An Inducible Human Immunodeficiency Virus Type 1 (HIV-1) Vector Which Effectively Suppresses HIV-1 Replication

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

1996 • 4,854 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

Gene therapy - promises, problems and prospects

1997 • 1,692 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

1996 • 1,516 citations

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

1993 • 1,395 citations

Development of a Self-Inactivating Lentivirus Vector

1998 • 1,169 citations

Transfer of Genes to Humans: Early Lessons and Obstacles to Success

1995 • 1,023 citations

Dual Infection of the Central Nervous System by AIDS Viruses with Distinct Cellular Tropisms

1987 • 831 citations

Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

1997 • 614 citations

Induction of Apoptosis in Uninfected Lymphocytes by HIV-1 Tat Protein

1995 • 581 citations

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

1997 • 499 citations

Nef Harbors a Major Determinant of Pathogenicity for an AIDS-like Disease Induced by HIV-1 in Transgenic Mice

1998 • 448 citations

Intracellular immunization

1988 • 420 citations

Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles

1996 • 384 citations

Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest

1997 • 348 citations

High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G

1996 • 314 citations

High-Titer Human Immunodeficiency Virus Type 1-Based Vector Systems for Gene Delivery into Nondividing Cells

1998 • 308 citations

Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1

1998 • 263 citations

Packaging system for rapid production of murine leukemia virus vectors with variable tropism

1992 • 260 citations

Progression to AIDS in the absence of a gene for vpr or vpx

1995 • 243 citations

Human Immunodeficiency Virus Type 1 Vectors Efficiently Transduce Human Hematopoietic Stem Cells

1998 • 176 citations

Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector

1991 • 150 citations

Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1

1996 • 140 citations

Analysis in human immunodeficiency virus type 1 vectors of cis-acting sequences that affect gene transfer into human lymphocytes

1994 • 133 citations

Human immunodeficiency virus vectors for inducible expression of foreign genes

1992 • 125 citations

Human gene therapy — an immature genie, but certainly out of the bottle

1996 • 115 citations

Sequences lead to tree of worms

1998 • 106 citations

A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread.

1996 • 99 citations

Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr

1995 • 91 citations

Apoptosis induced in CD4+ cells expressing gp160 of human immunodeficiency virus type 1

1994 • 89 citations

In Vivo Pathogenesis of a Human Immunodeficiency Virus Type 1 Reporter Virus

1998 • 86 citations

Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard

1997 • 80 citations

High transdominant RevM10 protein levels are required to inhibit HIV-1 replication in cell lines and primary T cells: implication for gene therapy of AIDS

1997 • 78 citations

Transduction of human macrophages using a stable HIV-1/HIV-2-derived gene delivery system

1998 • 55 citations

High-efficiency transduction of human lymphoid progenitor cells and expression in differentiated T cells

1997 • 49 citations

Anti-HIV Effects of HIV Vectors

1998 • 45 citations

Gene therapy: hopes, hypes, and hurdles.

1994 • 29 citations

Co-packaging of sense and antisense RNAs: a novel strategy for blocking HIV-1 replication

1998 • 22 citations

Gene Therapy: Hopes, Hypes, and Hurdles

1994 • 22 citations

Inhibition of HIV-1 replication by combined expression of gag dominant negative mutant and a human ribonuclease in a tightly controlled HIV-1 inducible vector

1998 • 22 citations