Induction of Skin Fibrosis in Mice Expressing a Mutated Fibrillin-1 Gene

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Fibrogenic cytokines and connective tissue production

1994 • 425 citations

Gene vaccination: plasmid DNA is more than just a blueprint

1998 • 359 citations

Antigen Presentation by Dendritic Cells after Immunization with DNA Encoding a Major Histocompatibility Complex Class II–restricted Viral Epitope

1997 • 326 citations

High Titers of Autoantibodies to Topoisomerase I (Scl-70) in Sera from Scleroderma Patients

1986 • 307 citations

Interleukin‐1, Interleukin‐2, Interleukin‐4, Interleukin‐6, Tumor Necrosis Factor α, and Interferon‐γ Levels in Sera from Patients With Scleroderma

1992 • 303 citations

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation.

1996 • 290 citations

Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton.

1976 • 279 citations

Increased prevalence of systemic sclerosis in a native american tribe in oklahoma. Association with an amerindian HLA haplotype

1996 • 219 citations

Genetic Immunization Against the Human Thyrotropin Receptor Causes Thyroiditis and Allows Production of Monoclonal Antibodies Recognizing the Native Receptor

1998 • 212 citations

Autoantibodies to the Extracellular Matrix Microfibrillar Protein, Fibrillin-1, in Patients with Scleroderma and Other Connective Tissue Diseases

1999 • 132 citations

The Tight Skin Mouse: Demonstration of Mutant Fibrillin-1 Production and Assembly into Abnormal Microfibrils

1998 • 116 citations

Association of microsatellite markers near the fibrillin 1 gene on human chromosome 15q with scleroderma in a Native American population

1998 • 103 citations

Increased collagen biosynthesis and increased expression of type I and type III procollagen genes in tight skin (TSK) mouse fibroblasts.

1986 • 98 citations

Antitopoisomerase I monoclonal autoantibodies from scleroderma patients and tight skin mouse interact with similar epitopes.

1992 • 96 citations

The Cyclopean Ear: A New Sense for the Praying Mantis

1986 • 86 citations

Induction of Skin Fibrosis and Autoantibodies by Infusion of Immunocompetent Cells from Tight Skin Mice into C57BL/6 Pa/Pa Mice

1993 • 74 citations

Early phenotypic activation of circulating helper memory T cells in scleroderma: correlation with disease activity.

1993 • 65 citations

Spontaneous Occurrence of Anti-Fibrillin-1 Autoantibodies in Tight-Skin Mice

1998 • 62 citations

Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin 1, in patients with localized scleroderma

1999 • 51 citations

B-cell Deficiency does not Abrogate Development of Cutaneous Hyperplasia in Mice Inheriting the Defective Fibrillin-1 Gene

1997 • 50 citations

Congenital fascial dystrophy: Stiff skin syndrome—a human counterpart of the tight-skin mouse

1989 • 48 citations

Autoantibodies in scleroderma and tightskin mice

1994 • 45 citations

Collagenous abnormalities in the heart of the tight-skin mouse1

1987 • 45 citations

Characterization of mutated protein encoded by partially duplicated fibrillin-1 gene in tight skin (TSK) mice

1999 • 44 citations

The tight-skin mouse: physical and biochemical properties of the skin.

1983 • 40 citations

Correlation between the Concentration of Serum Anti-topoisomerase I Autoantibodies and Histological and Biochemical Alterations in the Skin of Tight Skin Mice

1996 • 35 citations

Protective Cellular Immunity Against Influenza VirusInduced by Plasmid Inoculation of Newborn Mice

1997 • 26 citations

Structure of the Mutant Fibrillin-1 Gene in the Tight Skin (TSK) Mouse

1997 • 25 citations

Fibrillin genes map to regions of conserved mouse/human syntenyon mouse chromosomes 2 and 18

1993 • 22 citations

Glycosaminoglycan Content in Skin of the Tight‐Skin Mouse

1983 • 21 citations

Connective tissue metabolism including cytokines in scleroderma

1991 • 13 citations

Tight-Skin (Tsk) Maps on Mouse Chromosome 2 within the Region of Linkage Homology with Human Chromosome 15

1994 • 10 citations

Genetic Defects in Tight Skin Mice Developing a Scleroderma-Like Syndrome

1999 • 3 citations