Two Families with Familial Amyotrophic Lateral Sclerosis Are Linked to a Novel Locus on Chromosome 16q

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1993 • 6,762 citations

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

1998 • 3,377 citations

PedCheck: A Program for Identification of Genotype Incompatibilities in Linkage Analysis

1998 • 2,089 citations

Faster sequential genetic linkage computations.

1993 • 1,378 citations

From charcot to lou gehrig: deciphering selective motor neuron death in als

2001 • 1,373 citations

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

2001 • 722 citations

Natural history of amyotrophic lateral sclerosis in a database population Validation of a scoring system and a model for survival prediction

1995 • 683 citations

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

2001 • 660 citations

Computer-simulation methods in human linkage analysis.

1989 • 492 citations

High Prevalence of Mutations in the Microtubule-Associated Protein Tau in a Population Study of Frontotemporal Dementia in the Netherlands

1999 • 419 citations

Linkage of a Gene Causing Familial Amyotrophic Lateral Sclerosis to Chromosome 21 and Evidence of Genetic-Locus Heterogeneity

1991 • 373 citations

Linkage of Familial Amyotrophic Lateral Sclerosis With Frontotemporal Dementia to Chromosome 9q21-q22

2000 • 316 citations

SOD1 mutation is assosiated with accumulation of neurofilaments in amyotrophic lateral scelaries

1996 • 237 citations

Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33–q35

1994 • 202 citations

Linkage of the Gene for an Autosomal Dominant Form of Juvenile Amyotrophic Lateral Sclerosis to Chromosome 9q34

1998 • 188 citations

Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers

1998 • 169 citations

Mutations in all five exons of SOD‐1 may cause ALS

1998 • 150 citations

A Novel Locus for Familial Amyotrophic Lateral Sclerosis, on Chromosome 18q

2002 • 138 citations

Familial amyotrophic lateral sclerosis

1997 • 96 citations

Progress in the pathogenesis of amyotrophic lateral sclerosis

2001 • 62 citations

Motor Neuron Disease: Biology And Management

2011 • 38 citations

Motor neuron disease: Biology and management

1995 • 17 citations

Epidemiology of Motor Neuron Disease

1995 • 15 citations