Autoantibodies in scleroderma and tightskin mice

Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma

1985 • 803 citations

Defining criteria for autoimmune diseases (Witebsky's postulates revisited)

1993 • 781 citations

Demonstration of a thrombocytopenic factor in the blood of patients with thrombocytopenic purpura

1952 • 605 citations

Cellular infiltrates in scleroderma skin

1977 • 356 citations

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

1992 • 340 citations

High Titers of Autoantibodies to Topoisomerase I (Scl-70) in Sera from Scleroderma Patients

1986 • 307 citations

Clinical and Prognostic Associations Based on Serum Antinuclear Antibodies in Japanese Patients with Systemic Sclerosis

1994 • 281 citations

Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton.

1976 • 279 citations

Clinical and laboratory associations of anticentromere antibody in patients with progressive systemic sclerosis

1984 • 232 citations

Clinical associations of anticentromere antibodies and antibodies to topoisomerase i. a study of 355 patients

1988 • 223 citations

CENP‐F is a ca 400 kDa kinetochore protein that exhibits a cell‐cycle dependent localization

1993 • 220 citations

Three human chromosomal autoantigens are recognized by sera from patients with anti-centromere antibodies.

1986 • 206 citations

Autoantibody Reactive with RNA Polymerase III in Systemic Sclerosis

1993 • 204 citations

Autoantibody to U3 Nucleolar Ribonucleoprotein (Fibrillarin) In Patients with Systemic Sclerosis

1992 • 180 citations

Prognostic significance of anticentromere antibodies and anti–topoisomerase i antibodies in Raynaud's disease. A prospective study

1991 • 155 citations

Autoantibody reactive with three classes of RNA polymerases in sera from patients with systemic sclerosis.

1993 • 154 citations

Determination of an epitope of the diffuse systemic sclerosis marker antigen DNA topoisomerase I: sequence similarity with retroviral p30gag protein suggests a possible cause for autoimmunity in systemic sclerosis.

1989 • 132 citations

HOMOLOGOUS DISEASE IN THE ADULT RAT, A MODEL FOR AUTOIMMUNE DISEASE

1963 • 131 citations

Bleomycin-induced scleroderma.

1980 • 126 citations

Racial differences in the distribution of systemic sclerosis–related serum antinuclear antibodies

1994 • 124 citations

Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B.

1987 • 103 citations

Characterization of a spontaneous disease of white leghorn chickens resembling progressive systemic sclerosis (scleroderma).

1981 • 103 citations

Increased collagen biosynthesis and increased expression of type I and type III procollagen genes in tight skin (TSK) mouse fibroblasts.

1986 • 98 citations

Antitopoisomerase I monoclonal autoantibodies from scleroderma patients and tight skin mouse interact with similar epitopes.

1992 • 96 citations

A long‐term longitudinal study of anticentromere antibodies

1984 • 90 citations

Induction of Skin Fibrosis and Autoantibodies by Infusion of Immunocompetent Cells from Tight Skin Mice into C57BL/6 Pa/Pa Mice

1993 • 74 citations

PATIENTS WITH ANTICENTROMERE ANTIBODIES, CLINICAL FEATURES, DIAGNOSES AND EVOLUTION

1993 • 70 citations

Antibodies to distinct polypeptides of RNA polymerase I in sera from patients with rheumatic autoimmune disease.

1982 • 70 citations

The Molecular Pathology of Autoimmune Diseases

1993 • 66 citations

Detection of anticentromere antibodies using cloned autoantigen cenp‐Bl

1987 • 56 citations

Autoantibodies directed against different classes of Fc gamma R are found in sera of autoimmune patients.

1993 • 53 citations

Autoantibodies to topoisomerase I (Scl-70): Analysis by gel diffusion, immunoblot, and enzyme-linked immunosorbent assay

1990 • 51 citations

Antifibrillarin autoantibodies present in systemic sclerosis and other connective tissue diseases interact with similar epitopes.

1995 • 51 citations

Connective Tissue Disease and Autoantibodies in the Kindreds of 63 Patients with Systemic Sclerosis

1993 • 48 citations

Use of molecular cloning methods to map the distribution of epitopes on topoisomerase I (Scl‐70) recognized by sera of scleroderma patients

1990 • 47 citations

Anti-centromere antibodies (ACA) in systemic sclerosis patients and their relatives: a serological and HLA study

1994 • 46 citations

Autoantigenic epitopes on dna topoisomerase i

1993 • 45 citations

IgM anti-Fc gamma R autoantibodies trigger neutrophil degranulation.

1991 • 45 citations

Evidence for autoimmunity in the tight skin mouse model of systemic sclerosis

1991 • 41 citations

The igg, igm, and iga isotypes of anti‐topoisomerase i and anticentromere autoantibodies

1990 • 39 citations

Autoimmune mice make anti-Fc gamma receptor antibodies.

1990 • 37 citations

Tight-Skin Mouse an Experimental Model for Scleroderma

1994 • 35 citations

Adoptive Transfer of tsk Skin Fibrosis to +/+ Recipients by tsk Bone Marrow and Spleen Cells

1989 • 33 citations

Immunochemical and molecular characterization of anti-RNA polymerase I autoantibodies produced by tight skin mouse.

1993 • 32 citations

Anticentromere Autoantibodies

1994 • 31 citations

A long-term longitudinal isotypic study of anti-topoisomerase I autoantibodies

1992 • 30 citations

An antigenic region of topoisomerase I in DNA polymerase chain reaction-generated fragments recognized by autoantibodies of scleroderma patients

1991 • 30 citations

Association of anti-centromere and anti-Scl 70 antibodies in scleroderma. Report of two cases.

1985 • 28 citations

An approach to experimental scleroderma, using urinary glycosaminoglycans from patients with systemic scleroderma

1975 • 26 citations

Monoclonal Antibodies to Heparan Sulfate Inhibit the Formation of Thrombin-Antithrombin III Complexes

1993 • 26 citations

Self-reactive repertoire of tight skin (TSK/+) mouse: Immunochemical and molecular characterization of anti-cellular autoantibodies

1992 • 25 citations

Differential isotype recognition of two centromere associated polypeptides by immunoblotting in connective tissue disease.

1988 • 23 citations

A Trypanosoma cruzi membrane protein shares an epitope with a lymphocyte activation antigen and induces crossreactive antibodies.

1992 • 22 citations

Antibody specificities of Thai and Australian scleroderma sera with topoisomerase I recombinant fusion proteins.

1993 • 21 citations

Analysis of an immunodominant epitope of topoisomerase I in patients with systemic sclerosis

1992 • 17 citations

An FcγRIII (CD16)-specific autoantibody from a patient with progressive systemic sclerosis

1993 • 17 citations

B-cell epitopes of scleroderma-specific autoantigens

1992 • 16 citations

Analysis of human antitopoisomerase-I idiotypes.

1993 • 14 citations

Tight-skin mouse autoantibody repertoire: Analysis of VH and VK gene usage

1993 • 14 citations

Eukaryotic Expression of Recombinant Human Centromere Autoantigen and its use in a Novel ELISA for Diagnosis of CREST Syndrome

1994 • 14 citations

Isotype analysis of the anti–CENP‐B anticentromere autoantibody: Evidence for restricted clonality

1989 • 13 citations

Frequencies of scleroderma-realted autoantibodies in patients meeting the American Collage of Rheumatology criteria for system sclerosis:replay

1993 • 12 citations

The pathogenesis of systemic sclerosis.

1989 • 12 citations

Idiotypic Analysis of Human Anticentromere Autoantibodies

1991 • 5 citations

Protein blot assays specific for the discrimination of the centromere autoantigen, CENP‐A, from human cells

1993 • 4 citations