Matrix Metalloproteinases in Multiple Myeloma

Changing views of the role of matrix metalloproteinases in metastasis

1997 • 1,585 citations

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

1997 • 1,311 citations

Matrix Metalloproteinase-2 Is an Interstitial Collagenase

1995 • 917 citations

Syndecans: multifunctional cell-surface co-receptors

1997 • 676 citations

Bone marrow angiogenesis and progression in multiple myeloma

1994 • 656 citations

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1997 • 612 citations

Bone Marrow Neovascularization, Plasma Cell Angiogenic Potential, and Matrix Metalloproteinase-2 Secretion Parallel Progression of Human Multiple Myeloma

1999 • 590 citations

Requirement for Specific Proteases in Cancer Cell Intravasation as Revealed by a Novel Semiquantitative PCR-Based Assay

1998 • 459 citations

Multiple Myeloma

1997 • 389 citations

Regulation of Matrix Metalloproteinases (MMP-2, -3, -9, and -13) by Interleukin-1 and Interleukin-6 in Mouse Calvaria: Association of MMP Induction with Bone Resorption*

1998 • 361 citations

Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma

1999 • 252 citations

Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.

1997 • 250 citations

Initiation of Osteoclast Bone Resorption by Interstitial Collagenase

1997 • 250 citations

Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen

1993 • 230 citations

Bone Marrow Neovascularization, Plasma Cell Angiogenic Potential, and Matrix Metalloproteinase-2 Secretion Parallel Progression of Human Multiple Myeloma

1999 • 221 citations

Matrix metalloproteinases are obligatory for the migration of preosteoclasts to the developing marrow cavity of primitive long bones

1995 • 218 citations

Syndecan-1 Is a Multifunctional Regulator of Myeloma Pathobiology: Control of Tumor Cell Survival, Growth, and Bone Cell Differentiation

1998 • 204 citations

MMP Inhibition and Downregulation by Bisphosphonates

1999 • 197 citations

Metalloproteinases in Multiple Myeloma: Production of Matrix Metalloproteinase-9 (MMP-9), Activation of proMMP-2, and Induction of MMP-1 by Myeloma Cells

1997 • 186 citations

Identification of matrix metalloproteinase 9 in rabbit osteoclasts.

1994 • 169 citations

Expression of syndecan-1 inhibits cell invasion into type I collagen.

1994 • 169 citations

The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts

1994 • 167 citations

Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth.

1994 • 160 citations

Cysteine Proteinases and Matrix Metalloproteinases Play Distinct Roles in the Subosteoclastic Resorption Zone

1998 • 135 citations

Tissue inhibitors of metalloproteinases (TEMP) in invasion and proliferation

1999 • 122 citations

Heparan Sulfate-mediated Cell Aggregation

1995 • 122 citations

Angiogenesis in B Cell Lymphoproliferative Diseases. Biological and Clinical Studies

1995 • 106 citations

Elevated levels of shed syndecan‐1 correlate with tumour mass and decreased matrix metalloproteinase‐9 activity in the serum of patients with multiple myeloma

1997 • 100 citations

The Migration of Purified Osteoclasts Through Collagen Is Inhibited by Matrix Metalloproteinase Inhibitors

1998 • 98 citations

Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis, and angiogenesis

1998 • 98 citations

Tumor Cell Intravasation Alu-cidated

1998 • 82 citations

Matrilysin in early stage intestinal tumorigenesis

1999 • 80 citations

Parathyroid hormone-induced resorption in fetal rat limb bones is associated with production of the metalloproteinases collagenase and gelatinase B

1996 • 76 citations

PATHOGENESIS AND MANAGEMENT OF BONE LESIONS IN MULTIPLE MYELOMA

1997 • 65 citations

Lack of IL‐1 secretion from human myeloma cells highly purified by immunomagnetic separation

1993 • 64 citations

Syndecan‐1 expression suppresses the level of myeloma matrix metalloproteinase‐9

1999 • 38 citations

Treatment of Osteoporosis with MMP Inhibitors

1999 • 29 citations

New insights in the clinical biology of multiple myeloma.

1997 • 17 citations