Induction of a cyclic AMP-responsive gene in living cells requires the nuclear factor CREB.

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

1988 • 1,321 citations

Major nucleolar proteins shuttle between nucleus and cytoplasm

1989 • 1,113 citations

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

1990 • 1,061 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

A cyclic AMP- and phorbol ester-inducible DNA element

1986 • 780 citations

Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains.

1986 • 427 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

MINIREVIEW: Cyclic AMP Response Element Binding Proteins: A Cornucopia of Transcription Factors

1990 • 394 citations

Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

1987 • 293 citations

A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters.

1987 • 284 citations

Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells.

1988 • 266 citations

Characterization of a bipartite activator domain in transcription factor CREB

1990 • 228 citations

Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation.

1990 • 226 citations

Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins.

1988 • 198 citations

Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.

1987 • 189 citations

The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements

1988 • 186 citations

The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer.

1988 • 181 citations

The gonadotropin alpha-gene contains multiple protein binding domains that interact to modulate basal and cAMP-responsive transcription.

1988 • 127 citations

Transcriptional regulation of a plasminogen activator gene by cyclic AMP in a homologous cell-free system. Involvement of cyclic AMP-dependent protein kinase in transcriptional control.

1988 • 51 citations

Microinjection and organelle transplantation techniques: Methods and applications

1987 • 29 citations

Deleted Work

1955 • 0 citations