Phospholipase C-β1 Directly Accelerates GTP Hydrolysis by Gαq and Acceleration Is Inhibited by Gβγ Subunits

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃

1998 • 834 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 • 765 citations

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

1996 • 729 citations

New roles for G-protein (βγ-dimers in transmembrane signalling

1993 • 633 citations

RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits

1996 • 547 citations

Mammalian RGS Proteins: Barbarians at the Gate

1998 • 487 citations

Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator

1992 • 430 citations

RGS10 is a selective activator of Gαi GTPase activity

1996 • 354 citations

Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

1992 • 340 citations

Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

1998 • 296 citations

Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits

1993 • 262 citations

A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to G _β5 subunits

1998 • 260 citations

The N-terminal Domain of RGS4 Confers Receptor-selective Inhibition of G Protein Signaling

1998 • 235 citations

Regulation of Phospholipase C-β1 by Gq and m1 Muscarinic Cholinergic Receptor

1996 • 220 citations

GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain

1998 • 218 citations

Purification and characterization of two G-proteins that activate the beta 1 isozyme of phosphoinositide-specific phospholipase C. Identification as members of the Gq class.

1991 • 191 citations

Mutations of Gs α Designed to Alter the Reactivity of the Protein with Bacterial Toxins

1989 • 177 citations

Purification of unique alpha subunits of GTP-binding regulatory proteins (G proteins) by affinity chromatography with immobilized beta gamma subunits.

1990 • 169 citations

The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro

1997 • 167 citations

RGSZ1, a Gz-selective RGS Protein in Brain

1998 • 144 citations

Identification of the Gβ5-RGS7 Protein Complex in the Retina

1998 • 120 citations

Expression of GTPase-deficient Giα2 Results in Translocation of Cytoplasmic RGS4 to the Plasma Membrane

1998 • 78 citations

Modulation of the Affinity and Selectivity of RGS Protein Interaction with G_α Subunits by a Conserved Asparagine/Serine Residue

1999 • 78 citations

G ProteinsTechniques of Analysis

1999 • 69 citations

A GTPase-activating Protein for the G Protein Gαz

1997 • 64 citations

Kinetic control of guanine nucleotide binding to soluble Gαq

1999 • 51 citations