In vivo and in vitro interaction of high and low molecular weight single-chain urokinase-type plasminogen activator with rat liver cells.

Chapter 4 Preparation of Isolated Rat Liver Cells

1976 • 5,335 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase.

1985 • 731 citations

Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

1990 • 624 citations

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1991 • 578 citations

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes.

1990 • 480 citations

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.

1985 • 450 citations

In vivo and in vitro uptake and degradation of acetylated low density lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells.

1983 • 396 citations

Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1.

1990 • 374 citations

The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants.

1990 • 278 citations

Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells

1991 • 275 citations

A 55,000-60,000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification.

1988 • 275 citations

Surface receptors for urokinase plasminogen activator

1988 • 222 citations

Identification and characterization of human endothelial cell membrane binding sites for tissue plasminogen activator and urokinase.

1990 • 150 citations

Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type 1 mRNA in rat tissues in vivo.

1990 • 150 citations

Proteolytic cleavage of single-chain pro-urokinase induces conformational change which follows activation of the zymogen and reduction of its high affinity for fibrin.

1985 • 138 citations

Purification of human fibroblast urokinase proenzyme and analysis of its regulation by proteases and protease nexin.

1984 • 134 citations

Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator.

1986 • 114 citations

Characterization of the interaction in vivo of tissue-type plasminogen activator with liver cells.

1988 • 96 citations

Quantitation of urokinase antigen in plasma and culture media by use of an elisa

1986 • 94 citations

Biological and Thrombolytic Properties of Proenzyme and Active Forms of Human Urokinase – II. Turnover of Natural and Recombinant Urokinase in Rabbits and Squirrel Monkeys

1984 • 66 citations

The interaction in vivo of transferrin and asialotransferrin with liver cells

1987 • 55 citations

Fibrinolytic properties of single chain urokinase-type plasminogen activator (Pro-urokinase)

1990 • 49 citations

Pharmacokinetics of single chain forms of urokinase-type plasminogen activator.

1987 • 29 citations

Different receptors mediate the hepatic catabolism of tissue-type plasminogen activator and urokinase

1990 • 28 citations

Mechanism of glucagon stimulation of fructose‐1,6‐bisphosphatase in rat hepatocytes

1986 • 27 citations

Characterization and fibrin-binding properties of different molecular forms of pro-urokinase from a monkey kidney cell culture

1986 • 27 citations

Evidence for the existence of at least two different binding sites for 5HT-reuptake inhibitors within the 5HT-reuptake system from human platelets

1988 • 26 citations

Thrombolytic properties of human tissue-type plasminogen activator, single-chain urokinase-type plasminogen activator, and synergistic combinations in venous thrombosis models in dogs and rabbits

1989 • 22 citations

Studies on Metabolism of Urokinase and Mechanism of Thrombolysis by Urokinase

1979 • 18 citations

Effect of deletion of epidermal growth factor-like domain on plasma clearance of pro-urokinase

1989 • 15 citations

Identification of the inhibitor of the plasminogen activator as the major protein secreted by endothelial rat liver cells

1989 • 13 citations

Pharmacokinetic properties of mutants of recombinant single chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160

1990 • 6 citations