In vitro synthesis of pp60v-src: myristylation in a cell-free system.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Synchronised transmembrane insertion and glycosylation of a nascent membrane protein

1977 • 529 citations

Myristylation of picornavirus capsid protein VP4 and its structural significance

1987 • 475 citations

The Vertebrate Eye Lens

1977 • 449 citations

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

1984 • 447 citations

Cell Transformation by the Viral src Oncogene

1987 • 405 citations

n-Tetradecanoyl is the NH2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle.

1982 • 395 citations

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

1985 • 386 citations

CONTROLLED PROTEOLYSIS OF NASCENT POLYPEPTIDES IN RAT LIVER CELL FRACTIONS

1970 • 320 citations

Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylation

1979 • 319 citations

The covalent modification of eukaryotic proteins with lipid.

1987 • 319 citations

Ovalbumin: a secreted protein without a transient hydrophobic leader sequence.

1978 • 309 citations

CONTROLLED PROTEOLYSIS OF NASCENT POLYPEPTIDES IN RAT LIVER CELL FRACTIONS

1970 • 301 citations

Acylation of Proteins with Myristic Acid Occurs Cotranslationally

1987 • 274 citations

Identification of a polypeptide encoded by the avian sarcoma virus src gene.

1978 • 266 citations

Amino Terminal Myristylation of the Protein Kinase p60 src , a Retroviral Transforming Protein

1985 • 264 citations

Myristyl amino-terminal acylation of murine retrovirus proteins: An unusual post-translational protein modification

1983 • 263 citations

Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.

1987 • 241 citations

Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts.

1984 • 239 citations

Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog

1985 • 223 citations

Amino-terminal processing of proteins by N-myristoylation. Substrate specificity of N-myristoyl transferase.

1987 • 220 citations

Specificity of fatty acid acylation of cellular proteins.

1985 • 213 citations

An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins

1985 • 201 citations

Two classes of fatty acid acylated proteins exist in eukaryotic cells.

1985 • 196 citations

Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein.

1984 • 173 citations

DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src

1982 • 152 citations

Identification of the NH2-terminal blocking group of NADH-cytochrome b5 reductase as myristic acid and the complete amino acid sequence of the membrane-binding domain.

1984 • 145 citations

Highly specific antibody to Rous sarcoma virus src gene product recognizes a novel population of pp60v-src and pp60c-src molecules.

1985 • 133 citations

Fine structural mapping of a critical NH2-terminal region of p60src.

1985 • 129 citations

Translation of 35S and of subgenomic regions of avian sarcoma virus RNA.

1977 • 125 citations

Protein fatty acid acylation: enzymatic synthesis of an N-myristoylglycyl peptide.

1986 • 123 citations

Fatty acylation of cellular proteins. Temporal and subcellular differences between palmitate and myristate acylation.

1986 • 120 citations

Studies on the attachment of myristic and palmitic acid to cell proteins in human squamous carcinoma cell lines: evidence for two pathways.

1985 • 100 citations

Mechanism of compartmentation of secretory proteins: transport of exocrine pancreatic proteins across the microsomal membrane

1980 • 99 citations

The erythrocyte anion transport protein is cotranslationally inserted into microsomes

1982 • 92 citations

Acylation of cellular proteins with endogenously synthesized fatty acids

1986 • 73 citations

Product of in vitro translation of the Rous sarcoma virus src gene has protein kinase activity

1979 • 72 citations

11-(Ethylthio)undecanoic acid. A myristic acid analogue of altered hydrophobicity which is functional for peptide N-myristoylation with wheat germ and yeast acyltransferase.

1988 • 69 citations

Protein modification enzymes associated with the protein-synthesizing complex from rabbit reticulocytes. Protein kinase, phosphoprotein phosphatase, and acetyltransferase.

1977 • 56 citations

Mutations Altering Initiation of Translation of Yeast Iso-1-cytochrome c ; Contrasts between the Eukaryotic and Prokaryotic Initiation Process

1982 • 54 citations

Development and characterization of antisera specific for amino- and carboxy-terminal regions of pp60src

1985 • 10 citations