Influence of acute hyperglycemia in human sepsis on inflammatory cytokine and counterregulatory hormone concentrations

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

1992 • 12,726 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference

1992 • 4,689 citations

Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans

2002 • 1,839 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis.

1992 • 942 citations

Dose-response characteristics for effects of insulin on production and utilization of glucose in man

1981 • 712 citations

The grading of sepsis

1983 • 381 citations

Alterations in fuel metabolism in critical illness: hyperglycaemia

2001 • 379 citations

Ascorbate Restores Endothelium-Dependent Vasodilation Impaired by Acute Hyperglycemia in Humans

2001 • 321 citations

Glucose-Dependent Interleukin 6 and Tumor Necrosis Factor Production by Human Peripheral Blood Monocytes In Vitro

1996 • 249 citations

Effects of isoenergetic glucose-based or lipid-based parenteral nutrition on glucose metabolism, de novo lipogenesis, and respiratory gas exchanges in critically ill patients

1998 • 208 citations

Metabolic response to sepsis and trauma

1989 • 176 citations

Review: The Role of Cytokines in the Catabolic Consequences of Infection and Injury

1998 • 166 citations

Intestinal endotoxemia as a pathogenetic mechanism in liver failure

2002 • 158 citations

Altered Responsiveness to Cortisol, Epinephrine, and Glucagon in Insulin-infused Juvenile-onset Diabetics: A Mechanism for Diabetic Instability

1980 • 134 citations

Glucose‐induced release of tumour necrosis factor‐alpha from human placental and adipose tissues in gestational diabetes mellitus

2001 • 128 citations

Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans

2002 • 116 citations

Catabolic response to stress and potential benefits of nutrition support

2002 • 114 citations

The Effect of Glucose and Advanced Glycosylation End Products on IL‐6 Production by Human Monocytes

1994 • 107 citations

Elevated Glucose Levels Stimulate Transforming Growth Factor-β1 (TGF-β1), Suppress Interleukin IL-2, IL-6 and IL-10 Production and DNA Synthesis in Peripheral Blood Mononuclear Cells

1996 • 105 citations

Substrate utilization/insulin resistance in sepsis/trauma

1997 • 81 citations

Clinical Potential of Insulin Therapy in Critically Ill Patients

2003 • 79 citations

Glucose modulates hemodynamic, metabolic, and inflammatory responses to lipopolysaccharide in rabbits

1997 • 73 citations

The role of endotoxin, TNF-α, and IL-6 in inducing the state of growth hormone insensitivity

2002 • 72 citations

Selective impairment of glucose storage in human sepsis

1999 • 47 citations

Current concept of pathogenesis of severe acute pancreatitis

2000 • 42 citations

Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultured rat hepatocytes

2001 • 39 citations

Enteral nutrition and acute pancreatitis

2001 • 29 citations

Increased Synthesis of Tumor Necrosis Factor-α in Uterine Explants From Pregnant Diabetic Rats and in Primary Cultures of Uterine Cells in High Glucose

1997 • 28 citations

Endocrine Problems in the Chronically Critically Ill Patient

2001 • 28 citations

In-Patient Hyperglycemia—Are We Ready to Treat It Yet?

2002 • 28 citations

Elevated cytosolic calcium and impaired proliferation of B lymphocytes in type II diabetes mellitus

1997 • 27 citations

The effects of 3-hydroxybutyrate and glucose on human T cell responses toCandida albicans

1993 • 16 citations

Abnormalities in glucose metabolism and their relevance to nutrition support in the critically ill.

1998 • 15 citations

Treatment revisited and factors affecting prognosis of severe acute pancreatitis

2000 • 8 citations

Glucose regulates the expression of Gi-proteins in cultured BC3H-1 myocytes

1992 • 3 citations