TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1993 • 6,762 citations

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

2006 • 5,928 citations

El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis

2000 • 4,924 citations

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

1994 • 3,959 citations

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

2006 • 2,449 citations

TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

2007 • 821 citations

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

2001 • 660 citations

Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease

2007 • 468 citations

TDP-43 Binds Heterogeneous Nuclear Ribonucleoprotein A/B through Its C-terminal Tail

2005 • 440 citations

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

2007 • 415 citations

Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2–21.3

2006 • 388 citations

A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia

2006 • 348 citations

UBIQUITIN-IMMUNOREACTIVE INTRANEURONAL INCLUSIONS IN AMYOTROPHIC LATERAL SCLEROSIS

1991 • 321 citations

Linkage of Familial Amyotrophic Lateral Sclerosis With Frontotemporal Dementia to Chromosome 9q21-q22

2000 • 316 citations

TDP-43 is deposited in the Guam parkinsonism-dementia complex brains

2007 • 231 citations

Frontotemporal lobar degeneration with motor neuron disease-type inclusions predominates in 76 cases of frontotemporal degeneration

2004 • 186 citations

Identification of Two Novel Loci for Dominantly Inherited Familial Amyotrophic Lateral Sclerosis

2003 • 131 citations

A Novel CpG-free Vertebrate Insulator Silences the Testis-specific SP-10 Gene in Somatic Tissues

2007 • 105 citations

Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions

2007 • 100 citations

Familial amyotrophic lateral sclerosis

1997 • 96 citations

Two Families with Familial Amyotrophic Lateral Sclerosis Are Linked to a Novel Locus on Chromosome 16q

2003 • 85 citations

Neuronal inclusion protein TDP-43 has no primary genetic role in FTD and ALS

2008 • 82 citations

TAR-DNA Binding Protein 43 in Pick Disease

2008 • 79 citations

Progress in the pathogenesis of amyotrophic lateral sclerosis

2001 • 62 citations

TDP-43 gene analysis in frontotemporal lobar degeneration

2007 • 45 citations

No association of TDP-43 with sporadic frontotemporal dementia

2007 • 40 citations

Truncated wild-type SOD1 and FALS-linked mutant SOD1 cause neural cell death in the chick embryo spinal cord

2005 • 28 citations

No association of chromatin-modifying protein 2B with sporadic frontotemporal dementia

2006 • 18 citations