure for distinguishing enzymes with ADP-ribosyl cyclase activity.

1994 • 244 citations

Mice Deficient for the Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase CD38 Exhibit Altered Humoral Immune Responses

1998 • 207 citations

A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family.

1992 • 207 citations

Pleiotropic roles of formyl peptide receptors

2001 • 190 citations

Utilization of Two Seven-Transmembrane, G Protein-Coupled Receptors, Formyl Peptide Receptor-Like 1 and Formyl Peptide Receptor, by the Synthetic Hexapeptide WKYMVm for Human Phagocyte Activation

1999 • 184 citations

The signal transduction pathway involved in the migration induced by a monocyte chemotactic cytokine.

1991 • 176 citations

Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor

1992 • 168 citations

CD38‐cyclic ADP‐ribose‐mediated Ca²⁺signaling contributes to airway smooth muscle hyperresponsiveness

2003 • 167 citations

Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast

1998 • 155 citations

Amyloid-β Induces Chemotaxis and Oxidant Stress by Acting at Formylpeptide Receptor 2, a G Protein-coupled Receptor Expressed in Phagocytes and Brain

2001 • 153 citations

β Amyloid peptide (Aβ₄₂) is internalized via the G‐protein‐coupled receptor FPRL1 and forms fibrillar aggregates in macrophages¹

2001 • 138 citations

CD38: a new paradigm in lymphocyte activation and signal transduction

1998 • 137 citations

Cutting Edge: The Neurotoxic Prion Peptide Fragment PrP106–126 Is a Chemotactic Agonist for the G Protein-Coupled Receptor Formyl Peptide Receptor-Like 1

2001 • 136 citations

Differential Expansion of the N-Formylpeptide Receptor Gene Cluster in Human and Mouse

1998 • 130 citations

Species and subtype variants of the N-formyl peptide chemotactic receptor reveal multiple important functional domains.

1993 • 124 citations

Receptor-activated calcium influx in human monocytes exposed to monocyte chemotactic protein-1 and related cytokines.

1993 • 116 citations

Bacterial Lipopolysaccharide Selectively Up-Regulates the Function of the Chemotactic Peptide Receptor Formyl Peptide Receptor 2 in Murine Microglial Cells

2002 • 115 citations

A Synthetic Peptide Derived From Human Immunodeficiency Virus Type 1 gp120 Downregulates the Expression and Function of Chemokine Receptors CCR5 and CXCR4 in Monocytes by Activating the 7-Transmembrane G-Protein–Coupled Receptor FPRL1/LXA4R

1999 • 115 citations

The Conformation of Adenosine Diphosphoribose and 8-Bromoadenosine Diphosphoribose when Bound to Liver Alcohol Dehydrogenase

1975 • 104 citations

N-Formylpeptides Induce Two Distinct Concentration Optima for Mouse Neutrophil Chemotaxis by Differential Interaction with Two N-Formylpeptide Receptor (Fpr) Subtypes

1999 • 103 citations

Formyl Peptide Receptor Signaling in HL-60 Cells through Sphingosine Kinase

1999 • 99 citations

Receptors for chemotactic formyl peptides as pharmacological targets

2002 • 94 citations

Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1

2001 • 91 citations

Intracellular calcium signaling through the CADPR pathway is agonist specific in porcine airway smooth muscle

2003 • 88 citations

Cyclic ADP-Ribose and NAADP: Structures, Metabolism and Functions

2002 • 84 citations

The metamorphosis of a molecule: from soluble enzyme to the leukocyte receptor CD38

1999 • 83 citations

Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP‐ribose

1993 • 81 citations

Potential role of the formyl peptide receptor-like 1 (FPRL1) in inflammatory aspects of Alzheimer's disease

2002 • 80 citations

T20/DP178, an Ectodomain Peptide of Human Immunodeficiency Virus Type 1 gp41, Is an Activator of Human Phagocyte N-Formyl Peptide Receptor

1999 • 74 citations

Characterization of the Signal Transduction Pathway Activated in Human Monocytes and Dendritic Cells by MPIF-1, a Specific Ligand for CC Chemokine Receptor 1

1999 • 68 citations

Innate immunity is regulated by CD38, an ecto-enzyme with ADP-ribosyl cyclase activity

2003 • 68 citations

Receptor-operated Ca2+ influx channels in leukocytes: a therapeutic target?

2002 • 66 citations

Regulation of Ca2+-release-activated Ca2+ current (Icrac) by ryanodine receptors in inositol 1,4,5-trisphosphate-receptor-deficient DT40 cells

2001 • 62 citations

T20/DP178, an Ectodomain Peptide of Human Immunodeficiency Virus Type 1 gp41, Is an Activator of Human Phagocyte N-Formyl Peptide Receptor

1999 • 56 citations

Cyclic ADP-Ribose and NAADP

2002 • 55 citations

cADP-ribose potentiates cytosolic Ca2+ elevation and Ca2+ entry via L-type voltage-activated Ca2+ channels in NG108-15 neuronal cells

2000 • 50 citations

PAF-mediated Ca2+ influx in human neutrophils occurs via store-operated mechanisms

2001 • 49 citations

Down-regulation of the chemokine receptor CCR5 by activation of chemotactic formyl peptide receptor in human monocytes

2000 • 47 citations

Regulation of Ca2+-release-activated Ca2+ current (Icrac) by ryanodine receptors in inositol 1,4,5-trisphosphate-receptor-deficient DT40 cells

2001 • 38 citations

NAD degradation and regulation of CD38 expression by human monocytes/macrophages

2001 • 37 citations

The HIV-1 Cell Entry Inhibitor T-20 Potently Chemoattracts Neutrophils by Specifically Activating the N-Formylpeptide Receptor

2000 • 36 citations

Human CD38, a surface receptor, an enzyme, an adhesion molecule and not a simple marker.

1999 • 36 citations

Control of Ca2+ influx in human neutrophils by inositol 1,4,5-trisphosphate (IP3) binding: differential effects of micro-injected IP3 receptor antagonists

2001 • 27 citations

Verapamil Inhibits Elastase Release and Superoxide Anion Production in Human Neutrophils.

1998 • 27 citations

A Synthetic Peptide Derived From Human Immunodeficiency Virus Type 1 gp120 Downregulates the Expression and Function of Chemokine Receptors CCR5 and CXCR4 in Monocytes by Activating the 7-Transmembrane G-Protein–Coupled Receptor FPRL1/LXA4R

1999 • 15 citations

Pharmacology of Cyclic ADP-Ribose and NAADP

2002 • 15 citations

The N-Formylpeptide Chemotactic Receptor

2020 • 8 citations

Regulation of Immune Responses by CD38 and cADPR

2002 • 4 citations

Chemotactic Factor Receptors and Signal Transduction

2020 • 1 citations