Exploiting Type 3 Complement Receptor for TNF-α Suppression, Immune Evasion, and Progressive Pulmonary Fungal Infection

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product

1999 • 3,364 citations

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

1999 • 2,088 citations

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

1999 • 1,905 citations

Immunity to fungal infections

2011 • 1,737 citations

Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)

1999 • 1,570 citations

ENDOCYTOSIS AND MOLECULAR SORTING

1996 • 1,537 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 1,525 citations

Biostatistics: A Methodology for the Health Sciences.

1995 • 985 citations

Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells

2001 • 800 citations

Immunity to fungal infections

2003 • 731 citations

Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes

1999 • 669 citations

Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes.

1983 • 495 citations

Quantitation of Dihydropyrimidine Dehydrogenase Expression by Real-Time Reverse Transcription Polymerase Chain Reaction

2000 • 345 citations

Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production

2002 • 321 citations

Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice.

1996 • 319 citations

Antibody immunity and invasive fungal infections

1995 • 282 citations

Regulation of Interleukin-12 by Complement Receptor 3 Signaling

1997 • 280 citations

The mouse macrophage receptor for C3bi (CR3) is a major mechanism in the phagocytosis of Leishmania promastigotes.

1985 • 258 citations

Exacerbation of murine listeriosis by a monoclonal antibody specific for the type 3 complement receptor of myelomonocytic cells. Absence of monocytes at infective foci allows Listeria to multiply in nonphagocytic cells.

1989 • 232 citations

Divergent Response to LPS and Bacteria in CD14-Deficient Murine Macrophages

2000 • 227 citations

Primary amines inhibit recycling of α2M receptors in fibroblasts

1980 • 213 citations

Integrin-mediated localization of Bordetella pertussis within macrophages: role in pulmonary colonization.

1991 • 201 citations

The third component of complement (C3) is responsible for the intracellular survival of Leishmania major

1987 • 198 citations

Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8+ T Cells

2003 • 180 citations

Blockade of endogenous TNF-alpha exacerbates primary and secondary pulmonary histoplasmosis by differential mechanisms.

1998 • 167 citations

More Is Not Necessarily Better: Prozone-Like Effects in Passive Immunization with IgG

2003 • 164 citations

Phagocytosis of Histoplasma capsulatum yeasts and microconidia by human cultured macrophages and alveolar macrophages. Cellular cytoskeleton requirement for attachment and ingestion.

1990 • 153 citations

Antibodies to Cryptococcus neoformans glucuronoxylomannan enhance antifungal activity of murine macrophages

1995 • 153 citations

Blockade of Endogenous TNF-α Exacerbates Primary and Secondary Pulmonary Histoplasmosis by Differential Mechanisms

1998 • 151 citations

TNF and TNFR biology in health and disease.

2001 • 148 citations

Targeted Gene Disruption Reveals an Adhesin Indispensable for Pathogenicity of Blastomyces dermatitidis

1999 • 146 citations

Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B

1994 • 140 citations

The WI-1 antigen of Blastomyces dermatitidis yeasts mediates binding to human macrophage CD11b/CD18 (CR3) and CD14.

1995 • 127 citations

Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 (CD11b/CD18).

1992 • 104 citations

Nonparametric Statistical Inference, 3rd edn.

1993 • 104 citations

Mutation of the WI-1 gene yields an attenuated Blastomyces dermatitidis strain that induces host resistance

2000 • 89 citations

A C‐terminal EGF‐like domain governs BAD1 localization to the yeast surface and fungal adherence to phagocytes, but is dispensable in immune modulation and pathogenicity of Blastomyces dermatitidis

2003 • 87 citations

Mouse model of pulmonary blastomycosis: utility, simplicity, and quantitative parameters.

1978 • 83 citations

The Differential Roles of LFA-1 and Mac-1 in Host Defense Against Systemic Infection with Streptococcus pneumoniae

2001 • 81 citations

BAD1, an Essential Virulence Factor ofBlastomyces dermatitidis, Suppresses Host TNF-α Production Through TGF-β-Dependent and -Independent Mechanisms

2002 • 74 citations

Targeting to Fcγ Receptors, But Not CR3 (CD11b/CD18), Increases Clearance ofBordetella pertussis

2001 • 68 citations

The WI-1 Adhesin Blocks Phagocyte TNF-α Production, Imparting Pathogenicity on Blastomyces dermatitidis

2001 • 68 citations

Requisite Elements in Vaccine Immunity to Blastomyces dermatitidis: Plasticity Uncovers Vaccine Potential in Immune-Deficient Hosts

2002 • 65 citations

Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF

2001 • 63 citations

Purification and characterization of the major antigen WI-1 from Blastomyces dermatitidis yeasts and immunological comparison with A antigen

1994 • 47 citations

Immunogenicity and Protective Efficacy of the WI-1 Adhesin ofBlastomyces dermatitidis

1998 • 43 citations

The taming of IL-12: suppressing the production of proinflammatory cytokines

1999 • 40 citations

Altered expression of surface protein WI-1 in genetically related strains of Blastomyces dermatitidis that differ in virulence regulates recognition of yeasts by human macrophages

1994 • 35 citations

Investigation of Anti–WI‐1 Adhesin Antibody‐Mediated Protection in Experimental Pulmonary Blastomycosis

2000 • 25 citations

Roles of neutrophil β2 integrins in kinetics of bacteremia, extravasation, and tick acquisition of Anaplasma phagocytophila in mice

2003 • 23 citations

Purification in Quantity of the Secreted Form of WI-1: A Major Adhesin onBlastomyces dermatitidisYeasts

1997 • 13 citations