Modulation of GABAA and glycine receptors by chlormethiazole

Management of Virus Hepatitis

1964 • 2,908 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

A patch‐clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine.

1982 • 820 citations

The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors

1987 • 730 citations

Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons.

1981 • 559 citations

Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain.

1991 • 548 citations

Modulation of the GABA receptor complex by a steroid anaesthetic

1984 • 496 citations

Excitatory amino acid transmission

1987 • 430 citations

The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones

1991 • 350 citations

Modulation of the GABA_A receptor by depressant barbiturates and pregnane steroids

1988 • 296 citations

Function and pharmacology of multiple GABAA receptor subunits

1991 • 292 citations

Pentobarbitone pharmacology of mammalian central neurones grown in tissue culture.

1978 • 284 citations

Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones

1978 • 276 citations

The effect of diazepam on spinal cord activities: Possible sites and mechanisms of action

1974 • 246 citations

Modulation of the GABA _A receptor by progesterone metabolites

1987 • 245 citations

Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture.

1989 • 216 citations

Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane and ketamine in CA1 pyramidal cells in rat hippocampus

1985 • 184 citations

Potentiation of gamma‐aminobutyric‐acid‐activated chloride conductance by a steroid anaesthetic in cultured rat spinal neurones.

1987 • 169 citations

gamma-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site.

1991 • 152 citations

Potentiation of inhibition by general anaesthetics in neurones of the olfactory cortex in vitro

1980 • 150 citations

Actions of synthetic and endogenous steroids on the GABAA receptor

1987 • 146 citations

Strychnine‐sensitive glycine responses of neonatal rat hippocampal neurones.

1991 • 141 citations

Molecular and cellular mechanisms of anesthetics

1987 • 108 citations

Actions of anaesthetics and avermectin on GABA_A chloride channels in mammalian dorsal root ganglion neurones

1989 • 88 citations

Pharmacologic significance of the structural heterogeneity of the GABAA receptor-chloride ion channel complex.

1991 • 85 citations

The modulation by chlormethiazole of the GABA_A‐receptor complex in rat brain

1989 • 78 citations

DISTINCTION BETWEEN THE EFFECTS OF BARBITURATES, BENZODIAZEPINES AND PHENYTOIN ON RESPONSES TO γ‐AMINOBUTYRIC ACID RECEPTOR ACTIVATION AND ANTAGONISM BY BICUCULLINE AND PICROTOXIN

1981 • 76 citations

Pentobarbital and picrotoxin have reciprocal actions on single GABAA receptor channels

1989 • 74 citations

Two distinct interactions of barbiturates and chlormethiazole with the GABA_A receptor complex in rat cuneate nucleus in vitro

1983 • 68 citations

Neurosteroids and brain function

1991 • 66 citations

Transmitter amino acid receptors : structures, transduction, and models for drug development

1991 • 61 citations

The effects of general anaesthetics on gabaergic synaptic transmission

1987 • 58 citations

Potentiators of responses to activation of $gamma;-aminobutyric acid (GABAA) receptors

1987 • 56 citations

Cloned GABA receptors are maintained in a stable cell line: allosteric and channel properties

1990 • 56 citations

Chlormethiazole: neurochemical actions at the γ-aminobutyric acid receptor complex

1989 • 53 citations

An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells

1989 • 50 citations

Chlormethiazole‐mode of action

1986 • 43 citations

BARBITURATES

1988 • 36 citations

Chlormethiazole in treatment of status epilepticus.

1975 • 35 citations

The effects of chlormethiazole on single unit activity in rat brain; interactions with inhibitory and excitatory neurotransmitters

1983 • 24 citations

A STUDY OF THE CARDIOVASCULAR EFFECTS OF CHLORMETHIAZOLE

1969 • 24 citations

Microcomputers in Physiology: a Practical Approach

1989 • 23 citations

Determination of Chlormethiazole in Blood by High Performance Liquid Chromatography

1983 • 12 citations

Chloride channel modulation through the benzodiazepine recognition site.

1988 • 3 citations