Repair of individual DNA strands in the hamster dihydrofolate reductase gene after treatment with ultraviolet light, alkylating agents, and cisplatin.

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1987 • 1,235 citations

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

THE BIOLOGY OF THE (6–4) PHOTOPRODUCT

1989 • 604 citations

Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

1989 • 576 citations

The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes

1987 • 533 citations

The Chemical Effects ofNucleic Acid Alkylation and Their Relation to Mutagenesis and Carcinogen esis

1975 • 446 citations

Nonsense mutations in the dihydrofolate reductase gene affect RNA processing.

1989 • 367 citations

THE RELATIVE CYTOTOXICITY OF(6–4) PHOTOPRODUCTS AND CYCLOBUTANE DIMERS IN MAMMALIAN CELLS*

1988 • 353 citations

UV MUTAGENIC PHOTOPRODUCTS IN Escherichia coli AND HUMAN CELLS: A MOLECULAR GENETICS PERSPECTIVE ON HUMAN SKIN CANCER*

1988 • 236 citations

Site-specific DNA repair at the nucleosome level in a yeast minichromosome

1990 • 227 citations

Gene specific DNA repair

1991 • 181 citations

Induction and repair of DNA cross-links in chinese hamster ovary cells treated with various platinum coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity.

1984 • 170 citations

Cell Cycle-Dependent Strand Bias for UV-Induced Mutations in the Transcribed Strand of Excision Repair-Proficient Human Fibroblasts but Not in Repair-Deficient Cells

1991 • 169 citations

DNA strand specificity for UV-induced mutations in mammalian cells.

1989 • 169 citations

Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells.

1991 • 157 citations

Processing of psoralen adducts in an active human gene: Repair and replication of DNA containing monoadducts and interstrand cross-links

1987 • 151 citations

Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line.

1981 • 139 citations

Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts.

1992 • 130 citations

Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene.

1990 • 128 citations

Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli.

1985 • 124 citations

Escherichia coli DNA photolyase is a flavoprotein

1984 • 123 citations

Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor.

1991 • 110 citations

Preferential repair of DNA damage on the transcribed strand of the human metallothionein genes requires RNA polymerase II

1991 • 108 citations

Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene.

1989 • 105 citations

Characterization of a DNA repair domain containing the dihydrofolate reductase gene in Chinese hamster ovary cells.

1986 • 105 citations

Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene

1991 • 100 citations

Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells

1989 • 94 citations

Escherichia coli DNA photolyase reverses cyclobutane pyrimidine dimers but not pyrimidine-pyrimidone (6-4) photoproducts.

1985 • 91 citations

Structure of the dihydrofolate reductase gene in Chinese hamster ovary cells

1983 • 87 citations

Differential repair of DNA damage in the human metallothionein gene family.

1988 • 70 citations

DNA Repair and Its Pathogenetic Implications

1990 • 69 citations

DNA repair in the metallothionein gene increases with transcriptional activation

1987 • 65 citations

General method for quantifying base adducts in specific mammalian genes.

1988 • 63 citations

Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells.

1990 • 63 citations

Preferential repair of damage in actively transcribed DNA sequences in vivo

1989 • 56 citations

Preferential DNA repair of alkali-labile sites within the active insulin gene.

1990 • 37 citations

DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice.

1991 • 35 citations

Loss of intragenomic DNA repair heterogeneity with cellular differentiation.

1991 • 29 citations

A procedure for the preparation of RNA-free plasmid DNA.

1988 • 22 citations

DNA strand-specific mutations induced by (+/-)-3 alpha,4 beta-dihydroxy- 1 alpha,2 alpha-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene in the dihydrofolate reductase gene.

1991 • 21 citations

Two expressed human genes sustain slightly more DNA damage after alkylating agent treatment than an inactive gene

1991 • 19 citations