Characterization of the interaction in vivo of tissue-type plasminogen activator with liver cells.

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

1955 • 4,109 citations

10 Methoden der enzymatischen Analyse

2019 • 3,602 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

1983 • 1,241 citations

[1] Analysis of sugars found in glycoproteins

1966 • 1,219 citations

Purification and characterization of the plasminogen activator secreted by human melanoma cells in culture.

1981 • 792 citations

In vivo and in vitro uptake and degradation of acetylated low density lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells.

1983 • 396 citations

Cathepsin L

1977 • 341 citations

An electron microscope autoradiographic study of the carbohydrate recognition systems in rat liver. I. Distribution of 125I-ligands among the liver cell types.

1979 • 310 citations

Purification and partial characterization of plasminogen activator from human uterine tissue

1979 • 282 citations

Thrombolysis by human tissue plasminogen activator and urokinase in rabbits with experimental pulmonary embolus

1981 • 254 citations

Tissue Plasminogen Activator: Chemical and Physiological Aspects

1984 • 210 citations

Turnover of Human Extrinsic (Tissue-Type) Plasminogen Activator in Rabbits

1981 • 184 citations

Purification and Characterization of a Melanoma Cell Plasminogen Activator

1983 • 155 citations

Tissue-type plasminogen activator binding to human endothelial cells. Evidence for two distinct binding sites.

1988 • 118 citations

Purification and identification of two structural variants of porcine tissue plasminogen activator by affinity adsorption on fibrin

1982 • 116 citations

Unique distribution of glycoprotein receptors on parenchymal and sinusoidal cells of rat liver.

1979 • 111 citations

Catabolism of human tissue plasminogen activator in mice

1985 • 108 citations

Pharmacokinetics and thrombolytic properties of deletion mutants of human tissue-type plasminogen activator in rabbits

1988 • 91 citations

Hepatic Clearance of Tissue-Type Plasminogen Activator in Rats

1985 • 88 citations

A tissue-type plasminogen activator mutant with prolonged clearance in vivo. Effect of removal of the growth factor domain.

1988 • 88 citations

Binding of tissue plasminogen activator to human umbilical vein endothelial cells

1987 • 77 citations

Appearance of Autolysosomes in Rat Liver after Leupeptin Treatment

1982 • 76 citations

Structure-function analysis with tissue-type plasminogen activator. Effect of deletion of NH2-terminal domains on its biochemical and biological properties.

1988 • 72 citations

The effect of a water-soluble tris-galactoside-terminated cholesterol derivative on the fate of low density lipoproteins and liposomes.

1985 • 67 citations

Clearance of the heavy and light polypeptide chains of human tissue-type plasminogen activator in rats

1986 • 58 citations

Isolation and characterization of three different carbohydrate chains from melanoma tissue plasminogen activator

1987 • 58 citations

Turnover of tissue plasminogen activator in normal and hepatectomized rabbits

1985 • 58 citations

Cellular catabolism of recombinant tissue-type plasminogen activator. Identification and characterization of a novel high affinity uptake system on rat hepatocytes.

1987 • 56 citations

The interaction in vivo of transferrin and asialotransferrin with liver cells

1987 • 55 citations

Specific targeting of high density lipoproteins to liver hepatocytes by incorporation of a tris-galactoside-terminated cholesterol derivative.

1985 • 54 citations

New approaches to thrombolytic therapy.

1984 • 43 citations

Turnover of human tissue plasminogen activator (tpa) in rabbits

1986 • 27 citations

Advances in biotechnological processes, vol. 2

1984 • 17 citations

Circulatory metabolism of recombinant tissue-type plasminogen activator in monkeys and rabbits

1988 • 11 citations

Production and preliminary characterization of monoclonal antibodies to rat plasma fibronectin

1982 • 4 citations