Inhibition of thyrotropin-induced DNA synthesis in thyroid follicular cells by microinjection of an antibody to the stimulatory G protein of adenylate cyclase, Gs.

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours

1989 • 1,405 citations

Two G Protein Oncogenes in Human Endocrine Tumors

1990 • 1,038 citations

Culture of hormone-dependent functional epithelial cells from rat thyroids.

1980 • 959 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Molecular Cloning of the Thyrotropin Receptor

1989 • 529 citations

Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas

1987 • 519 citations

The cyclic AMP-mediated stimulation of cell proliferation

1989 • 464 citations

Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains.

1986 • 427 citations

Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies.

1989 • 374 citations

Cloning, sequencing and expression of human TSH receptor

1990 • 297 citations

INSULIN-LIKE GROWTH FACTOR-I STIMULATES THE GROWTH OF RAT THYROID CELLS IN CULTURE AND SYNERGIZES THE STIMULATION OF DNA SYNTHESIS INDUCED BY TSH AND GRAVES′-IgG

1986 • 286 citations

The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist.

1988 • 273 citations

Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells.

1988 • 266 citations

gsp mutations in human thyroid tumours.

1991 • 198 citations

Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells.

1987 • 194 citations

Factors controlling proliferation and differentiation of canine thyroid cells cultured in reduced serum conditions: effects of thyrotropin, cyclic AMP and growth factors

1984 • 186 citations

Receptor and effector interactions of G_s Functional studies with antibodies to the α_s carboxyl‐terminal decapeptide

1989 • 176 citations

Identification of the GTP-binding protein encoded by Gi3 complementary DNA.

1988 • 169 citations

Thyrotropin and dibutyryl cyclic AMP increase levels of c-myc and c-fos mRNAs in cultured rat thyroid cells.

1986 • 140 citations

Adenosine 3′,5′-Monophosphate Mediates Both the Mitogenic Effect of Thyrotropin and Its Ability to Amplify the Response to Insulin-Like Growth Factor I in FRTL5 Cells*

1988 • 138 citations

Thyrotropin controls transcription of the thyroglobulin gene.

1984 • 117 citations

Induction of the c- fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

1986 • 111 citations

Stimulation by thyrotropin, cholera toxin and dibutyryl cyclic AMP of the multiplication of differentiated thyroid cells in vitro

1982 • 103 citations

Interaction of TSH, Insulin and Insulin-like Growth Factors in Regulating Thyroid Growth and Function

1990 • 96 citations

Norepinephrine and Thyroid-Stimulating Hormone Induce Inositol Phosphate Accumulation in FRTL-5 Cells

1986 • 82 citations

Inhibition of DNA synthesis in living cells by microinjection of Gi2 antibodies.

1992 • 60 citations

Thyroid-stimulating hormone and insulin-like growth factor-1 synergize to elevate 1,2-diacylglycerol in rat thyroid cells. Stimulation of DNA synthesis via interaction between lipid and adenylyl cyclase signal transduction systems.

1988 • 58 citations

Regulation of protooncogenes c-fos and c-myc expressions by protein tyrosine kinase, protein kinase C, and cyclic AMP mitogenic pathways in dog primary thyrocytes: A positive and negative control by cyclic AMP on c-myc expression

1990 • 57 citations

Novel Cyclic Adenosine 3′,5′- Monophosphate Response Element in the Human Chorionic Gonadotropin β-Subunit Gene

1991 • 57 citations

Induction of a cyclic AMP-responsive gene in living cells requires the nuclear factor CREB.

1991 • 56 citations

Control of c-fos and c-myc Proto-Oncogene Induction in Rat Thyroid Cells in Culture

1987 • 53 citations

TSH AND CAMP ENHANCE EXPRESSION OF THE MYC PROTO-UNCOGENE IN CULTURED THYROID CELLS

1985 • 53 citations

Thyrotrophin and the differential expression of proliferation and differentiation in dog thyroid cells in primary culture

1983 • 45 citations

Insulin stimulates cell growth of a new strain of differentiated rat thyroid cells

1987 • 44 citations

Insulin and Insulin-like Growth Factor I (IGF I) Stimulate Phosphorylation of a Mr 175,000 Cytoskeleton-associated Protein in Intact FRTL5 Cells

1989 • 41 citations

Enhancement of cmyc mRNA concentration in dog thyrocytes initiating DNA synthesis in response to thy rotropin, forskolin, epidermal growth factor and phorbol myristate ester

1986 • 37 citations

Thyrotropin effect on the availability of Ni regulatory protein in FRTL-5 rat thyroid cells to ADP-ribosylation by pertussis toxin

1987 • 32 citations

IGF-I increases C-fos expression in FRTL5 rat thyroid cells by activating the C-fos promoter

1988 • 31 citations

Variations in the Culture Medium for FRTL5 Cells: Effects on Growth and Iodide Uptake*

1989 • 31 citations

Chronic and acute effects of thyrotropin on phosphatidylinositol turnover in cultured porcine thyroid cells

1982 • 30 citations

Cloning and sequence analysis of TFE, a helix-loop-helix transcription factor able to recognize the thyroglobulin gene promoterin vitro

1991 • 24 citations

Adenosine Has Divergent Effects on Deoxyribonucleic Acid Synthesis in FRTL5 Cells: Inhibition of Thyrotropin-Stimulated and Potentiation of Insulin-Like Growth Factor-I-Stimulated Thymidine Incorporation*

1989 • 18 citations

The Deoxyribonucleic Acid Regions Involved in the Hormonal Regulation of Thyroglobulin Gene Expression*

1991 • 14 citations

Calf serum modifies the mitogenic activity of epidermal growth factor in WRT thyroid cells

1989 • 13 citations