CD72 Negatively Regulates Signaling Through the Antigen Receptor of B Cells

NK CELL RECEPTORS

1998 • 1,666 citations

Augmented humoral and anaphylactic responses in FcγRII-deficient mice

1996 • 828 citations

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1993 • 756 citations

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

1995 • 710 citations

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1993 • 578 citations

A Role in B Cell Activation for CD22 and the Protein Tyrosine Phosphatase SHP

1995 • 551 citations

Hyperresponsive B Cells in CD22-Deficient Mice

1996 • 530 citations

Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling

1997 • 505 citations

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1995 • 475 citations

Cytoplasmic Domain Heterogeneity and Functions of IgG Fc Receptors in B Lymphocytes

1992 • 462 citations

Characterization of the B Lymphocyte Populations in Lyn-Deficient Mice and the Role of Lyn in Signal Initiation and Down-Regulation

1997 • 451 citations

INITIATION AND PROCESSING OF SIGNALS FROM THE B CELL ANTIGEN RECEPTOR

1997 • 440 citations

CD22 Is Both a Positive and Negative Regulator of B Lymphocyte Antigen Receptor Signal Transduction: Altered Signaling in CD22-Deficient Mice

1996 • 437 citations

CD22 is a negative regulator of B-cell receptor signalling

1997 • 427 citations

Polygenic Autoimmune Traits: Lyn, CD22, and SHP-1 Are Limiting Elements of a Biochemical Pathway Regulating BCR Signaling and Selection

1998 • 427 citations

CD22 regulates thymus-independent responses and the lifespan of B cells

1996 • 395 citations

A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells

1997 • 325 citations

POSITIVE VERSUS NEGATIVE SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS

1998 • 320 citations

Analysis of the repertoire of anti‐NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response

1978 • 316 citations

The B-cell surface protein CD72/Lyb-2 is the ligand for CDS

1991 • 305 citations

CD22, A B LYMPHOCYTE–SPECIFIC ADHESION MOLECULE THAT REGULATES ANTIGEN RECEPTOR SIGNALING^*

1997 • 296 citations

Inhibition of the B Cell by CD22: A Requirement for Lyn

1998 • 265 citations

T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation

1999 • 210 citations

A Double-Edged Kinase Lyn: A Positive and Negative Regulator for Antigen Receptor–mediated Signals

1998 • 206 citations

Requirement of SH2-containing Protein Tyrosine Phosphatases SHP-1 and SHP-2 for Paired Immunoglobulin-like Receptor B (PIR-B)–mediated Inhibitory Signal

1998 • 205 citations

Tuning Antigen Receptor Signaling by CD22: Integrating Cues from Antigens and the Microenvironment

1997 • 195 citations

CD22 associates with the human surface IgM-B-cell antigen receptor complex.

1993 • 185 citations

Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes

1998 • 175 citations

The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation.

1998 • 157 citations

Association of CD22 with the B cell antigen receptor

1993 • 157 citations

Cutting Edge: The B Cell Surface Protein CD72 Recruits the Tyrosine Phosphatase SHP-1 upon Tyrosine Phosphorylation

1998 • 141 citations

Tyrosine Phosphorylation of CD22 During B Cell Activation

1992 • 139 citations

Molecular components of the B cell antigen receptor complex of class IgD differ partly from those of IgM.

1990 • 126 citations

The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1

1998 • 121 citations

Counterregulation by the Coreceptors CD19 and CD22 of MAP Kinase Activation by Membrane Immunoglobulin

1997 • 106 citations

Role of the CD22 human B cell antigen in B cell triggering by anti-immunoglobulin.

1988 • 102 citations

A new alloantigen expressed selectively on B cells: the Lyb-2 system

1976 • 101 citations

Identification of a novel inducible cell-surface ligand of CD5 on activated lymphocytes.

1996 • 99 citations

Amplification of human B cell activation by a monoclonal antibody to the B cell-specific antigen CD22, Bp 130/140.

1987 • 98 citations

Sequence of the Lyb-2 B-cell differentiation antigen defines a gene superfamily of receptors with inverted membrane orientation.

1989 • 88 citations

What Goes Up Must Come Down: The Emerging Spectrum of Inhibitory Receptors

1997 • 79 citations

A role for CD5 in cognate interactions between T cells and B cells, and identification of a novel ligand for CD5

1998 • 76 citations

Protein-tyrosine Phosphatase SHP-1 Is Dispensable for FcγRIIB-mediated Inhibition of B Cell Antigen Receptor Activation

1997 • 73 citations

Co-receptors of B lymphocytes

1997 • 73 citations

Antigen receptor-mediated B cell death is blacked by signaling via CD72 or treatment with dextran sukfate and is defective in autoimmunity-prone mice

1996 • 59 citations

Activation of Lyn, Blk, and Btk But Not Syk in CD72-Stimulated B Lymphocytes

1998 • 51 citations

Activation of B lymphocytes by monovalent anti-Lyb-2 antibodies.

1984 • 50 citations

A role for Lyb-2 in B cell activation mediated by a B cell stimulatory factor.

1986 • 35 citations

Biochemical identity of the mouse Ly-19.2 and Ly-32.2 alloantigens with the B cell differentiation antigen Lyb-2/CD72.

1993 • 19 citations

Modulation of CD72 by ligation of B cell receptor complex molecules on CD5+ B cells

1997 • 13 citations