Structure and Pharmacology of Vertebrate GABAA Receptor Subtypes

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

1986 • 2,194 citations

GABA_A Receptor Channels

1994 • 1,948 citations

Molecular and cellular mechanisms of general anaesthesia

1994 • 1,779 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

1992 • 1,525 citations

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

1989 • 1,283 citations

Type I and Type II GABA _A -Benzodiazepine Receptors Produced in Transfected Cells

1989 • 716 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum

1992 • 673 citations

The effect of subunit composition of rat brain GABAA receptors on channel function

1990 • 592 citations

Structural and functional basis for GABAA receptor heterogeneity

1988 • 590 citations

Functional properties of recombinant rat GABAA receptors depend upon subunit composition

1990 • 557 citations

A point mutation in a Drosophila GABA receptor confers insecticide resistance

1993 • 552 citations

Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

1990 • 536 citations

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations

1989 • 532 citations

‘Puppet’ Children A Report on Three Cases

1965 • 521 citations

Neurosteroids act on recombinant human GABAA receptors

1990 • 515 citations

γ‐Aminobutyric Acid_A Receptor α₅‐Subunit Creates Novel Type II Benzodiazepine Receptor Pharmacology

1990 • 498 citations

Mechanism of action of ethanol: initial central nervous system actions.

1989 • 445 citations

A single histidine in GABAA receptors is essential for benzodiazepine agonist binding.

1992 • 441 citations

Regulation of neurotransmitter receptor desensitization by protein phosphorylation

1990 • 439 citations

The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor

1990 • 433 citations

Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.

1991 • 426 citations

Quaternary Structure of the Native GABA_A Receptor Determined by Electron Microscopic Image Analysis

1994 • 423 citations

GABAA receptor needs two homologous domains of the & beta;-subunit for activation by GABA but not by pentobarbital

1993 • 417 citations

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.

1990 • 415 citations

Some properties of brain specific benzodiazepine receptors: New evidence for multiple receptors

1979 • 412 citations

GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs.

1989 • 404 citations

Comparative molecular neuroanatomy of cloned GABA_Areceptor subunits in the rat CNS

1992 • 382 citations

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

1990 • 370 citations

The structure of ion channels in membranes of excitable cells

1989 • 368 citations

Pharmacology of GABA receptor CI− channels in rat retinal bipolar cells

1993 • 353 citations

Ethanol sensitivity of the GABAA receptor expressed in xenopus oocytes requires 8 amino acids contained in the γ2L subunit

1991 • 353 citations

The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones

1991 • 350 citations

Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies.

1992 • 346 citations

Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents.

1991 • 338 citations

Assembly of GABAA receptor subunits: role of the delta subunit

1994 • 335 citations

Functional Modulation of GABA _A Receptors by cAMP-Dependent Protein Phosphorylation

1992 • 322 citations

The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels.

1992 • 305 citations

Regulation of GABAA receptor function by protein kinase C phosphorylation

1994 • 304 citations

GABA _A -Receptor Function in Hippocampal Cells Is Maintained by Phosphorylation Factors

1988 • 303 citations

Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate gamma-aminobutyric acid subtype A receptor locus.

1991 • 294 citations

Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons

1988 • 271 citations

Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates.

1989 • 266 citations

Novel GABA responses from rod- driven retinal horizontal cells

1993 • 264 citations

Cloning, pharmacological characteristics and expression pattern of the rat GABA_A receptor α₄ subunit

1991 • 259 citations

A novel α subunit in rat brain GABAA receptors

1989 • 251 citations

Neurosteroid regulation of GABAA receptor single‐channel kinetic properties of mouse spinal cord neurons in culture.

1992 • 241 citations

The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit.

1994 • 235 citations

Subcellular localization of benzodiazepine/GABAA receptors in the cerebellum of rat, cat, and monkey using monoclonal antibodies

1989 • 234 citations

Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor.

1992 • 233 citations

Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture.

1989 • 225 citations

Cyclic AMP-dependent protein kinase decreases GABAA receptor current in mouse spinal neurons

1990 • 225 citations

GABA_A receptors are differentially sensitive to zinc: dependence on subunit composition

1991 • 223 citations

Assembly of GABAA receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single- channel properties

1993 • 221 citations

Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors.

1990 • 219 citations

GABAA receptors display association of γ2-subunit with α1- and β2/3-subunits

1991 • 218 citations

Propofol Activates GABAA Receptor-Chloride Ionophore Complex in Dissociated Hippocampal Pyramidal Neurons of the Rat

1993 • 217 citations

Understanding the GABAA receptor: a chemically gated ion channel

1988 • 217 citations

Neuron-specific expression of GABAA-receptor subtypes: Differential association of theα1- andα3-subunits with serotonergic and gabaergic neurons

1993 • 216 citations

Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture.

1989 • 216 citations

A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions.

1984 • 208 citations

Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels.

1992 • 203 citations

Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.

1991 • 202 citations

gamma-Aminobutyric acid A or C receptor? gamma-Aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive gamma-aminobutyric acid responses in Xenopus oocytes.

1992 • 201 citations

Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human gamma-aminobutyric acidA receptors.

1993 • 201 citations

Distribution, prevalence, and drug binding profile of gamma-aminobutyric acid type A receptor subtypes differing in the beta-subunit variant.

1994 • 200 citations

Activation of protein kinase C differentially modulates neuronal Na+, Ca2+, and gamma-aminobutyrate type A channels.

1988 • 197 citations

Generation of Two Forms of the γ‐Aminobutyric Acid_A Receptor γ‐₂‐Subunit in Mice by Alternative Splicing

1991 • 196 citations

GABAA receptor subtypes immunopurified from rat brain with α subunit-specific antibodies have unique pharmacological properties

1991 • 195 citations

Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors.

1993 • 194 citations

On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat.

1992 • 193 citations

Photoaffinity Labeling of Benzodiazepine Receptor Proteins with the Partial Inverse Agonist [³H]Ro 15–4513: A Biochemical and Autoradiographic Study

1987 • 191 citations

Enhancement of gamma‐aminobutyric acid‐activated Cl‐ currents in cultured rat hippocampal neurones by three volatile anaesthetics.

1992 • 191 citations

Identification of a putative γ-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14–q21 and mouse chromosome 4

1992 • 190 citations

The GABAA Receptor Family: Molecular and Functional Diversity

1990 • 187 citations

Ethanol potentiation of GABA_A receptors requires phosphorylation of the alternatively spliced variant of the γ2 subunit

1992 • 178 citations

Characterization of bicuculline/baclofen-insensitive (rho-like) gamma-aminobutyric acid receptors expressed in Xenopus oocytes. II. Pharmacology of gamma-aminobutyric acidA and gamma-aminobutyric acidB receptor agonists and antagonists.

1993 • 177 citations

A novel allosteric modulatory site on the GABAA receptor β subunit

1994 • 175 citations

Effects of subunit types of the cloned GABAA receptor on the response to a neurosteroid

1991 • 174 citations

Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations.

1994 • 172 citations

GABAA receptor populations with novel subunit combinations and drug binding profiles identified in brain by alpha 5- and delta-subunit-specific immunopurification.

1993 • 170 citations

Function of the alpha 1 beta 2 gamma 2S gamma-aminobutyric acid type A receptor is modulated by protein kinase C via multiple phosphorylation sites.

1992 • 167 citations

Protein kinase C and cAMP-dependent protein kinase phosphorylate the beta subunit of the purified gamma-aminobutyric acid A receptor.

1990 • 166 citations

Stoichiometry of a recombinant GABAA receptor deduced from mutation-induced rectification

1993 • 164 citations

Identification of a [3H]muscimol photoaffinity substrate in the bovine gamma-aminobutyric acidA receptor alpha subunit.

1994 • 162 citations

A novel GABA receptor on bipolar cell terminals in the tiger salamander retina

1994 • 161 citations

A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms.

1994 • 160 citations

gamma-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site.

1991 • 152 citations

Selective Allocation of GABA_A Receptors Containing the α1 Subunit to Neurochemically Distinct Subpopulations of Rat Hippocampal Interneurons

1994 • 149 citations

Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes.

1993 • 149 citations

Pharmacology of GAB A ρ1 and GAB A α/β receptors expressed in Xenopus oocytes and COS cells

1993 • 145 citations

γ‐Aminobutyric Acid_A Receptor Heterogeneity Is Increased by Alternative Splicing of a Novel β‐Subunit Gene Transcript

1991 • 144 citations

Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors.

1993 • 141 citations

General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium.

1992 • 139 citations

A novel modulatory binding site for zinc on the GABAA receptor complex in cultured rat neurones.

1992 • 132 citations

Functional expression and sites of gene transcription of a novel α subunit of the GABA_A receptor in rat brain

1990 • 131 citations

The third gamma subunit of the gamma-aminobutyric acid type A receptor family.

1992 • 129 citations

Activation of protein kinase C selectively inhibits the gamma-aminobutyric acidA receptor: role of desensitization.

1992 • 128 citations

The gamma 2 subunit is an integral component of the gamma-aminobutyric acidA receptor but the alpha 1 polypeptide is the principal site of the agonist benzodiazepine photoaffinity labeling reaction.

1990 • 124 citations

Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease

1989 • 121 citations

Model of subunit composition of gamma-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their alpha and gamma/delta subunits.

1994 • 118 citations

Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors

1991 • 115 citations

Expression patterns of gamma-aminobutyric acid type A receptor subunit mRNAs in primary cultures of granule neurons and astrocytes from neonatal rat cerebella.

1992 • 114 citations

Novel GABAA receptor α subunit is expressed only in cerebellar granule cells

1990 • 112 citations

Differential effect of zinc on the vertebrate GABA_A‐receptor complex

1990 • 112 citations

A single amino acid of the human gamma-aminobutyric acid type A receptor gamma 2 subunit determines benzodiazepine efficacy

1994 • 110 citations

Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique

1993 • 110 citations

Regional gamma-aminobutyric acid sensitivity of t-butylbicyclophosphoro[35S]thionate binding depends on gamma-aminobutyric acidA receptor alpha subunit.

1993 • 106 citations

A strong promoter element is located between alternative exons of a gene encoding the human gamma-aminobutyric acid-type A receptor beta 3 subunit (GABRB3).

1993 • 106 citations

A cluster of three GABAA receptor subunit genes is deleted in a neurological mutant of the mouse p locus

1993 • 106 citations

Identification and immunohistochemical mapping of GABA_A receptor subtypes containing the δ‐subunit in rat brain

1991 • 106 citations

Single channel currents activated by gamma-aminobutyric acid, muscimol, and (-)-pentobarbital in cultured mouse spinal neurons

1982 • 105 citations

Noradrenergic potentiation of cerebellar Purkinje cell responses to GABA: evidence for mediation through the β-adrenoceptor-coupled cyclic AMP system

1989 • 105 citations

Impact of beta and gamma variants on ligand-binding properties of gamma-aminobutyric acid type A receptors.

1994 • 105 citations

Noncompetitive inhibition of gamma-aminobutyric acidA channels by Zn.

1991 • 104 citations

cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes.

1989 • 103 citations

Immunoaffinity purification of GABAA receptor alpha-subunit iso-oligomers. Demonstration of receptor populations containing alpha 1 alpha 2, alpha 1 alpha 3, and alpha 2 alpha 3 subunit pairs.

1991 • 102 citations

Phenotypic consequences of deletion of the gamma 3, alpha 5, or beta 3 subunit of the type A gamma-aminobutyric acid receptor in mice.

1994 • 102 citations

Biochemical evidence for the existence of gamma-aminobutyrateA receptor iso-oligomers.

1990 • 100 citations

Differential Responses of Expressed Recombinant Human γ‐Aminobutyric Acid_A Receptors to Neurosteroids

1991 • 97 citations

Sequence and expression of human GABA_A receptor α1 and β1 subunits

1989 • 97 citations

The γ3‐subunit of the GABA_A‐receptor confers sensitivity to benzodiazepine receptor ligands

1991 • 94 citations

Patch-clamp measurements of elementary chloride currents activated by the putative inhibitory transmitter GABA and glycine in mammalian spinal neurons.

1983 • 92 citations

The Murine GABA_AReceptor δ-Subunit Gene: Structure and Assignment to Human Chromosome 1

1990 • 91 citations

Differential subcellular distribution of the α6 subunit versus the α1 and β2/3 subunits of the GABAA/benzodiazepine receptor complex in granule cells of the cerebellar cortex

1992 • 90 citations

The Subunit Composition of a GABA_A/Benzodiazepine Receptor from Rat Cerebellum

1994 • 89 citations

Incidence of 15q deletions in the Angelman syndrome: A survey of twelve affected persons

1989 • 88 citations

Phosphorylation factors control neurotransmitter and neuromodulator actions at the gamma-aminobutyric acid type A receptor.

1994 • 87 citations

Anaesthetic concentrations of alcohols potentiate GABAA receptor-mediated currents: lack of subunit specificity

1994 • 86 citations

Diazepam-insensitive [3H]Ro 15-4513 binding in intact cultured cerebellar granule cells

1989 • 86 citations

Few cell lines with GABAA mRNAs have functional receptors

1994 • 84 citations

GABA ρ2 receptor pharmacological profile: GABA recognition site similarities to ρ1

1993 • 83 citations

Developmental alteration in GABAA receptor structure and physiological properties in cultured cerebellar granule neurons

1994 • 81 citations

Human chromosomal localization of genes encoding the gamma 1 and gamma 2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome.

1992 • 81 citations

FISH ordering of reference markers and of the gene for the α5 subunit of the γ-aminobutyric acid receptor (GABRA5) within the Angelman and Prader–Willi syndrome chromosomal regions

1993 • 80 citations

Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor.

1992 • 79 citations

Avermectin B_1a Modulation of γ‐Aminobutyric Acid Receptors in Rat Brain Membranes

1982 • 76 citations

Immunochemical Identification of the α1- And α3–Subuntis of the Gaba_A-Receptor in Rat Brain

1991 • 76 citations

Potentiation of gamma-aminobutyric acid-mediated inhibition by isoproterenol in the cerebellar cortex: Receptor specificity

1990 • 75 citations

GABA_A-Receptors: Drug Binding Profile and Distribution of Receptors Containing the α2-Subunit in Situ

1993 • 75 citations

Effect of ivermectin on γ-aminobutyric acid-induced chloride currents in mouse hippocampal embryonic neurones

1994 • 74 citations

Studies on the mechanism of action of picrotoxinin and other convulsants at the crustacean muscle GABA receptor

1986 • 74 citations

Further evidence for the existence of alpha subunit heterogeneity within discrete gamma-aminobutyric acidA receptor subpopulations.

1993 • 73 citations

A novel γ subunit of the GABA_A receptor identified using the polymerase chain reaction

1991 • 73 citations

cAMP increases the rate of GABA_A receptor desensitization in chick cortical neurons

1989 • 70 citations

gamma-Aminobutyric acid type A receptors in the rat brain can contain both gamma 2 and gamma 3 subunits, but gamma 1 does not exist in combination with another gamma subunit.

1994 • 68 citations

Small N‐Terminal Deletion by Splicing in Cerebellar α6 Subunit Abolishes GABA_A Receptor Function

1994 • 67 citations

Irreversible Binding of [³H]Flunitrazepam to Different Proteins in Various Brain Regions

1983 • 67 citations

Developmental cues modulate GABAA receptor subunit mRNA expression in cultured cerebellar granule neurons

1993 • 67 citations

Ca²⁺/Calmodulin‐Dependent Protein Kinase II and Protein Kinase C Phosphorylate a Synthetic Peptide Corresponding to a Sequence That Is Specific for the γ_2L Subunit of the GABA_A Receptor

1993 • 66 citations

More Than one Alpha Variant May Exist in a Gaba_A/benzodiazepine Receptor Complex

1991 • 63 citations

Short and Long Form γ₂ Subunits of the GABA_A/Benzodiazepine Receptors

1994 • 63 citations

Sequence and Regional Distribution of the mRNA Encoding the α₂ Polypeptide of Rat γ‐Aminobutyric Acid_A Receptors

1991 • 63 citations

Pharmacological characterization and region‐specific expression in brain of the β2‐ and β3‐subunits of the rat GABA_A receptor

1989 • 62 citations

The GABAA receptor β3 subunit gene: Characterization of a human cDNA from chromosome 15q11q13 and mapping to a region of conserved synteny on mouse chromosome 7

1991 • 61 citations

GABA_A Receptor Subtypes Expressed in Cerebellar Granule Cells: A Developmental Study

1994 • 61 citations

Distinctive patterns of GABAA receptor subunit mRNAs in 13 cell lines

1994 • 61 citations

Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit

1994 • 60 citations

Regional variation in steroid anesthetic modulation of [35S]TBPS binding to gamma-aminobutyric acidA receptors in rat brain.

1992 • 60 citations

Immortalized hypothalamic GT1-7 neurons express functional gamma-aminobutyric acid type A receptors.

1992 • 59 citations

The influence of the γ_2L subunit on the modulation of responses to GABA_A receptor activation

1993 • 58 citations

Molecular cloning reveals the existence of a fourth γ subunit of the vertebrate brain GABA_A receptor

1993 • 58 citations

Modulation of GABAA and glycine receptors by chlormethiazole

1992 • 56 citations

High-resolution mapping of the gamma-aminobutyric acid receptor subunit beta 3 and alpha 5 gene cluster on chromosome 15q11-q13, and localization of breakpoints in two Angelman syndrome patients.

1993 • 56 citations

Isolation, characterization, and localization of human genomic DNA encoding the β1 subunit of the GABAA receptor (GABRB1)

1991 • 55 citations

Quinolones and fenbufen interact with GABAA receptor in dissociated hippocampal cells of rat

1991 • 54 citations

Trichloroethanol potentiation of γ‐aminobutyric acid‐activated chloride current in mouse hippocampal neurones

1994 • 54 citations

Chlormethiazole: neurochemical actions at the γ-aminobutyric acid receptor complex

1989 • 53 citations

Differences in the negative allosteric modulation of gamma-aminobutyric acid receptors elicited by 4'-chlorodiazepam and by a beta-carboline-3-carboxylate ester: a study with natural and reconstituted receptors.

1989 • 53 citations

Expression and pharmacology of human GABAA receptors containing γ3 subunits

1995 • 51 citations

Brain Region‐Dependent Sensitivity of GABA_A Receptor‐Mediated Responses to Modulation by Ethanol

1992 • 51 citations

Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis

1994 • 48 citations

gamma-Aminobutyric acidA receptors displaying association of gamma 3-subunits with beta 2/3 and different alpha-subunits exhibit unique pharmacological properties.

1994 • 48 citations

Molecular Determinants of General Anesthetic Action: Role of GABA_A Receptor Structure

1993 • 46 citations

Pharmacological and Electrophysiological Properties of Recombinant GABA_A Receptors Comprising the α3, β1 and γ2 Subunits

1992 • 43 citations

Identification of the GABA_A receptor subtype mRNA in human pancreatic tissue

1994 • 43 citations

The α1,α2, and α3 Subunits of GABAA Receptors: Comparison in Seizure-Prone and -Resistant Mice and during Development

1992 • 43 citations

The effects of quinolones and NSAIDs upon GABA-evoked currents recorded from rat dorsal root ganglion neurones

1991 • 42 citations

The chicken GABAA receptor α1 subunit: cDNA sequence and localization of the corresponding mRNA

1991 • 41 citations

Effects of hexachlorocyclohexanes on gamma-aminobutyric acid receptors expressed in Xenopus oocytes by RNA from mammalian brain and retina.

1992 • 41 citations

Potentiation of gamma-aminobutyric acid-induced chloride currents by various benzodiazepine site agonists with the alpha 1 gamma 2, beta 2 gamma 2 and alpha 1 beta 2 gamma 2 subtypes of cloned gamma-aminobutyric acid type A receptors.

1993 • 39 citations

General Anesthetic Action on γ‐Aminobutyric Acid—Activated Channels

1991 • 38 citations

Enhancement of recombinant gamma-aminobutyric acid type A receptor currents by chronic activation of cAMP-dependent protein kinase.

1993 • 38 citations

Polyclonal Antibodies Directed Against an Epitope Specific for the α4‐Subunit of GABA_A Receptors Identify a 67‐kDa Protein in Rat Brain Membranes

1994 • 37 citations

Quantitative Immunoprecipitation Studies with Anti-?-Aminobutyric Acid_AReceptor ?2 1?15 Cys Antibodies

1992 • 37 citations

Selective potentiation of GABA-mediated Cl− current by lanthanum ion in subtypes of cloned GABAA receptors

1992 • 34 citations

BSF1, a novel brain-specific DNA-binding protein recognizing a tandemly repeated purine DNA element in the GABAA receptor delta subunit gene.

1994 • 34 citations

gamma-Aminobutyric acidA receptor desensitization in mice spinal cord cultured neurons: lack of involvement of protein kinases A and C.

1990 • 34 citations

The cDNA sequence and chromosomal location of the murine GABAA α1 receptor gene

1991 • 34 citations

Physiological regulation of the picrotoxin receptor by gamma- butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons

1990 • 34 citations

The pharmacology of recombinant GABA_A receptors containing bovine α₁, β₁, γ_2L sub‐units stably transfected into mouse fibroblast L‐cells

1992 • 33 citations

Sequence of the chicken GABA_Areceptor γ2-subunit cDNA

1990 • 30 citations

Rapid Communication Isolation and Characterization of the Promoter of the Human GABA_A Receptor α1 Subunit Gene

1994 • 30 citations

Effects of lindane (γ-BHC) and related convulsants on GABAA receptor-operated chloride channels in frog dorsal root ganglion neurons

1994 • 22 citations

Terbium modulation of single gamma-aminobutyric acid-activated chloride channels in rat dorsal root ganglion neurons

1994 • 21 citations

Sequence of the chicken GABA_Areceptor β3-subunit cDNA

1990 • 20 citations

Evidence for the Existence of Differential O‐Glycosylated α₅‐Subunits of the γ‐Aminobutyric Acid_A Receptor in the Rat Brain

1993 • 20 citations

Cloning and Expression of a cDNA Encoding the Human GABA-A Receptor α5 Subunit

1992 • 18 citations

Indomethacin/ibuprofen-like anti-inflammatory agents selectively potentiate the gamma-aminobutyric acid-antagonistic effects of several norfloxacin-like quinolone antibacterial agents on [35S]t-butylbicyclophosphorothionate binding.

1993 • 18 citations

Substituted pyrazinones, a new class of allosteric modulators for gamma-aminobutyric acidA receptors.

1993 • 14 citations

Identification of the γ2-subunit protein in native GABAA receptors in brain

1990 • 13 citations

Sequence and Novel Distribution of the Chicken Homologue of the Mammalian γ‐Aminobutyric Acid_A Receptor γ 1 Subunit

1993 • 13 citations

Identification of the GABA_A Receptor α3 Subunit in the IMR‐32 Neuroblastoma Cell Line

1993 • 11 citations

Monoclonal Antibodies to the Human γ₂ Subunit of the GABA_A/Benzodiazepine Receptors

1995 • 9 citations