Fatty acyl transfer by human N-myristyl transferase is dependent upon conserved cysteine and histidine residues.

Ser-His-Glu triad forms the catalytic site of the lipase from Geotrichum candidum

1991 • 534 citations

The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression

1984 • 381 citations

Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases

1994 • 308 citations

Protein N-myristoylation

1991 • 289 citations

Acylation of Proteins with Myristic Acid Occurs Cotranslationally

1987 • 274 citations

Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria.

1990 • 245 citations

Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.

1987 • 241 citations

The NH2 terminus of retinal recoverin is acylated by a small family of fatty acids.

1992 • 215 citations

Disruption of the Yeast N -Myristoyl Transferase Gene Causes Recessive Lethality

1989 • 190 citations

Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

1991 • 144 citations

Site-specific mutagenesis using asymmetric polymerase chain reaction and a single mutant primer

1990 • 129 citations

Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans.

1994 • 122 citations

In vitro synthesis of pp60v-src: myristylation in a cell-free system.

1988 • 118 citations

A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

1993 • 107 citations

The substrate specificity of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase. Analysis of myristic acid analogs containing oxygen, sulfur, double bonds, triple bonds, and/or an aromatic residue

1991 • 94 citations

Comparison of the acyl chain specificities of human myristoyl-CoA synthetase and human myristoyl-CoA:protein N-myristoyltransferase.

1993 • 71 citations

The Candida albicans myristoyl-CoA:protein N-myristoyltransferase gene. Isolation and expression in Saccharomyces cerevisiae and Escherichia coli.

1992 • 70 citations

Structural and functional studies of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase produced in Escherichia coli. Evidence for an acyl-enzyme intermediate.

1990 • 68 citations

Analyzing the substrate specificity of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase by co-expressing it with mammalian G protein alpha subunits in Escherichia coli

1991 • 67 citations

Isothermal titration calorimetric studies of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase. Determinants of binding energy and catalytic discrimination among acyl-CoA and peptide ligands

1994 • 52 citations

Studies of the catalytic activities and substrate specificities of Saccharomyces cerevisiae myristoyl-coenzyme A: protein N-myristoyltransferase deletion mutants and human/yeast Nmt chimeras in Escherichia coli and S. cerevisiae.

1992 • 50 citations

Characterization of a polyhistidine‐tagged form of human myristoyl‐CoA:protein N‐myristoyltransferase produced in Escherichia coli

1994 • 31 citations

The substrate specificity of Saccharomyces cerevisiae myristoyl-CoA: protein N-myristoyltransferase. Polar probes of the enzyme's myristoyl-CoA recognition site.

1994 • 27 citations