Analysis in human immunodeficiency virus type 1 vectors of cis-acting sequences that affect gene transfer into human lymphocytes

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

The Role of Mononuclear Phagocytes in HTLV-III/LAV Infection

1986 • 1,828 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

1984 • 976 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

Acquired Immunodeficiency Syndrome: Epidemiologic, Clinical, Immunologic, and Therapeutic Considerations

1984 • 871 citations

[71] Use of eukaryotic expression technology in the functional analysis of cloned genes

1987 • 834 citations

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

1986 • 804 citations

Infection of monocyte/macrophages by human T lymphotropic virus type III.

1986 • 682 citations

A second post-transcriptional trans-activator gene required for HTLV-III replication

1986 • 639 citations

Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of noninfectious virus

1990 • 531 citations

Structure, Replication, and Recombination of Retrovirus Genomes: Some Unifying Hypotheses

1979 • 529 citations

Human immunodeficiency virus infection of cells arrested in the cell cycle.

1992 • 523 citations

Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region

1987 • 426 citations

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1989 • 400 citations

Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions

1989 • 372 citations

Regulation of human immunodeficiency virus env expression by the rev gene product

1989 • 365 citations

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1989 • 359 citations

Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes.

1991 • 358 citations

Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus.

1988 • 355 citations

Effect of internal viral sequences on the utility of retroviral vectors

1987 • 351 citations

Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity

1990 • 351 citations

Characterization of the reverse transcriptase from a new retrovirus (HTLV) produced by a human cutaneous T-cell lymphoma cell line

1981 • 306 citations

Functional Sites in the 5′ Region of Human Immunodeficiency Virus Type 1 RNA Form Defined Structural Domains

1993 • 294 citations

Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein

1994 • 289 citations

Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein

1992 • 276 citations

Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein

1993 • 274 citations

Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants

1990 • 268 citations

Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA.

1993 • 243 citations

Construction of a helper cell line for avian reticuloendotheliosis virus cloning vectors.

1983 • 214 citations

The human immunodeficiency virus type 1 packaging signal and major splice donor region have a conserved stable secondary structure

1992 • 205 citations

Tissue-specific transcription preference as a determinant of cell tropism and leukaemogenic potential of murine retroviruses

1984 • 202 citations

A mutant of human immunodeficiency virus with reduced RNA packaging and abnormal particle morphology

1990 • 173 citations

Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation

1991 • 168 citations

Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector

1991 • 150 citations

HIV Causes AIDS

1988 • 139 citations

Human immunodeficiency virus vectors for inducible expression of foreign genes

1992 • 125 citations

RNA packaging signal of human immunodeficiency virus type 1

1992 • 114 citations

Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein

1991 • 111 citations

Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region

1993 • 111 citations

Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector.

1991 • 105 citations

Construction of a Helper Cell Line for Avian Reticuloendotheliosis Virus Cloning Vectors

1983 • 99 citations

Replication and pathogenesis of the AIDS virus.

1988 • 96 citations

A new avian leukosis virus-based packaging cell line that uses two separate transcomplementing helper genomes

1990 • 63 citations

Replication-defective vectors of reticuloendotheliosis virus transduce exogenous genes into somatic stem cells of the unincubated chicken embryo

1989 • 57 citations

Relative importance of elements within the SL3-3 virus enhancer for T-cell specificity

1990 • 44 citations

Avian retroviral vectors derived from avian defective leukemia virus: Role of the translational context of the inserted gene on efficiency of the vectors

1989 • 33 citations

Generation of a helper cell line for packaging avian leukosis virus-based vectors

1989 • 30 citations

Deleted Work

1955 • 0 citations