Sequence heterogeneities of genes encoding 16S rRNAs in Paenibacillus polymyxa detected by temperature gradient gel electrophoresis

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA

1993 • 11,277 citations

Nucleic acid techniques in bacterial systematics

1991 • 9,212 citations

Phylogenetic identification and in situ detection of individual microbial cells without cultivation

1995 • 8,157 citations

Taxonomic Note: A Place for DNA-DNA Reassociation and 16S rRNA Sequence Analysis in the Present Species Definition in Bacteriology

1994 • 6,734 citations

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations

1990 • 3,992 citations

Complete nucleotide sequence of a 16S ribosomal RNA gene from Escherichia coli.

1978 • 2,326 citations

Bacterial evolution

1987 • 2,303 citations

Fluorescent-oligonucleotide probing of whole cells for determinative, phylogenetic, and environmental studies in microbiology

1990 • 2,234 citations

Gene organization and primary structure of a ribosomal RNA operon from Escherichia coli

1981 • 1,732 citations

Genetic diversity in Sargasso Sea bacterioplankton

1990 • 1,666 citations

The ribosomal database project.

1993 • 1,574 citations

How Close Is Close: 16S rRNA Sequence Identity May Not Be Sufficient To Guarantee Species Identity

1992 • 1,305 citations

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes.

1989 • 1,295 citations

The Polymerase Chain Reaction

1990 • 1,198 citations

Compilation of small ribosomal subunit RNA sequences

1992 • 985 citations

Phylogenetic heterogeneity of the genus Bacillus revealed by comparative analysis of small-subunit-ribosomal RNA sequences

2008 • 717 citations

Lessons from an evolving rRNA: 16S and 23S rRNA structures from a comparative perspective

1994 • 673 citations

Structurally Distinct, Stage-Specific Ribosomes Occur in Plasmodium

1987 • 309 citations

Characterization of two xenopus somatic 5S DNAs and one minor oocyte-specific 5S DNA

1980 • 305 citations

Compilation of small ribosomal subunit RNA sequences

1990 • 279 citations

Intraspecific Variation in Small-Subunit rRNA Sequences in GenBank: Why Single Sequences May Not Adequately Represent Prokaryotic Taxa

1995 • 271 citations

Temperature-gradient gel electrophoresis

1987 • 236 citations

rRNA operon multiplicity in Escherichia coli and the physiological implications of rrn inactivation

1995 • 210 citations

Systematic Sequencing of the 180 Kilobase Region of the Bacillus Subtilis Chromosome Containing the Replication Origin

1994 • 203 citations

Sequence heterogeneity between the two genes encoding 16S rRNA from the halophilic archaebacterium Haloarcula marismortui.

1992 • 199 citations

Thermal denaturation of double-stranded nucleic acids: prediction of temperatures critical for gradient gel electrophoresis and polymerase chain reaction

1994 • 182 citations

The regulation of ribosomal RNA synthesis and bacterial cell growth

1994 • 166 citations

Localization and structural analysis of the ribosomal RNA operons ofRhodobacter sphaeroides

1990 • 158 citations

The Complete Nucleotide Sequence of the Ribosomal 16-S RNA from Escherichia coli. Experimental Details and Cistron Heterogeneities

1979 • 141 citations

Identification of single bacterial cells using digoxigenin-labelled, rRNA-targeted oligonucleotides

1991 • 137 citations

Amplification of ribosomal RNA genes for molecular evolution studies

1990 • 128 citations

Prokaryotic introns and inteins: a panoply of form and function

1995 • 113 citations

Bacterial genomics

1994 • 108 citations

Validation of the Publication of New Names and New Combinations Previously Effectively Published Outside the IJSB: List No. 51

1994 • 97 citations

Phylogeny of spore-forming lactic acid bacteria based on 16S rRNA gene sequences

1994 • 82 citations

AMPLIFICATION OF RIBOSOMAL RNA GENES FOR MOLECULAR EVOLUTION STUDIES

1990 • 81 citations

Cloning, mapping, and molecular characterization of the rRNA operons of Clostridium perfringens

1991 • 74 citations

Phylogenetic Diversity in the Genus Bacillus as Seen by 16S rRNA Sequencing Studies

1991 • 74 citations

Evidence for unlinked rrn operons in the Planctomycete Pirellula marina

1989 • 65 citations

Instability of rRNA operons in Bacillus subtilis

1988 • 61 citations

A comparative study of the ribosomal RNA operons ofStreptomyces coelicolorA3(2) and sequence analysis ofrrnA

1991 • 46 citations

Direct sequencing of variable HLA gene segments after in vitro amplification and allele separation by temperature-gradient gel electrophoresis

1991 • 29 citations

Divergent Evolution of 5 S rRNA Genes in Methanococcus

1987 • 13 citations

rRNA Operon Multiplicity inEscherichia coliand the Physiological Implications ofrrnInactivation

1995 • 3 citations